Ayurvet (India)

Present study focused on evaluating heavy metal accumulation potential of invasive plant species growing near an ash disposal site of a thermal power station. A total number of 8 invasive plant species (weeds) were collected and screened for heavy metal (Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Cd, and Pb) accumulation. Results showed that the soil was slightly acidic (pH -6.8) with a high concentration of Fe (10133 mg kg-1dw) while the concentrations of Mn and Cu were (72 and 51 mg kg-1dw)respectively. The bioaccumulation of heavy metals varied in various plant species.The maximum level of Fe (988 mg kg-1dw) and Ni (11 mg kg-1dw) was found inSolanumnigrum and Euphorbia prostrata, respectively. Ageratum conyzoides was the most efficient plant for metal accumulation from FA-contaminatedsites among all species. In general, the concentration of heavy metals was higher in shoots than in roots for most of the plants which means that these plant species can be usedfor phytoextraction of heavy metals, thus helping in the phytoremediation of fly ash-contaminated soil.

The present investigation was conducted on cattle suffering from fever at Veterinary Clinical Complex, Apollo College of Veterinary Medicine, as well as in animals of individual house holding in Jaipur district of Rajasthan to evaluate the anti-inflammatory and anti-pyretic efficacy of herbal formulation AV/AAC/18 which was provided by M/s. Ayurvet Limited, India. In this trial, a total 30 cattle affected with fever were randomly allocated to control (Group 1) and treatment group (Group T1) having fifteen cattle in each group. Group T1 was treated with injection enrofloxacin @ 5 mg /kg, b.wt., bid, i.m. + AV/AAC/18 @ 50 ml, p. o., bid, till recovery and Group 1 was treated with injection Enrofloxacin @ 5 mg /kg, b.wt., i.m., bid, injection- Melonex plus (meloxicam + paracetamol) @ 1 ml/10 kg b.wt., i.m., bid., till recovery. Various parameters viz. rectal temperature, respiration rate, pulse rate, heart rate, rumination frequency, feed consumption per animal were recorded pre-treatment and post-treatment. It was observed that AV/AAC/18 showed comparable therapeutic effect with allopathic drug in management of fever and inflammation in cattle. Looking to the recovery status in rectal temperature, respiration rate, pulse rate, heart rate, rumination frequency, frequency and consistency of dung, feed consumption in treatment group it was concluded that product AV/AAC/18 was efficacious in improving from fever and inflammation and can be used along with antibiotics therapy for management of fever and inflammation in cattle.

This study aimed to compare the efficacy of supplementation with a synthetic (DL-α-tocopherol acetate) or herbal source of vitamin E on performance of broiler chicken during a 35-days feeding trial. Day-old broiler chicks (180) were randomly assigned to one of four treatment groups, each with three replicates. T1 (control) received a basal diet, Group T2 received a basal diet with synthetic vitamin E @ 100 g/quintal of feed, Group T3 received a basal diet with herbal vitamin E @ 100 g/quintal of feed and Group T4 received a basal diet with synthetic vitamin E @ 50 g/ quintal of feed + herbal vitamin E @ 50 g/quintal of feed. Supplementation of herbal vitamin E enhanced growth performance traits (average weight gain, feed intake, feed conversion ratio and economics of broiler production), retention of nutrients (dry matter, nitrogen, and ether extract), haematological parameters (Hb, PCV, and TEC) and serum total cholesterol in broiler chicks. Antioxidant status revealed significant increase in GSH but not SOD and CAT. A marked increase in the antibody titer against Newcastle Disease vaccine was recorded in the herbal vitamin E supplemented group. The carcass quality was statistically similar among different dietary treatments, however, lowest abdominal fat and meat cholesterol were recorded in the group supplemented with herbal vitamin E. The study depicts that dietary supplementation of synthetic or herbal vitamin E and their combination @ 100 g/quintal of feed improved the growth performance, antioxidant status and carcass quality of broiler chickens; and that herbal vitamin E was economical and more effective as compared to the synthetic vitamin E in improving the performance of broiler chickens.

In present communication pharmacognostic specification of medicinal plants used in veterinary products have been described for the purpose of their standardization. The plants undertaken for the study were Abroma augusta stem (Sterculiaceae) and Cissus quadrangularis (Vitaceae). These plants are official in Ayurvedic Pharmacopoeia of India. The observed microscopic characters of Abroma augusta stems are suberized cork cells, pericyclic fibers, polygonal parenchymatous cells. Microscopic characteristics of Cissus quadrangularis aerial part shows chlorenchymas hypodermis, sclerenchyma sheath; large cells of mucilage along with clusters and bundles of acicular crystals of calcium oxalate were seen in abundant and were scattered throughout the section. Powder microscopy of both the plants was also studied and identifying features were noted down. The improved qualitative microscopic features would prove useful for their quick identification and laying down their pharmacopoeia standards. Additionally, present study also provides the information with respect to crude drug and may serve as a reference point for the proper identification of Abroma augusta stems and aerial parts of Cissus quadrangularis. The present study would also fill the gap in providing evidential support concerning quality determination of plant material used in veterinary medicinal product. Emphasis is upon aiming to increase documentation on primary studies on medicinal plants used in veterinary medicines.

