- Research Article
11
- 10.2460/javma.1981.179.11.1144
Glutaraldehyde Coagulation Test for Detection of Hypogammaglobulinemia in Neonatal Nondomestic Ruminants
- Dec 01, 1981
- Journal of the American Veterinary Medical Association
- Katherine I O'rourke + 1 more +1
SUMMARY Sera were collected from 103 individuals of 26 species of nondomestic ruminant animals in 2 zoological collections. Eighteen were presumed not to have absorbed colostral proteins (group 1), 32 had consumed colostrum at least 12 hours before testing (group 2), and 53 were healthy adults (group 3). The γ-globulin concentration, as determined by zone electrophoresis, was ≤0.4 g/dl in 16 of 18 samples from the group 1 animals, and > 0.4 g/dl in 31 of 32 group 2 animals. The glutaraldehyde coagulation test was performed on each serum sample. The results were negative in 15 of 17 samples, with γ-globulin concentration ≤0.4 g/dl, and positive in 85 of 86 samples, with γ-globulin concentration >0.4 g/dl. The glutaraldehyde coagulation test appeared to be a practical field test for determining failure of passive transfer of maternal antibody in newborn nondomestic ruminant animals in zoological collections.
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