Business Region Göteborg (Sweden)

ABSTRACTIntroductionThis study aims to investigate the association between young children receiving hospital treatment for burn injuries and their parents’ education levels.MethodA retrospective register study collected data using diagnostic codes (T20–T25 and T29) for children seeking emergency medical care for burn injuries between 2018 and 2022. T20–T25 and T29 refer to burn injuries, where each number specifies the affected body region. An additional selection was made using ICD code chapters S and T for overall injury‐related hospital care. The inclusion criteria for this study were children aged 0–6 years who had received emergency or specialised care at Queen Silvia Children's Hospital. The education levels of parents, as well as those of children who received care at the hospital, were grouped and aggregated at the area level. Parental education level data were obtained from Gothenburg's public statistical database to determine education levels in the city's areas. The mean of these two variables was calculated, and a simple linear regression was conducted. Data were aggregated and analysed at the intermediate area level rather than the individual level.ResultsThe results showed an association between children's burn injuries and parents’ education levels; however, parental education level and overall injury‐related hospital care were not associated with eachother.ConclusionsThis study demonstrated an association between burn injuries and parental education levels, which needs consideration in clinical practice and future research. Future efforts should explore targeted health literacy and parental support interventions in low‐education areas.

<strong class="journal-contentHeaderColor">Abstract.</strong> Sedimentary recycling of phosphorus is a key aspect of coastal eutrophication. Here, we present data on benthic fluxes of dissolved inorganic phosphorus (DIP) from the Baltic Sea, an area with a long eutrophication history. The presented dataset contains 499 individual fluxes measured in situ with three types of benthic chamber landers at 59 stations over 20 years, and data cover most of the Baltic Sea sub-basins (Hyl&eacute;n et al., 2025; <a href="https://doi.org/10.5281/zenodo.14812160" target="_blank" rel="noopener">https://doi.org/10.5281/zenodo.14812160</a>). The dataset further contains information about bottom-water dissolved oxygen (O₂) concentrations, sedimentary organic carbon (OC) content and sediment type. The DIP fluxes differ considerably between basins depending on OC loading and the level of O₂ depletion and generally increase from the coast to the central basins. Several stations have been visited on multiple occasions, also at times with different O₂ concentrations, which enables investigation of the immediate effects of shifting bottom-water O₂ concentrations on the benthic DIP release. The Baltic Sea-wide benthic DIP release is estimated to be 391 &ndash; 489 kton y^-1 based on a data integration based on sediment type and O₂ conditions during three years with varying extents of hypoxia and anoxia (2004, 2013 and 2018). The dataset reveals a lack of flux measurements in winter months, coastal areas and sandy sediments; these should be targeted in future studies. Overall, the data is of high quality and will be important for marine management and studies on mechanisms in benthic phosphorus cycling.

ABSTRACT This study assesses the impact of group therapy on young survivors of sexual abuse at a youth clinic in Sweden, focusing on self-reported outcomes and implications for primary health care. Interviews with 12 female participants aged 17–24 provided insights into the benefits of group therapy, including reduced feelings of loneliness and shame, enhanced understanding of abuse reactions and trajectories, and improved coping mechanisms. The findings support integrating group therapy into primary care settings alongside individual counseling, emphasizing the need for accessible, youth-oriented services with robust referral systems to effectively address the comprehensive psychosocial and health needs of young survivors.

This study examines how third-party environmental, social, and governance (ESG) assurance and ESG performance influence credit risk. Using a European dataset of 1,448 firm-year observations, we find that third-party ESG assurance improves credit ratings indirectly by enhancing ESG performance, consistent with monitoring theory. In line with the risk mitigation view of ESG investment, we further document that superior ESG performance is associated with a lower credit risk. These findings have important implications for the ongoing debate on ESG and its independent assurance across academic, policy, and industry domains. The pronounced role of ESG performance in reducing credit risk is relevant not only for firms but also for credit rating agencies, who can incorporate ESG-related factors to capture a broader spectrum of risks and opportunities. Moreover, policymakers may leverage the monitoring function of third-party ESG assurance to strengthen self-disciplinary mechanisms within the corporate sector.

