Centre Hospitalo-Universitaire Dr Benbadis Constantine

Musculoskeletal ultrasound has become an essential tool in the management of rheumatoid arthritis (RA), particularly for early diagnosis, assessment of disease activity, treatment monitoring, and decision-making during remission. It also contributes to improving the accuracy of interventional procedures. In Maghreb countries, its use has expanded significantly through local and international training initiatives. In this article, the Maghreb Committee of Experts in Rheumatologic Imaging (CEMIR) proposes practical recommendations, tailored to the regional context, to optimize the use of ultrasound in RA at all stages of patient management.

A eight-year-ol d child from the Constantine region with no significant medical history was admitted due to progressive weakness in the lower limbs over a period of approximately 20 days, accompanied by difficulty walking.What is your diagnosis?

Epileptic spasms associated with tuberous sclerosis complex (TSC) are associated with poor epileptic and cognitive prognosis [1,2]. Knowledge of prognostic factors makes it possible to improve its management. We report the clinical, electrical, renal ultrasound, brain MRI and neurocognitive profile of this drug-resistant epilepsy. During the 5-year study period, five patients were diagnosed with TSBdue to the association of epilepsy with Infantile Epileptic Spasm Syndrome (IESS), achromic spots, cortical tubes and renal cysts in all patients. The clinical symptoms of seizures with types of epileptic spasms, associated with partial or generalized seizures and the EEG: atypical hypsarrhythmia or focus of spikes and slow waves localized to lesional foci of the tubers. Brain MRI shows cortical tubes with subependymal nodules. Two out of five patients, late onset of epilepsy at 18 and 2 years old, had good electro-clinical control of epilepsy with a better cognitive and behavioral score. The others started their epilepsy before a year or unsuitable treatment of spasms. evolved into drug-resistant epilepsy, with a neuro-cognitive-behavioral deficit, an 8-year-old patient with drug-resistant epilepsy had a spectacular improvement under Rapamycin. Our conclusion is that early diagnosis and treatment, Rapamycin and Antenatal and neonatal diagnosis with antiepileptic drugs in front of a pathological EEG, could improve epilepsy and associated comorbidities.