This study was undertaken to evaluate the acute dermal toxicity of a topical anti-mastitis gel (Mastilep® gel; M/s Ayurvet Limited, India) in accordance with OECD 402 guidelines. Nine adults female Wistar rats, weighing 210-250 g, were used in the study. Following the topical application of the anti-mastitis gel, the animals were observed for the manifestation of toxic effects and mortality. Toxicity was evaluated on the basis of changes in body weight, histological appearances of heart, liver, kidney, and lungs, and blood biochemical parameters viz. AST, ALT, ALP and creatinine. Since no toxic effects or deaths were recorded until completion of the experiment, the anti-mastitis gel was found safe for dermal use.

The objective of this study was to assess the acute oral toxicity of AV/SGB/27 (M/s Ayurvet Limited) in accordance with OECD-423 guideline. AV/SGB/27 is a herbal formulation for enhancing semen quality of livestock. Nine healthy and adult nulliparous nonpregnant Swiss albino female mice, weighing 24-28 g, were used in this study. After being given test material orally, the mice were examined for toxic effects and mortality. Changes in body weights, symptoms of toxicity, histological appearances of liver, kidney, and lungs, and biochemical parameters were used to assess the toxicity. No toxic effects or mortalities were noticed until the trial was completed, indicating that AV/SGB/27 is safe for oral consumption.

One-hundred and fifty, one-day-old Ross-308 female chicks were randomly allocated to five equal treatments: NCONTR negative control—not challenged; PCONTR positive control—challenged; PHERB1 and PHERB2 diets were supplemented with phytogenic formula (1 and 2 g/kg feed, respectively)—challenged; PSALIN diet was supplemented with salinomycin (60 mg/kg feed)—challenged. Challenge was made by oral inoculation with 3.5 × 104E. acervulina, 7.0 × 103E. maxima and 5.0 × 103E. tenella oocysts, at 14 days of age. One week post inoculation, bloody diarrhea, oocysts numbers, and intestinal lesions were evaluated, along with intestinal microbiota, viscosity, and pH of digesta, and histopathology. PHERB2 had a comparable (p ≤ 0.001) growth performance and feed conversion ratio to PSALIN. PHERB1 and PHERB2 had similar (p ≤ 0.001) oocyst counts to PSALIN and lower than PCONTROL. PHERB2 and PSALIN had lower (p ≤ 0.001) jejunal, ileal, and cecal lesion scores compared to PCONTR. PHERB1 and PHERB2 had higher (p ≤ 0.001) jejunal and cecal lactobacilli and lower (p ≤ 0.001) coliform counts compared to other treatments. PCONTR had lower (p ≤ 0.001) jejunum villus height, height to crypt ratio, and villus goblet cells. Breast and thigh meat resistance to oxidation was improved (p ≤ 0.001) in PHERB1 and PHERB2 compared to the PCONTR. The polyherbal formula exerted a substantial improvement on growth performance and intestinal health of the Eimeria-challenged birds.

Mycotoxins are biologically active, toxic metabolites produced by toxigenic fungi mainly belonging to genus Aspergillus, Fusarium and Penicillium. They are ubiquitous in poultry feeds. Mix-02-Tox is a broad-spectrum mould inhibitor and mycotoxin binder, recommended for complete protection against multiple mycotoxins and for better production in poultry, cattle and pigs. A study was undertaken to evaluate the acute oral toxicity potential of Mix-02-Tox (M/s Ayurvet Limited, India) according to OECD 423 guidelines. Six (3 male and 3 female) Swiss albino mice were used for the study, where each animal served as its own control. Following the oral administration of the test substance, the animals were observed for the manifestation of toxic effects and mortality. No toxic effects or mortalities were observed till 14 days and Mix-02-Tox was found to be safe for oral use.

Immunity means the natural body mechanism through which our body protects itself from various diseases. According to Ayurveda there are many factors which contribute to our immunity. One of such things is the “Oja”. According to Ayurveda there are 7 basic body tissues which form the human body and all the functional systems of the body, these are; Rasa (Nutritive Fluid), Rakta (Blood), Mamsa (Muscles), Meda (Lipids), Asthi (Bones), Maja (Marrow) and Shukra (Reproductive cells). These are known as the “SaptaDhatu”. The essence of these 7 tissues is known as “Oja”. And if this Oja is in a balanced state and functioning properly you won’t have any disease.