In this programme, we map and examine local labour market programmes (LLMPs) at the municipal level in Sweden. This includes their institutional structure and organisation, as well as the experiences of participants in the programmes, using a longitudinal approach with the aim to improve LLMPs. The long-term goal is to increasing the inclusion of LLMP participants in working life. To answer the programme's questions, data will be collected and analysed within the four work packages. In each work package, a mixed-method approach is applied with a combination of quantitative and qualitative methods. The programme is informed by three overarching general theoretical approached, tying together institutional ethnography, intersectional studies of structural inequalities on different levels, and the role of emotions in everyday work. At the organisational level (WP 1), we will investigate the circumstances under which LLMPs are performed and negotiated by those involved. Here, the internal organisation, activities and methods are the focus. This approach will result in knowledge about the characteristics of these organisations and the factors promoting the inclusion of underrepresented groups in working life. By examining the activities in LLMPs (WP 2), we will be able to determine how their institutional structure differs between regions in Sweden, how the different municipalities work with labour market policy, how they translate national policy into the local context, how they organise their work and which initiatives they choose to adopt. By examining the individual experiences of those who are directly affected by such incentives (WP 3), knowledge and understanding will be obtained of the connections between experiences and labour market policies. This will give important insights into the functioning of local programmes and of the opportunities to create entry into the labour market. Furthermore, in WP4 we will develop and test an effect evaluation of work methods used in LLMPs and their effect on clients' progress over time.

ObjectiveTo investigate the possible connection between cardiorespiratory fitness (CRF) and muscle strength in early adulthood and severity of COVID-19 later in life.DesignProspective registry-based cohort study.Participants1 559 187 Swedish men, undergoing military conscription between 1968 and 2005 at a mean age of 18.3 (SD 0.73) years.Main outcome measuresHospitalisation, intensive care or death due to COVID-19 from March to September 2020, in relation to CRF and muscle strength.ResultsHigh CRF in late adolescence and early adulthood had a protective association with severe COVID-19 later in life with OR (95% CI) 0.76 (0.67 to 0.85) for hospitalisation (n=2 006), 0.61 (0.48 to 0.78) for intensive care (n=445) and 0.56 (0.37 to 0.85) for mortality (n=149), compared with the lowest category of CRF. The association remains unchanged when controlled for body mass index (BMI), blood pressure, chronic diseases and parental education level at baseline, and incident cardiovascular disease before 2020. Moreover, lower muscle strength in late adolescence showed a linear association with a higher risk of all three outcomes when controlled for BMI and height.ConclusionsPhysical fitness at a young age is associated with severity of COVID-19 many years later. This underscores the necessity to increase the general physical fitness of the population to offer protection against future viral pandemics.

Brown adipose tissue (BAT) thermogenesis affects energy expenditure, as well as glucose and lipid clearance. Thus, making BAT an attractive target in obesity/type-2 diabetes. Adiponectin (Apn) regulates whole-body metabolism and lowered Apn levels are associated with obesity and increased type-2 diabetes risk. Apn has been suggested to be required for maintaining normal body temperature in cold environment, but the role of Apn in BAT functionality is not clear. Here, we have studied BAT in adiponectin overexpressing (Apn-Tg) mice. During unchallenged chow-diet conditions, BAT of Apn-Tg mice was enlarged, fibrotic and more whitish. This phenotype was, as judged by tracer experiments, associated with lower lipid and glucose uptake, decreased de novo lipogenesis and decreased fatty acid oxidation in BAT. High-fat diet (HFD)-induced obesity increased these differences between genotypes. The BAT mRNA expression of thermogenesis markers such as UCP-1 and DIO-2 were down-regulated in BAT of obese, but not lean, Apn-Tg mice. Moreover, Seahorse-based analysis revealed reduced mitochondrial function in Apn-Tg BAT in ex vivo-differentiated brown adipocytes. To test whether increased Apn levels affect cold-induced BAT activation, we exposed Apn-tg and littermate control mice to cold temperature (6°C) for four weeks. Under this setting, the BAT lipid and glucose uptake, and body temperature were similar between genotypes. Accordingly, UCP-1 and DIO-2 mRNA levels were not different between Apn-Tg and WT mice, and highly induced by chronic cold exposure. Nevertheless, Seahorse data from isolated BAT mitochondria from cold-exposed animals still indicate mitochondrial dysfunction in Apn-Tg mice. Thus, our data suggest that increased adiponectin levels are associated with metabolic dysfunction in BAT. We propose that the increased BAT expansion in Apn-Tg mice occurs at the expense of the mitochondrial function. Disclosure B. Chanclon: None. M. Bauza-Thorbrugge: None. A. Benrick: None. I. Wernstedt-Asterholm: None.

