Essilor (Germany)

The crucial role of coastal wetlands supporting diverse terrestrial wildlife is often asserted but has not been demonstrated in broad-scale field evaluations; a comprehensive assessment of wildlife use of these vital habitats is therefore needed. Our

Abstract The Geneva Conventions invite the parties to a non-international armed conflict (NIAC) to conclude special agreements (SAs) according to common Article 3(3). However, the lack of definition and insufficient coverage of such agreements by scholars and legal authorities increase the confusion between that mechanism and other agreements occurring in NIACs. This paper offers a contemporary and functional definition of SAs in order to better demonstrate their importance for NIAC regulation based on practice-informed lessons and, incidentally, to advocate for an increased use of those instruments. The data analyzed throughout this article reveal various lessons that will illustrate the potential of SAs. Among the teachings revealed by practice is the expanded material scope of these instruments or the possible ways in which the parties can choose to draft their commitments. In addition, the records of practice reveal how SAs concretely improve the regime of NIACs, and the implementation approaches generally adopted. For a more complete study of the dynamics of SAs, the paper equally draws attention to their formal and personal characteristics. All these features turn SAs into powerful international humanitarian law (IHL) tools that are flexible enough to upgrade the applicable law of NIACs while respecting some necessary boundaries in order to guarantee the validity of the obligations embedded. This is an essential balance for IHL and international legal order consistency.

Se analizaron las variaciones espaciales y temporales del índice de calidad del agua en las tres capas de estratificación térmica en un cuerpo de agua endorreico de Michoacán, México. Se utilizaron dos métodos, el primero es el desarrollado por la Fundación Nacional de Saneamiento de los Estados Unidos de América, que usa nueve variables, físicas, químicas y bacteriológicas, para la estimación del índice. El segundo usa tres parámetros que son recomendados por la Comisión Nacional del Agua en México. El conjunto de datos analizado es una base de datos pública con información de los años 2012 a 2019 en cuatro sitios de muestreo. Los resultados mostraron que la calidad del agua del lago es buena y que en los meses en los que se rompe la estratificación térmica la calidad del agua en el lago es ligeramente mejor que la registrada en los meses de estratificación térmica.

Abstract There is a growing need to develop ways of assessing cognitive functions remotely and providing interventions using a web-based approach. The Ipsilon Test is a music-based cognitive assessment and training tablet application. On each trial, it presents simplified musical notation with colours, spatial cues, and gestural references so that users can translate spatial information into motor actions by tapping on the screen. In this study, we examined the correlation between the performance of a group of healthy older adults on the Ipsilon test and standard measures of cognitive function—a total of 30 participants aged 58 and over were recruited for the study. Before and after one week of training using the web-based program Ipsilon, all participants completed an online version of the Montreal Cognitive Assessment (MoCA) and the visual Stroop task. Of the participants recruited, 22 participants completed the Ipsilon training and cognitive testing. In our sample, performance on the Ipsilon test was generally high, with all participants scoring above the chance level. Importantly, we found a correlation between Ipsilon test performance and pre-Ipsilon MoCA scores. In addition, participants who scored higher on the Ipsilon test also showed improvement in the visual Stroop task after Ipsilon training, particularly in the ability to inhibit irrelevant information. These results suggest the Ipsilon test is a practical web-based cognitive assessment and training tool. Future research will explore its relationship with other cognitive tests and its diagnostic power for differentiating individuals with normal cognition from those with cognitive disorders.

Abstract A new concept of battery doctor is proposed for the next generation battery health assessment, first, the comprehensive assessment framework integrating the multiple health indices is formulated, where the bottom‐up assessment hierarchy is used to provide the holistic health indicator from the battery cell to the large‐format battery. Second, several options for defining a uniform indicator state of X is provided to effectively measure the battery health, which contributes to promoting the health assessment from state of charge and stage of health to state of X. Finally, the future challenges and opportunities of developing the battery doctor are disclosed from three different viewpoints, which is to incentivize the technology breakthrough for the next generation battery health assessment.

This chapter aims to estimate the myopia among school children of Bangalore region, Karnataka, India. Myopia is one of the most common visual problems that affects both children and adults. High myopia increases the risk of developing irreversible vision loss due to pathologic changes in the retina, as well as the risk of glaucoma, cataract, and amblyopia. The current study included students aged 5 to 15 years from urban and rural schools in the Bangalore region. A total of 3038 students were screened from six different schools, with 1510 girls and 1528 boys. The students were subjected to basic eye examinations such as visual acuity and dry retinoscopy. In addition, the power of the glasses the children were already wearing for the past correction was recorded. According to the findings of this study, 4% (241) of the 6076 eyes screened had myopia. Myopia affected 3.18% (94) of 2954 rural children and 4.71% of 3122 urban children. It was concluded that urban school children in Bangalore, Karnataka, had a higher frequency of myopia than rural school children.

