Bangladesh Jute Research Institute

Tumor and cancer research in Bangladesh is an evolving field with both steady progresses recently and significant challenges. The 2013 Series Bangladesh: Innovation for Universal Health Coverage, published in The Lancet, reported on Bangladesh’s health achievements and challenges particularly on exceptional health advances at low cost than other countries in Asia. Additionally, several national and subnational studies have reported the burden of different diseases and risk factors in Bangladesh at different points during the past three decades i.e. from 1990 to 2019 in Bangladesh. Cancer is a leading cause of death of children and adolescent worldwide and it represents one of the most significant public health problem and challenges of the century with a particularly devastating impact on developing nations. Several studies have been reported evaluating qualitatively and quantitively documenting research progress on tumors and cancers situation from Bangladesh. In the present article, we have made an overview of this field with background to burden of diseases and risk factors, some reported studies from Bangladesh on tumors and cancers and steady research progress on tumors and cancers and significant challenges to it in Bangladesh. Further continued research affords along these fronts are therefore warranted and vitally important.

A field study was carried out during the 2024–2025 season at two experimental sites the Jute Agriculture Experimental Station in Manikganj and the Jute Research Regional Station in Rangpur to assess how different sowing dates and plant spacings influence the seed yield and yield-related traits of BJRI Deshi Pat Shak-1 (BJC-390). The treatments comprised three sowing dates (1st August, 11th August and 22nd August) and three spacing levels (30 cm × 20 cm, 35 cm × 20 cm, and 40 cm × 20 cm), arranged in a randomized complete block design (RCBD) with three replications. Results revealed that 11th August sowing at 30 cm × 20 cm spacing produced the highest seed yield (630 kg ha⁻¹) at Rangpur, associated with the highest pod and seed numbers per plant. In contrast, the lowest seed yield (400 kg ha⁻¹) was observed in the 22nd August sowing with 40 cm × 20 cm spacing. In Manikganj, spacing and sowing dates had less pronounced effects on yield, although wider spacing (40 cm × 20 cm) combined with early sowing showed relatively higher productivity. The findings suggest that mid-August sowing combined with closer spacing is optimal for maximizing seed yield of BJRI Deshi Pat Shak-1, particularly in Rangpur agroecological conditions.

The integration of Information Technology (IT) investments and business analytics has become a cornerstone in reshaping healthcare performance, driving both operational efficiency and improved patient outcomes. As healthcare systems grapple with rising costs, regulatory complexities, and evolving patient demands, the strategic alignment of IT with business objectives emerges as a critical determinant of success. Financial and non-financial metrics, including return on investment, patient safety, workflow efficiency, and quality of care, are increasingly used to evaluate the impact of IT expenditures. However, organizations face persistent challenges, including escalating labor costs, cybersecurity threats, regulatory compliance, and difficulties in workforce recruitment and retention. Business analytics plays a transformative role in decision-making, leveraging predictive models and statistical tools to enhance disease detection, personalize treatment, optimize resource allocation, and reduce operational inefficiencies. To maximize value, organizations must employ structured frameworks that include identifying key performance indicators (KPIs), implementing robust monitoring systems, and embedding continuous improvement cycles. Effective integration of IT and analytics not only strengthens patient-provider relationships but also supports long-term sustainability and competitiveness in a resource-constrained environment. Looking ahead, emerging trends such as digital transformation, artificial intelligence, telemedicine, and patient-centric care models will further shape healthcare delivery. Strategic risk management, workforce development, and proactive regulatory adaptation will be pivotal for leveraging these innovations while safeguarding patient trust. Ultimately, the successful fusion of IT investment and analytics represents a vital pathway to achieving measurable improvements in healthcare performance, organizational resilience, and patient outcomes.

In this work, a UV spectrophotometric approach that is accurate, precise, and environmentally friendly Is proposed for concurrent quantification of Ritonavir and Nirmatrelvir in combination pharmaceutical form. While treating COVID-19, these antiviral medications are essential. The Q-absorbance method was created and validated in accordance with ICH criteria, and the simultaneous estimation method is constructed utilizing two distinct solvents. After being evaluated for linearity, accuracy, precision, robustness, and sensitivity, the suggested techniques showed great reproducibility and high correlation coefficients (r2 = 0.999). One-way ANOVA statistical comparison verified that the devised methodologies were reliable and consistent for pharmaceutical analysis, with no significant differences found.Furthermore, the Green Analytical Procedure Index (GAPI), AGREE, and BAGI criteria were used to assess the Ecological sustainability of these methods. The results demonstrated that the suggested approaches provide a greener substitute for traditional analytical procedures by drastically lowering solvent usage and the production of hazardous waste. The proposed UV spectrophotometric approaches offer a straightforward, economical, and dependable solution for the routine quality evaluation of Ritonavir and Nirmatrelvir in dosage forms.

