Compagnia di San Paolo

Despite promising outcomes in higher education, the widespread adoption of learning analytics remains elusive in various educational settings, with primary and secondary schools displaying considerable reluctance to embrace these tools. This hesitancy poses a significant obstacle, particularly given the prevalence of educational technology and the abundance of data generated in these environments. In contrast to higher education institutions that readily integrate learning analytics tools into their educational governance, high schools often harbor skepticism regarding the tools’ impact and returns. To overcome these challenges, this work aims to harness learning analytics to address critical areas, such as school dropout rates, the need to foster student collaboration, improving argumentation and writing skills, and the need to enhance computational thinking across all age groups. The goal is to empower teachers and decision makers with learning analytics tools that will equip them to identify learners in vulnerable or exceptional situations, enabling educational authorities to take suitable actions that are aligned with students’ needs; this could potentially involve adapting learning processes and organizational structures to meet the needs of students. This work also seeks to evaluate the impact of such analytics tools on education within a multi-dimensional and scalable domain, ranging from individual learners to teachers and principals, and extending to broader governing bodies. The primary objective is articulated through the development of a user-friendly AI-based dashboard for learning. This prototype aims to provide robust support for teachers and principals who are dedicated to enhancing the education they provide within the intricate and multifaceted social domain of the school.

Compagnia di San Paolo, an Italian grantmaking foundation, conducted a text analysis using a set of keywords extracted from grantees’ project descriptions to measure how successfully its work aligned with the United Nations’ 17 Sustainable Development Goals, and to identify interrelationships among the goals themselves. This article describes the foundation’s research methods and shares the results of its analysis, which found significant contributions to the goals in a number of areas funded by the Compagnia and less alignment in others. The analysis is particularly noteworthy in its identification of an unintentional pattern of convergence between the foundation’s activities and the Sustainable Development Goals, which were never explicitly adopted by the foundation as terms of reference in any aspect of the planning and development of its work. To understand how a foundation’s work aligns with the Sustainable Development Goals framework is useful to many philanthropic functions: communication; advocacy; offering a role in a common, worldwide effort; and evaluating the organization’s own choices (explicit or tacit) against the background set by the project. This article illustrates how other foundations can adapt Compagnia’s approach to evaluate their own contributions.

An 11-month-old girl with B-cell leukemia/lymphoma developed profound lethargy due to severe lactic acidosis during chemotherapy and total parenteral nutrition (TPN). Initial treatment with NaHCO3 was ineffective. Treatment with a vitamin cocktail (OH-cobalamin, pyridoxine, thiamine, riboflavine, biotin, carnitine) at pharmacologic doses rapidly improved the child's clinical and laboratory status. Lactic acidosis was caused by an impairment of pyruvate dehydrogenase complex, which was due to lack of its necessary cofactor thiamine in the TPN. This case report indicates that lactic acidosis may be a front-line diagnosis in patients on TPN with lethargy and outlines the need for monitoring thiamine supply in TPN.