European Union of Medical Specialists

Este artigo explora as significações da água no romance Um rio chamado tempo, uma casa chamada terra (2003), do autor moçambicano Mia Couto. Elemento essencial para a vida terrestre, a água garante a existência e a sobrevivência de todos os seres vivos, e pode ser considerada não apenas um elemento material essencial, mas também simbólico, cujas representações provocam divergências e aproximações entre povos e comunidades de diferentes culturas. O objetivo deste estudo é apresentar as múltiplas significações da água em diferentes contextos histórico-culturais, focando as representações construídas acerca do rio na poética de Mia Couto. Buscaremos sustentação teórica nuclear em Bachelard (1989), a fim de apreender as significações deste elemento sob o viés filosófico-poético. O referido teórico extrapola os limites da simbologia, ao explorar a imaginação criadora e falante, com foco no psiquismo hidrante, ou seja, no pensamento das águas. Por meio do método comparativo, almejamos compreender a relação da água no romance com as significações que residem em distintos cenários histórico-culturais, e contribuir para o entendimento acerca da simbologia da água na narrativa coutiana.

The use of biopotential enhancers in seed treatment can improve germination rates and initial plant development under field conditions, especially when using low-vigor seeds. In this context, this study was conducted to evaluate the emergence and initial growth of soybean seedlings in response to the application of doses of the Crop Evo® biopotential enhancer to seeds with low and high vigor levels. The experimental design used was completely randomized, and the treatments were arranged in a 2 × 5 factorial scheme, with four replications. The treatments consisted of using two seed vigor levels (high and low) and applying five doses of biopotential enhancer (0, 5, 10, 15, and 20 mL kg–1 of seed) to the seeds. Fourteen days after sowing, the percentage of emergence, emergence speed index, mean emergence time, shoot length, and root dry matter production of the seedlings were evaluated. The results showed that the application of a biopotential enhancer (Crop Evo®) in seed treatment improved the emergence and emergence speed of soybean seedlings from low-vigor seeds. However, the application of the biopotential enhancer had no effect on the emergence process of soybean seedlings from high-vigor seeds. The application of the biopotential enhancer in seed treatment stimulated the growth and dry matter production of soybean seedlings, regardless of whether low- or high-vigor seeds were used. The optimal dose of biopotential enhancer to be applied in soybean seed treatment to stimulate initial seedling growth can vary from 10 to 15 mL kg–1 of seed.

This quality improvement study presents the results of the 2025 edition of the European Board Examination in Psychiatry.

The genus Schinus L. includes plants used in folk medicine with important pharmacological effects. However, little is known about Schinus weinmanniifolia Mart. ex Engl. This study evaluated the antioxidant, photoprotective, antimicrobial, and cytotoxic activities of its ethanolic extracts and identified bioactive compounds. Phytochemical analysis confirmed saponins, alkaloids, phenolic compounds, flavonoids, and tannins in leaves, stems, and roots extracts. Syringic acid, epicatechin, and rutin were identified using ultra-performance liquid chromatography with a diode array detector. The leaves extract showed the lowest IC50 in the DPPH method, and all extracts effectively scavenged ABTS radicals, outperforming BHT. All extracts demonstrated sun protection and antimicrobial action against Gram-positive bacteria and yeasts but lacked antiprotozoal activity. They showed no hemolytic potential or cytotoxicity in Vero cells at active concentrations. These findings highlight S. weinmanniifolia as a promising focus for future investigations aimed at further exploring its bioactive properties.

O artigo tem por objetivo mostrar que, em muitos momentos, no fazer pedagógico, os/as professores/as desobedecem ao currículo escolar e que, ao fazerem isso, estão considerando a realidade da escola onde atuam e a singularidade dos/as alunos/as; estão construindo um currículo na relação com todos aqueles que lá estão, potencializando várias novas maneiras de ser. A análise é fruto de pesquisa em que se utilizou entrevista semiestruturada com professores/as de uma escola pública estadual. A análise dos enunciados dos/as professores/as aproxima-se da perspectiva pós-estruturalista e apresenta, primeiramente, contribuições de teóricos como Frédéric Gros, Michel Foucault, Suely Rolnik, Gilles Deleuze e Hannah Arendt, entre outros, para a reflexão/compreensão sobre como, na desobediência/insurgência/revolta contra certas condições históricas, criamos a nós mesmos e as nossas vidas e abrimos possibilidades de condições históricas diferentes. Em um segundo momento, por meio da análise das entrevistas dos/as professores/as, mostramos que, ao desobedecerem ao currículo, eles/as estão potencializando a diferença presente na escola e provocando transformações subjetivas e objetivas que acarretarão formas diferentes de estar no mundo e de relacionar-se com ele, com eles/as mesmos/as e com os outros.