Since geese (Anser anser) are herbivorous waterfowl, their gizzards are larger and stronger, Allowing them to break down high-fiber roughages with greater force and consume enormous volumes of forages. The goal of this study was to evaluate the effectiveness of water spinach (Ipomoea aquatica) in identifying the water-holding capacity, meat nutrient composition, pH, drip loss, cooking loss, slaughter and carcass characteristics and meat colour of local Bangladeshi white and grey geese varieties supplemented with varying amounts of water spinach. A semi-intensive production system was used to raise 36 adult geese of both white and grey kinds, which were slaughtered at 28 weeks of age. They were split into four groups at random, each consisting of three replicates with three geese each. Maize soya-based diet was considered as control diet (CL) (2700ME/Kcal, 16% CP) where T1 & T3 group were given 180g of CL diets in white and grey variety respectively and other diets included T2 (White variety)-80g of water spinach + 140g of CL diet, T4 (Grey variety)- 80g of water spinach + 140g of CL diet. Following rearing, each bird was weighed separately. Treatments significantly affected the redness value (a*) (p < 0.05). A statistical analysis was performed on 12 slaughter traits, which were separated into two groups: measured traits and calculated traits. For slaughter traits, results suggested that beneficial trails were not significantly varied but tented to be higher in the supplemented group. pH value for T3 group was higher than other groups. Additionally, supplemented group showed lowest drip loss and cooking loss and best water holding capacity, but these parameters were not significantly veried. Notably, the supplemented groups had exhibited the highest dressing percentage, desirable slaughter and carcass traits as well as favourable meat quality parameters. Taking these factors into account, we can say that adding water spinach to geese improved their slaughter and carcass characteristics, meat colour, pH, drip loss, cooking loss, water-holding capacity and meat nutritional content. Bang. J. Livs. Res. Vol. 30 (1&2), 2023: P. 23-35

Transdermal drug administration is a method of administering medication through the skin that is non-intrusive, offering an innovative and hopeful alternative to traditional oral and injection methods. Advancements in skin penetration technology have enabled the transdermal administration of various anticancer medications, including lipophilic or hydrophilic compounds, offering a new approach to cancer treatment. Research has explored innovative platforms for cancer treatment, such as erythrocytes, vesicles, and exosomes. The most efficient approach is the transdermal drug delivery system. This review investigates various transdermal delivery techniques beyond the pharmaceutical sector in relation to cancer treatment. Techniques include iontophoresis, electroporation, sonophoresis, microneedles, transdermal patches, or vesicular systems like liposomes, niosomes, transferosomes, ethosomes, transethosomes, nanoparticles, carbon nanotubes, quantum dots, as well as nanofibers, which have been used to improve transdermal distribution and their use in cancer treatment. Additionally, a roadmap is presented to guide development strategies, highlighting the multiple applications of transdermal drug administration systems for cancer therapy.

Acute urticaria as the sole initial manifestation of dengue fever: A rare case reportMd Osman Gani1, Mohammad Shahangir Biswas2,3*, Md Moyen Uddin PK4,5, Md Ebrahim Khalil2, Maksudul Haque2, Md Matiar Rahman61Department of Biochemistry & Molecular Bio

The temperature-sensitive industries including healthcare, agriculture and cold chain logistics the Internet of Things (IoT) has greatly increased monitoring and management of environmental conditions. Minor temperature fluctuations can lead to the deterioration of products, diminished effectiveness of pharmaceuticals, or suboptimal agricultural results. This work presents the design and development of a thermologger system for real-time temperature monitoring and data recording system based on the Internet of Things (IoT). The Internet of Things (IoT) has emerged as a revolutionary solution, facilitating real-time monitoring, sophisticated analysis and automated decision-making across several sectors. The system incorporates low-power digital temperature sensors, a microcontroller unit (MCU) and a wireless communication module based on the ESP-8266. These components work together to collect temperature data and transmit it to a cloud platform for storage and analysis. A key feature of the system is its user-friendly interface, available through a mobile app and a web dashboard. These platforms enable users to view temperature trends, receive alerts when temperatures fall outside of safe ranges and generate reports for further analysis. The alert mechanism is especially useful in high-risk areas such as vaccine storage, greenhouse operations, large industrial cold storage, datacenter and food transportation where timely intervention can prevent significant loss. Real-world testing demonstrates the system’s accuracy, responsiveness, and dependability. These findings validate the system’s efficacy and affordability as a continuous temperature monitoring solution for critical applications. All things considered the proposed thermologger system may enhance operational decision-making, boost safety and optimize resource use across a range of industries.

Background and objective: Plateletpheresis involves the separation of platelets from healthy donor blood, with the remaining components returned to the donor’s circulation. With the increasing demand for aphaeretic platelets, the transfusion medicine department plays a crucial role in ensuring the availability of safe blood products when required. This study aimed to determine the frequency and underlying reasons for donor deferral during plateletpheresis. Materials and Methods: This study was conducted in the Transfusion Medicine Department of BIRDEM General Hospital in Dhaka from January 2021 to December 2022. Apheresis donors of either sex who attended the department were selected and evaluated for deferral by physicians in accordance with the Standard Operating Procedure (SOP) outlined in the hospital protocol [1]. Data on deferred plateletpheresis donors were recorded manually in a register book and analyzed retrospectively. Results: A total of 318 plateletpheresis donors were screened during this study period, of whom 43 (13.52%) were deferred for various reasons. The majority of the deferrals (93.9%) were temporary. The major causes of donor deferral were poor venous access (27.7%, mostly in females), low platelet count (16.2%), and the use of medications, most commonly analgesics, at 11.4%. Conclusion: This study demonstrated that venous access plays a vital role in donor deferral. Additionally, low platelet count and use of antiplatelet drug can significantly impact the apheretic donor eligibility. Revising the selection criteria for plateletpheresis donors could substantially enhance donor participation and reduce deferral rates. Furthermore, continued efforts to provide advanced training for technical personnel and ensure effective supervision by Transfusion Medicine Specialists will contribute to minimizing donor deferrals. July 2025; Vol. 19(2):003. DOI: https://doi.org/10.55010/imcjms.19.012 *Correspondence: Farida Parvin, Department of Transfusion Medicine & Clinical Haematology, BIRDEM General Hospital, Dhaka, Bangladesh. E-mail: dr.farida1984@gmail.com. © 2025 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0).