Cerbomed (Germany)

Article Cancik-Kirschbaum, Eva / Gertzen, Thomas L. (Hg.): Der Babel-Bibel-Streit und die Wissenschaft des Judentums. Beiträge einer internationalen Konferenz vom 4. bis 6. November 2019 in Berlin. Münster: Zaphon 2021 (= Investigatio Orientis 6). € 58,00. ISBN 978-3-96327-098-7. was published on December 31, 2024 in the journal Orientalistische Literaturzeitung (volume 119, issue 3).

Article Krisel, William: Judges 19–21 and the “Othering“ of Benjamin. A Golah Polemic against the Autochthonous Inhabitants of the Land?. Leiden/Boston: Brill 2022. XIV, 448 S. 8° = Oudtestamentische Studiën 81. Hardbd. € 138,00. ISBN 978-90-04-49934-8. was published on December 3, 2023 in the journal Orientalistische Literaturzeitung (volume 118, issue 6).

Article Von Kügelgen, Anke (Hg.): 19. und 20. Jahrhundert: 1. Arabischer Sprachraum. 2. Türkei, Iran und Südasien. Basel: Schwabe 2021. LVIII, 1480 S. 8° = Philosophie in der islamischen Welt 4. Lw. € 460,00. ISBN 978-3-7965-2839-2. was published on December 1, 2023 in the journal Orientalistische Literaturzeitung (volume 118, issue 3).

Abstract Membrane bound histidine kinases (HKs) are ubiquitous sensors of extracellular stimuli in bacteria. Here, we used solid-state NMR in conjunction with crystallography, solution NMR and distance measurements to investigate the transmembrane signaling mechanism of a paradigmatic citrate sensing membrane embedded HK, CitA. Citrate binding in the sensory extracytoplasmic PAS domain (PASp) causes the linker to transmembrane helix 2 (TM2) to adopt a helical conformation. This triggers a piston-like pulling of TM2 and a quaternary structure rearrangement in the cytosolic PAS domain (PASc). Crystal structures of PASc reveal both anti-parallel and parallel dimer conformations. An anti-parallel to parallel transition upon citrate binding agrees with interdimer distances measured in the lipid embedded protein using a site-specific19F label in PASc. These data show how Angstrom scale structural changes in the sensor domain are transmitted across the membrane to be converted and amplified into a nm scale shift in the linker to the phosphorylation subdomain of the kinase.One-Sentence SummaryTransmembrane signal transduction of a PAS-domain containing histidine kinase occurs via a piston-like pulling of a transmembrane helix, and amplification by cytoplasmic PAS domain dimer rearrangement.

Article Max Weber, Max Weber-Gesamtausgabe. Bd. III, Teil 2: Praktische Nationalökonomie. Vorlesungen 1895–1899. Hrsg. von Hauke Janssen in Zusammenarbeit mit Cornelia Meyer-Stoll und Ulrich Rummel. Tübingen, Mohr Siebeck 2020 was published on October 1, 2021 in the journal Historische Zeitschrift (volume 313, issue 2).