To systematically evaluate the impact of SSRIs on sexual function in adults with depression compared to placebo through a systematic review and meta-analysis of randomized controlled trials (RCTs). A systematic search using the terms "sexual dysfunction", "depression" and "antidepressant" was conducted in PubMed/MEDLINE, LILACS, Embase, and the Cochrane Library for RCTs published up to June 2025. No language restrictions were applied. Both dichotomous and continuous outcomes were analyzed with 95% confidence intervals using RevMan 5.4. The risk of bias in individual studies was assessed independently by two reviewers using the revised Cochrane Risk of Bias tool for randomized trials (RoB 2). Thirteen RCTs met inclusion criteria for qualitative synthesis and six were included in meta-analyses. SSRIs were significantly associated with increased risk of orgasmic dysfunction (RR = 3.28, (95% CI of 2.33 to 4.60, p < 0.00001; I² = 8%,) and reduced sexual satisfaction (RR = 1.21, (95% CI of 1.11 to 1.32, p = 0.0001, I² = 0%,). A non-significant trend toward decreased sexual desire was observed (RR = 1.40, 95% CI: 0.92-2.12, p = 0.12; I² = 54%,). No significant differences were detected in total CSFQ scores compared with placebo. SSRI use is consistently associated with sexual dysfunction, particularly orgasmic dysfunction and reduced sexual satisfaction. The GRADE assessment indicated high to moderate certainty of evidence. Orgasmic dysfunction showed high certainty, with concerns limited to risk of bias. Sexual satisfaction, sexual desire disorders, and CSFQ total scores demonstrated moderate certainty, mainly due to risk-of-bias issues.

Abstract Invasive species can alter ecosystem processes, disrupt food webs, and cause significant economic and health-related impacts. Digitonthophagus gazella , an African dung beetle introduced globally for pasture improvement, exemplifies the ecological risks of biological invasions. In South America, its assisted introduction and subsequent invasion led to significant declines, with some species becoming locally extinct. We aimed to investigate how the abundance (total, females, and males) and morphological traits (body size and horn size) of D. gazella relate to native dung beetle assemblage metrics, including abundance and species richness of the overall assemblage and functional groups. Additionally, we examined how both D. gazella and native dung beetle variables respond to fine-scale climatic conditions in Brazilian pastures where the species has been introduced. Sampling took place over 52 weeks (April 2020–March 2021) in the Cerrado–Pantanal transition zone in Aquidauana, midwestern Brazil, covering both dry and rainy seasons. Our results indicate that the presence of D. gazella was not associated with changes in the overall temporal distribution of native dung beetles, but it was associated with lower abundance of endocoprid species. Native dung beetle abundance increased with temperature, while humidity reduced the total abundance of D. gazella and its females. Temperature also had a positive effect on D. gazella males. Overall, climatic factors were more influential than the presence of D. gazella in driving trait-based filtering of native species over time. The D. gazella case highlights how invasive species can restructure native assemblages, outcompete similar species, and potentially alter ecosystem functions like dung removal and nutrient cycling.

O objetivo desta pesquisa foi analisar o processo de urbanização do município de Bonito (MS), considerando sua relação com a atividade turística, a partir de uma abordagem do espaço geográfico. A metodologia incluiu pesquisa documental e bibliográfica, análise de dados econômicos RAIS, do IDHM e fluxos turísticos do OTEB (2021-2022). O aumento do fluxo turístico em Bonito, a partir de 1993, foi impulsionado por ações midiáticas. Em resposta, foram criados diplomas legais para organizar a atividade e capacitar profissionais, o que resultou no crescimento da oferta de serviços e empregos turísticos. Os serviços turísticos passaram a atender à demanda efetiva de visitantes. Os principais emissores de turistas para Bonito são grandes centros urbanos, com destaque para São Paulo e Rio de Janeiro, responsáveis pela maior parte do fluxo para o aeroporto.

Acute Compartment Syndrome (ACS) is a frequent complication in polytraumatized patients, characterized by increased intracompartmental pressure in affected organs or limbs. When failed to identify and treat early, it may progress to ischemia, tissue necrosis, muscle impairment, limb amputations and even death. This condition is more prevalent among patients admitted to Intensive Care Units (ICUs). This study aimed to review the clinical manifestations of ACS in children, its main predisposing factors, the therapeutic strategies used and their effectiveness, with an emphasis on critical polytrauma cases. An integrative literature review was conducted using SciELO, LILACS, and PubMed databases. For material selection, the recency and thematic relevance of publications was considered, including articles from the last 5 to 10 years addressing ACS in the context of pediatric polytrauma. The findings indicated that the main causative agents include high-energy trauma, fractures, extensive burns and envenomation by poisonous animals. In children, early diagnosis is essential, but may be hindered by limitations in communication and atypical clinical presentation. Fasciotomy is considered the most effective treatment, with outcomes directly related to the timing of the intervention; however, complications such as infections, nerve injuries, and tissue damage are common. It's concluded that the management of pediatric ACS requires a multidisciplinary approach, emphasizing early detection of clinical signs and a prompt response from a well-trained healthcare team. The implementation of specific protocols and the use of biomarkers may significantly contribute to timely diagnosis and improved outcomes, minimizing the risk of permanent sequelae and reducing mortality.