- Book Chapter
1
- 10.1021/bk-2011-1062.ch009
Protein Microarray Substrates with High Interfacial Area Using Silica Colloidal Crystals
- Jan 01, 2011
- Mary J Wirth + 3 more +3
Protein microarrays are growing in use in biomedical research because proteins are more directly representative of physiological processes. There is a need for higher sensitivity because proteins, unlike DNA, cannot be amplified in concentration as simply. A thin layer of silica colloidal crystal provides a combination of high surface area and high optical transparency, promising unprecedented sensitivities for protein microarrays.
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