Dempsey (Canada)

This study investigates how reference staff at two libraries balance teaching with resource delivery in live chat reference. Analysis of 410 transcripts from one week shows that one library tends to deliver more resources from a wider range of database suggestions, to take more time in chat interactions, and to incorporate more teaching behavior with specific resource links. Two possible reasons for these differences are reference policies and staffing models: one library states that chat is for brief factual questions and monitors chat from a public service point; the other does not state a policy and monitors chat from private offices. Findings are important for staffing responsively, developing effective research guides, and improving teaching in online reference.

Background: Metabolic dysregulation associated with aging impacts stroke incidence and outcome. Hyperglycemia occurs in 30% of patients with ischemic stroke, and is associated with poor stroke recovery. On the other hand, depletion of glucose within the brain prevents production of ATP, leading to energy reduction and neuronal death. Thus, balanced glucose metabolism is critical for normal brain function. However, our understanding of the regulation of genes involved in glucose metabolism and relationship to age in the post-stroke brain is elusive. Methods: Using transcriptomic and metabolomics approach, we examined the expression pattern of glucose metabolism pathway specific genes in the naïve and post-stroke brains of 3 month, and 12 month old rats subjected to focal cerebral ischemia by middle cerebral artery occlusion and 2 days re-perfusion. Metabolites were analyzed using Nuclear Magnetic Resonance (NMR) spectroscopy. Results: Our data shows substantial alterations in the glucose metabolism pathway in aged, and particularly in post stroke rat brain. Brains from 12 month old rats showed about 15 fold increase in phosphoenolpyruvate carboxykinase (PCK1), and 2 fold increase in phosphorylase kinase (PHKG1) mRNA as compared to 3 month old rats. In the post-stroke brain, mRNA levels of hexokinase 3 (HK3) was upregulated 9 fold in 3 month old rats. However, HK3 mRNA substantially increased to 26 fold in 12 month old post-stroke brain as compared to control brains. The PCK1 gene was down regulated 2-4 fold in post-stroke brain. Metabolomics studies indicated significant alterations in nucleotide metabolism and decreased antioxidants in the aged brain. Metabolic changes in post-stroke brains included depletion of ADP and AMP, and accumulation of fumarate, O-phospho-ethanolamine, glycerol, glycine, leucine, lysine and malate. Conclusion: Upregulation of PCK1, a key gluconeogenic enzyme may contribute to excess glucose production in aged brain, leading to increased risk of obesity and stroke. The inducible expression of HK3 in post-stroke brain suggests its adaptive role in metabolic responses to stress in the ischemic environment. Overall, HK3 by modulating glycolysis pathway, may lead to metabolic reprogramming in aged and post stroke brain.

Research Article| June 01 2011 Regulating the U.s. Health Care System: Failure in Motion Peter D. Jacobson; Peter D. Jacobson Search for other works by this author on: This Site Google Laura M. Napiewocki; Laura M. Napiewocki Search for other works by this author on: This Site Google Leah A. Voigt Leah A. Voigt Search for other works by this author on: This Site Google J Health Polit Policy Law (2011) 36 (3): 583–589. https://doi.org/10.1215/03616878-1271306 Cite Icon Cite Share Icon Share Twitter Permissions Search Site Citation Peter D. Jacobson, Laura M. Napiewocki, Leah A. Voigt; Regulating the U.s. Health Care System: Failure in Motion. J Health Polit Policy Law 1 June 2011; 36 (3): 583–589. doi: https://doi.org/10.1215/03616878-1271306 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsJournal of Health Politics, Policy and Law Search Advanced Search The text of this article is only available as a PDF. © 2011 by Duke University Press2011 Article PDF first page preview Close Modal Issue Section: Part VII: The Need for More Reform You do not currently have access to this content.

The EC Social Charter, Professional Standards, and New Engineering Entrants Brian Harnett; Brian Harnett Squire, Sanders and Dempsey Search for other works by this author on: This Site Google Scholar Simon Taylor Simon Taylor Squire, Sanders and Dempsey Search for other works by this author on: This Site Google Scholar Paper presented at the SPE Annual Technical Conference and Exhibition, Dallas, Texas, October 1991. Paper Number: SPE-22609-MS https://doi.org/10.2118/22609-MS Published: October 06 1991 Cite View This Citation Add to Citation Manager Share Icon Share Twitter LinkedIn Get Permissions Search Site Citation Harnett, Brian, and Simon Taylor. "The EC Social Charter, Professional Standards, and New Engineering Entrants." Paper presented at the SPE Annual Technical Conference and Exhibition, Dallas, Texas, October 1991. doi: https://doi.org/10.2118/22609-MS Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll ProceedingsSociety of Petroleum Engineers (SPE)SPE Annual Technical Conference and Exhibition Search Advanced Search THE EC SOCIAL CHARTER AND THE MUTUAL RECOGNITION OF PETROLEUM ENGINEERSIntroductionThe aim of this paper is first, to give a brief overview of the EC Social Charter highlighting its achievements to date and second, to focus on the Community's attempts to harmonize the divergent national rules governing professional standards and the recognition of diplomas with emphasis on the engineering sector.The Social Charter seeks to establish a code of fundamental social rights to be enjoyed by Community workers. However it is no more than a political declaration of principles and intent. It has no legislative effect nor does it extend the legislative powers of the Community Institutions. powers of the Community Institutions. Indeed it was signed by only eleven out of twelve Member States. The United Kingdon, under Margaret Thatcher's intransigent leadership, refused to approve a document which it saw as an attempt by European socialists such as Jaques Delors, the President of the Commission and Vasso Papandreou, the EC Social Affairs Commissioner, to introduce socialism "by the back door" thus undermining the U.K.'s duly elected conservative government.Although the mutual recognition of diplomas and professional experience was listed in the Social Charter as a fundamental social right, it is easily distinguished from many of the other, more politically controversial, rights. It will be seen below that the central idea behind the Social Charter is to protect workers from the cut-throat capitalism of the free-market system by creating a safety net of workers' rights. Its opponents see it as a socialist threat to the success of the EC "single market" programme which is due to be completed by 1992. The recognition of diplomas is, on the other hand, a central aspect of the EC rules governing the free movement of persons in the Community. The Treaty of Rome, which is the constitution of the European Community, obliges member states to ensure that persons, including workers and professionals, can move freely and establish themselves without hindrance anywhere in the Community. This principle, along with the free movement of goods, services and capital, is a prerequisite to the success of the EC "single market." The idea is without this freedom of movement throughout the Community the desired pan-European economies of scale cannot be achieved. For example, and engineering firm, based in one member state but wishing to branch out and operate throughout the Community, would suffer a commercial handicap if its engineers, qualified in the original member state were unable to offer their professional services or be relocated in other Member States. Keywords: legislation, member state, health & medicine, diploma, qualification, directive, host state, social charter, mutual recognition, professional qualification Subjects: Professionalism, Training, and Education This content is only available via PDF. 1991. Society of Petroleum Engineers You can access this article if you purchase or spend a download.