AimsTo evaluate the 1-year efficacy of two new myopia control spectacle lenses with lenslets of different asphericity.MethodsOne hundred seventy schoolchildren aged 8–13 years with myopia of −0.75 D to −4.75 D were randomised to receive spectacle lenses with highly aspherical lenslets (HAL), spectacle lenses with slightly aspherical lenslets (SAL), or single-vision spectacle lenses (SVL). Cycloplegic autorefraction (spherical equivalent refraction (SER)), axial length (AL) and best-corrected visual acuity (BCVA) were measured at baseline and 6-month intervals. Adaptation and compliance questionnaires were administered during all visits.ResultsAfter 1 year, the mean changes in the SER (±SE) and AL (±SE) in the SVL group were −0.81±0.06 D and 0.36±0.02 mm. Compared with SVL, the myopia control efficacy measured using SER was 67% (difference of 0.53 D) for HAL and 41% (difference of 0.33 D) for SAL, and the efficacy measured using AL was 64% (difference of 0.23 mm) for HAL and 31% (difference of 0.11 mm) for SAL (all p<0.01). HAL resulted in significantly greater myopia control than SAL for SER (difference of 0.21 D, p<0.001) and AL (difference of 0.12 mm, p<0.001). The mean BCVA (−0.01±0.1 logMAR, p=0.22) and mean daily wearing time (13.2±2.6 hours, p=0.26) were similar among the three groups. All groups adapted to their lenses with no reported adverse events, complaints or discomfort.ConclusionsSpectacle lenses with aspherical lenslets effectively slow myopia progression and axial elongation compared with SVL. Myopia control efficacy increased with lenslet asphericity.Trial registration numberChiCTR1800017683.

Background/aimsTo evaluate the predictive performance of various predictors, including non-cycloplegic refractive error, for risk of myopia onset under pragmatic settings.MethodsThe Wenzhou Medical University Essilor Progression and Onset of Myopia Study is a prospective cohort study of schoolchildren aged 6–10 years from two elementary schools in Wenzhou, China. Non-cycloplegic refraction, ocular biometry and accommodation measurements were performed. Myopia was defined as spherical equivalent (SE) ≤−0.5 diopter (D). ORs using multivariable logistic regression were determined. Area under the curve (AUC) evaluation for predictors was performed.ResultsSchoolchildren who attended both baseline and 2-year follow-up were analysed (N=1022). Of 830 non-myopic children at baseline, the 2-year incidence of myopia was 27.6% (95% CI, 24.2% to 31.3%). Female gender (OR=2.2), more advanced study grades (OR=1.5), less hyperopic SE (OR=11.5 per D), longer axial length (AL; OR=2.3 per mm), worse presenting visual acuity (OR=2.3 per decimal), longer near work time (OR=1.1 per hour/day) and lower magnitude of positive relative accommodation (PRA; OR=1.4 per D) were associated with myopia onset. PRA (AUC=0.66), SE (AUC=0.64) and AL (AUC=0.62) had the highest AUC values. The combination of age, gender, parental myopia, SE, AL and PRA achieved an AUC of 0.74.ConclusionApproximately one in four schoolchildren had myopia onset over a 2-year period. The predictors of myopia onset include lower magnitude of PRA, less hyperopic SE, longer AL and female gender. Of these, non-cycloplegic SE and PRA were the top single predictors, which can facilitate risk profiling for myopia onset.

Lighting is rapidly changing with the introduction of light-emitting diodes (LEDs) in our homes, workplaces, and cities. This evolution of our optical landscape raises major concerns regarding phototoxicity to the retina since light exposure is an identified risk factor for the development of age-related macular degeneration (AMD). In this disease, cone photoreceptors degenerate while the retinal pigment epithelium (RPE) is accumulating lipofuscin containing phototoxic compounds such as A2E. Therefore, it remains unclear if the light-elicited degenerative process is initiated in cones or in the RPE. Using purified cone photoreceptors from pig retina, we here investigated the effect of light on cone survival from 390 to 510 nm in 10 nm steps, plus the 630 nm band. If at a given intensity (0.2 mW/cm²), the most toxic wavelengths are comprised in the visible-to-near-UV range, they shift to blue-violet light (425–445 nm) when exposing cells to a solar source filtered by the eye optics. In contrast to previous rodent studies, this cone photoreceptor phototoxicity is not related to light absorption by the visual pigment. Despite bright flavin autofluorescence of cone inner segment, excitation–emission matrix of this inner segment suggested that cone phototoxicity was instead caused by porphyrin. Toxic light intensities were lower than those previously defined for A2E-loaded RPE cells indicating cones are the first cells at risk for a direct light insult. These results are essential to normative regulations of new lighting but also for the prevention of human retinal pathologies since toxic solar light intensities are encountered even at high latitudes.