Cantonal and University Library of Lausanne

Gastric cancer primarily affects the elderly, but surgical management varies with age. This multicenter, retrospective cohort study assessed treatment approaches and outcomes in patients with gastric cancer based on age. Between 2007 and 2017, 2,131 patients treated in French Surgical Association centers were identified. Patients with metastatic disease, those who did not undergo gastrectomy, those who underwent emergency surgery, those who underwent hyperthermic intraperitoneal chemotherapy, and those with unspecified birth dates were excluded. The final cohort of 1,426 patients was divided into 3 age groups: younger than 70 years (group 1, 60%), 70 to 79 years (group 2, 27%), and 80 years or older (group 3, 13%). Elderly patients were more often women and received less neoadjuvant chemotherapy (58% vs 43% vs 17%, p < 0.001). Despite similar tumor locations, they underwent fewer total gastrectomies (68% vs 55% vs 43%, p < 0.001) and D2 dissections (22% vs 22% vs 12%, p = 0.007). Medical complications increased with age, whereas surgical complications were not significantly higher in group 3. Advanced age was not an independent risk factor for severe postoperative complications (Clavien-Dindo grade III or higher). Pathologic results were comparable, but elderly patients received less postoperative treatment (67% vs 45% vs 16%, p < 0.001). Five-year overall survival decreased with age (64% vs 52% vs 37%, p < 0.001), whereas cancer-specific survival remained stable (69% vs 67% vs 63%, p = 0.56). Advanced age does not independently increase the risk of postoperative morbidity and should not justify less aggressive surgery. Despite receiving less perioperative treatment, selected elderly patients maintain a comparable cancer prognosis to younger individuals.

L’article revisite l’histoire du tournant urbain de l’écologie scientifique depuis les années 1970 en s’intéressant en particulier à la recherche naturaliste dans le contexte suisse. Il s’appuie sur une analyse systématique et qualitative d’un corpus de 450 publications de revues de sociétés naturalistes locales suisses (1839-2018). L’analyse diachronique, centrée sur la co-production entre les savoirs naturalistes et l’objet urbain, montre les continuités et discontinuités de l’intérêt naturaliste pour la ville. Elle conduit à distinguer deux périodes dans les inventaires floristiques locaux : le tournant du XXe siècle (marqué par l’étude des plantes adventices) et les années 1980-1990 (dominé par un intérêt pour la flore urbaine). En explorant les dimensions spatiales de la recherche naturaliste locale, l’article réexamine ainsi le rôle historique joué par l’inventaire naturaliste dans l’émergence d’un intérêt écologique savant pour la ville.

The importance of Deleuze and Deleuze and Guattari's development of ‘encounter’ is brought into sharp relief as key to the notion of ‘athleticism’. Here, each is developed as indispensable to the other, forming an a-radical/ana-material groundless ground to power, politics, literary sensibility, indeed sense itself. This nuanced encounter produces an acephaletic knowledge, a body-knowledge, without the Ego-I. In an age of massifying systems, drone warfare and horrific migrations, where corporate tentacles bend the rules akimbo, one finds that this turn to a Deleuzian athleticism offers a different kind of political analysis, a radical difference, which, despite (or because of) the odds, enables a politics of hope and indeed, of a ‘becoming-human’.

Donner la parole, c’est permettre à la vérité de chacun d’apparaître comme la vérité d’une communion.Michel de Certeau (1964) Pour la définition de « science », le Petit Larousse 2005 propose : « Sciences humaines : disciplines ayant pour objet l’homme et ses comportements individuels et collectifs, passés et présents ». À propos des « Sciences humaines », L’Encyclopœdia universalis fait mention du lien entre ces sciences et une « utopie sociale ». Ces deux définitions rappelées, comment les ...