Femtosecond laser-induced spatial redistribution of silver species (ions, clusters, and hole centers) in a silver-containing phosphate glass is investigated by correlative means of near-field scanning optical microscopy (NSOM) images, numerical simulations, chemical micro-probe analysis, and nanoscale spatial profiles after soft etching. In particular, we found that the chemical etching selectivity for nanoscale patterning is strongly dependent upon the irradiation of femtosecond laser due to the spatial redistribution of silver species within the affected area. These results strongly indicate that controlling the distribution of silver species by femtosecond laser irradiation may open new routes for surface nanoscale chemical and/or spatial patterning for the fabrication of 2D surface photonic crystals.

Purpose The aim of this study has been to explore learning experiences from the two first years of the implementation of value-based healthcare (VBHC) at a large Swedish University Hospital. Design/methodology/approach An explorative design was used in this study. Individual open-ended interviews were carried out with 19 members from four teams implementing VBHC. Qualitative analysis was used to analyse the verbatim transcripts of the interviews. Findings Three main themes pinpointing learning experiences emerged through the analysis: resource allocation to support implementation, anchoring to create engagement and dedicated, development-oriented leadership with power of decision. Resource allocation included the need to set aside time and administrative resources and also the need to adjust essential IT-systems. The work of anchoring to create engagement involved both patients and staff and was found to be a never-ending task calling for deep commitment. The hospital top management's explicit decision to implement VBHC facilitated the implementation process, but the team leaders' lack of explicit management mandate was experienced as obstructing the process. The development process contributed not only to single-loop learning but also to double-loop learning. Originality/value Learning experiences drawn from implementing VBHC have not been studied before, and thus the results of this study could be of importance to managers and administrators wanting to implement this concept in their respective organizations.

Introduction: These analyses were conducted to evaluate the time course of heartburn (HB) symptom improvement in subjects treated with esomeprazole (ESO) at the over-the-counter (OTC) dose (20 mg) and duration (14 days). Methods: Individual subject data from the first 14 days were pooled for adults with frequent HB assigned to ESO 20 mg (n=921; administered as 22.3 mg esomeprazole magnesium trihydrate) or placebo (n=909) during 6 similarly designed randomized, double-blind clinical trials conducted at US gastroenterology centers. The daily occurrence and intensity of HB (rated as none, mild, moderate or severe) were recorded in subject daily diaries. Results: Improvement in overall HB frequency, measured as percentage of HB-free 24-hour days across 14 days, was significantly greater for ESO 20 mg compared with placebo (p < .0001). On day 1, significantly more subjects had no episodes of 24-hour HB with ESO 20 mg (32.1%) compared with placebo (17.3%; p < .0001). Across all subjects, the average intensity for 24-hour HB episodes was significantly reduced or diminished for subjects receiving ESO 20 mg compared with placebo starting at day 1 and continuing throughout the 14-day assessment period (p < .0001). The majority of the improvement in 24-hour HB intensity that was observed with ESO 20 mg occurred from day 1-4 (mean [SD] change: -0.71 [0.91]; p < .0001 vs placebo). Significantly more subjects treated with ESO 20 mg compared with placebo had improvements in HB intensity (relative to baseline), and fewer had worsening, beginning on day 1 (64.7% vs 50.6% with improvement, respectively; p < .0001) and extending to day 14 (81.5% vs 64.2% with improvement, respectively; p < .0001). Conclusion: Treatment with ESO at the OTC dose (20 mg) and treatment duration (14 days) significantly reduced the frequency and intensity of HB, with significant improvement in HB occurring on the first day of treatment. Maximal symptom improvement occurred during the first few days of treatment.