Asklepios Neurologische Klinik Falkenstein

A59-year-old male patient was admitted for possible reflex syncope following loss of consciousness during urination. During the visit, amalaise with unconsciousness occurred. Holter ECG at that time showed increasing sinus bradycardia with transition to ajunctional escape rhythm (30/min); in addition, there were several sinus pauses > 2.0 s (the longest almost 10 s). This malaise occurred again during routine EEG, when afocal epileptic seizure on the right fronto-temporal with sinus bradycardia after 15 s was documented. Thus, the diagnosis of ictal asystole was made, anticonvulsant therapy was started, and acardiac pacemaker was implanted.

Metalworkers are exposed to a variety of contact allergens by handling tools, metals, metalworking fluids (MWFs), oils and greases, rubber materials, and so on. Most large-scale reports on contact allergy due to MWFs are more than 10-years-old, and there are only few studies on contact allergy in mechanics and other metal workers not exposed to MWFs. To describe a current spectrum of contact sensitization in metalworkers with occupational dermatitis (OD). Retrospective analysis of patch test data collected by the Information Network of Departments of Dermatology (IVDK; 2010-2018), stratifying for 804 cutting metalworkers, 2197 mechanics, and 355 other metalworkers. Cutting metalworkers were most frequently sensitized to monoethanolamine (12.6%), colophonium/abietic acid (11.4%) and formaldehyde releasers (up to 8.5%) from the MWF series, and formaldehyde (4.6%) and iodopropynyl butylcarbamate (4.6%) from the baseline series. Sensitization among mechanics and other metalworkers indicates possible occupational exposure to MWFs, glues, and resins, although this may not be expected from their job titles. The spectrum of MWF contact allergens remained largely unchanged during the last years. Taking a comprehensive occupational history is indispensable in order to not miss relevant allergen exposures.

Stroke is the main cause of permanent and complex long-term disability in adults. RETRAINER S2 is a system able to recover and support person’s ability to perform Activities of Daily Living (ADL) in early stage after stroke. The system is based on exercises for hand and wrist performed using Neuro Muscular Electrical Stimulation (NMES). This work describes the preliminary results of a multi-center Randomized Controlled Trial (RCT) aimed at evaluating effectiveness of the system. The preliminary results were calculated on 18 patients who completed the protocol. Data is promising, the RETRANER S2 system seems to be a good tool for stroke rehabilitation. Data confirms also a general good usability of the system.

Körperliche Aktivitäten im moderat-intensiven und hoch-intensiven Bereich sind entsprechend internationaler Aktivitätsempfehlungen für gesundheitliche Effekte relevant. COPD-Patienten zeigen ein geringes Ausmaß an entsprechenden körperlichen Aktivitäten (PA) (Demeyer et al., 2017).

Illness-specific self-efficacy is important in the disease-management of patients with COPD (Chronic Obstructive Pulmonary Disease). Nevertheless, there is no instrument to measure the illness-specific self-efficacy in the German speaking countries. The purposes of the study were to translate the COPD Self-Efficacy Scale (CSES) into German (CSES-D) and to determine the psychometric criteria. Another objective was to construct a short form of the CSES-D. A total of 199 participants with COPD were recruited. The factorial structure of the CSES including 5 dimensions could not be confirmed with exploratory and confirmatory factor analyses. However, the short form of the CSES-D indicated acceptable fit indices. The internal consistencies of the subscales psychological stress (α=0.95) and physical exertion (α=0.92) were good. The correlations between the CSES-Dkurz and convergent and discriminant questionnaires confirmed the validity of the instrument. The results indicate that the CSES-Dkurz is a valid and reliable instrument to assess illness-specific self-efficacy of COPD-patients. Further, studies are needed to verify the factorial construct validity of the CSES-Dkurz.

Die Auswirkungen von Lebensstilfaktoren wie korperliche Aktivitat und Ernahrung auf Entstehung und Verlauf von Krebs ist seit uber 60 Jahren Gegenstand klinischer und epidemiologischer Forschung. Obwohl viele Fragen noch offen bleiben, ermoglichen aktuelle Studien evidenzbasierte Empfehlungen fur die primare und tertiare Krebspravention. Im Rahmen einer Literaturrecherche wurden Ubersichtsarbeiten zum Einfluss von korperlicher Aktivitat und Ernahrung auf Krebs sowie Studien zu aktuellen Entwicklungen in diesen Themengebieten identifiziert. Korperliche Aktivitat tragt zur primaren Pravention von Kolonkarzinomen, postmenopausalem Brustkrebs und Endometriumkarzinomen bei. Der vermehrte Verzehr von rotem Fleisch und verarbeiteten Fleischprodukten ist mit einer Erhohung des Krebsrisikos assoziiert. Eine obst-, gemuse- und ballaststoffreiche Ernahrung hangt demgegenuber mit einer Senkung des Krebsrisikos zusammen. Korperliche Aktivitat kann wahrend jeder Therapiephase unter Berucksichtigung der individuellen Probleme durchgefuhrt werden. Studienergebnisse berichten von verbesserter Leistungsfahigkeit und Lebensqualitat, einer Verminderung von therapieassoziierten Nebenwirkungen sowie Senkung des Rezidivrisikos durch eine korperliche Aktivitat. Evidenzbasierte Empfehlungen zur Krebspravention durch korperliche Aktivitat und Ernahrung sollen in die Behandlung von onkologischen Patienten und in die Versorgung der Allgemeinbevolkerung integriert werden. Innovative Programme wie „Jetzt aktiv!“, die kompetente Beratung bezuglich Ernahrung und korperlicher Aktivitat nach einer Krebserkrankung anbieten, werden an Krebsberatungsstellen entwickelt und erfolgreich eingesetzt.