BioAxis DNA Research Centre (India)

M5-tracking, IoT systems are commonly used by fleet (Dementia, elderly, visually impaired, and intellectual disabilities operate as a unit) operators for fleet management functions such as fleet tracking, routing, dispatching, on-board information, and security. Some dementia, elderly, visually impaired, and intellectual disabilities tracking systems are bundled with or interface with fleet management software. A tracking unit is a device that uses the Global Positioning System to determine the precise location of dementia, elderly, visually impaired, and intellectual disabilities or other assets to which it is attached and to record the asset’s position at regular intervals. The recorded location data is transmitted to a central location Server connected to the Internet using a cellular (GPRS) modem embedded in the unit. This allows the Dementia, elderly, visually impaired, and intellectual disabilities’ location to be displayed on a map in real-time or when analyzing the track later, using GPS tracking software.

Dementia and intellectual disability persons have developmental deficiencies that are defined by intelligent and adaptive behavioral restrictions. This work goes toward assessment and management, incorporating the genetic and environmental philosophies of intellectual impairment of intellectual disability and dementia. This paper also highlights the requirements of persons with intellectual impairments, proposes an inter-professional approach to intellectual disability and dementia treatment, and recognizes the role of the professional team to manage these cases as they may eventually become a continuing disease.KeywordsDementiaManagementIntellectual disability

In order to develop any diagnostic or therapeutic protocol for COVID19 it is necessary to study the genome and proteome of the NCoV and annotate the proteins to identify its phylogeny and evolutionary relation with the other known organisms. The SARS NCoV and MERS Corona Virus belong to the Corona group of viruses and both are known to cause Respiratory illness. There is a very close similarity in the disease manifestation and mode of transmission in MERS and COVID forming basis for the comparison between the two organisms. Hence the proteins of novel Corona virus are compared with those of MERS Corona Virus (Fig. 3.1).

The detailed structural analysis of the ORF1ab polyprotein was carried out to study its Physiochemical characterization as well as its domain annotations.

Changed Converting distances matrix will load id2label lookup into memory to speed up conversion

Severe acute respiratory syndrome (SARS) is a serious form of pneumonia which results in acute respiratory distress and sometimes death. In this study, we applied the reverse vaccinology approach to determine the antigenic determinant sites present on the protein. The method incorporates the prediction of antigenic sites, solvent accessible region and secondary structure, B-cell epitope prediction, and the designing of antigenic determinant. The results of the study suggested that small envelope protein and orf8 protein could be potential candidates for vaccine designing. The high scoring antigenic peptides were designed and optimized. It is inferred that peptide of small envelope protein will make a very stable and effective vaccine targeting the E protein of the virus which is responsible for the spread of the virion. This study provides a strong and a potential optimized vaccine against SARS, which has high chances of success of immunization and higher probabilities of combating the dreadful disease.