Faculdade Sumaré

Objetivo: analisar a mortalidade por NMM em mulheres (≥ 20 anos) residentes no Piauí de 2010 a 2023. Metodologia: estudo transversal e ecológico com do Sistema de Mortalidade tabulados via Tabwin. Foi analisado a distribuição espaço-temporal e perfil epidemiológico. Calculou-se as taxas por 100.000 pelo Excel, confeccionou-se os mapas com número de casos por municípios e calculou-se o teste Qui-quadrado de Pearson com significância de 5%. Resultados: foram registrados 2.617 óbitos por NMM no Piauí. Verificou-se aumento nas taxas de mortalidade (12,5 a 17,6%), maior concentração de óbitos nos municípios mais populosos, elevadas proporções de mulheres com 50 a 59 anos (25,8%), pardas (58,9%) e casadas (37,6%). Observou-se significância estatística com todas as variáveis analisadas entre adultas e idosas. Conclusão: A mortalidade por CMM apresentou distribuição temporal crescente, concentrada em municípios populosos e com fatores sociodemográficos proporcionalmente elevados e estatisticamente significativos quando comparados entre grupos etários distintos.

New Minimally Invasive Surgical Techniques in Vascular Surgery: Systematic Review of the Literature" provides a comprehensive analysis of minimally invasive surgical techniques in vascular surgery, highlighting the promising outcomes obtained in comparison to traditional approaches. Based on the systematic review of 18 selected studies, it is evident that these techniques have yielded significant benefits, including shorter hospital stays, faster recovery times, and a lower incidence of postoperative complications. Endovascular surgery emerges as a safe and effective option for abdominal aortic aneurysms and peripheral arterial disease, demonstrating lower morbidity and mortality compared to open surgery. The evolution to endovascular endarterectomy has shown positive results in carotid stenosis cases, yielding reduced hospitalization time and morbidity. The hybrid approach also holds promise in complex cases, combining endovascular lesions and open surgery for favorable outcomes. However, challenges such as the requirement for specialized equipment and rigorous training persist. The summary underscores the efficacy and safety of minimally invasive techniques in vascular surgery, advocating for ongoing research to refine existing approaches and develop novel alternatives that benefit patients.

Introduction: Monkeypox is a rare, viral and emerging disease, although in recent months it has become a growing concern for health professionals and public health authorities around the world. The disease is caused by an orthopoxvirus of the same genus as the human smallpox virus and can cause serious complications in both humans and animals. Objective: To show, through the scientific literature, the complications of monkeypox. Methodology: This is an integrative literature review research, carried out between the months of May and July 2023, through a survey of data in the scientific bases of health: LILACS and SCIELO. Results and Discussion: Through the analysis of the selected studies, the main information for the discussion of this study was evaluated. Scientific evidence has shown that monkeypox complications can vary according to the severity of the patient and can affect different systems of the human body. The scientific literature has pointed out that the main complications of monkeypox include skin infections and skin abscesses. In addition, infection with the virus can provoke the development of cardiac complications, such as myocarditis and heart failure. It can cause abnormal heart rhythms and other cardiovascular problems. Monkeypox develops more severely in people with weakened immune systems because the body has difficulty controlling viral replication. In such cases, the infection can spread quickly and affect various organs and systems in the body. Conclusion: Complications of monkeypox pose significant public health and safety challenges. Although the disease is less lethal than smallpox in humans, it can cause serious complications in infected patients, with localized cutaneous effects such as pustule formation and secondary infections, as well as systemic effects affecting vital organs and body systems.

Introdução/contextualização: O Ensino Fundamental I é a fase mais relevante da escolarização da criança tendo em vista de que é o momento em que se consolida seu desenvolvimento colocando em prática as habilidades necessárias para a apreensão da escrita, da leitura e das operações matemáticas básicas. É nesse período de aprendizagens que se evidenciam as peculiaridades do aprender de cada criança, peculiaridades estas que também são externadas por meio da dificuldade na apropriação dos conteúdos propostos e que se demonstram no baixo rendimento acadêmico e dão origem a questionamentos quanto a capacidade de aprender da criança. Objetivo: Este trabalho experimental se propõe a discorrer sobre o processo de avaliação neuropsicopedagógica, a identificação dos fatores que interferem no processo de aprendizagem do sujeito aprendente e demonstrar a relevância deste profissional, o neuropsicopedagogo, no resgate do prazer do aprender. Metódo: Foram aplicados testes neuropsicopedagógicos, que propiciaram a obtenção de dados relevantes do aprendente quanto ao seu nível de desenvolvimento, identificação da maneira como se apropria do conhecimento e das interferências neste processo. Desenvolvimento/resultados: Após a aplicação dos testes constatamos que o aprendente experimenta interferências significativas nas áreas cognitiva, psicomotora, pedagógica e socioemocional requerendo acompanhamento pedagógico diferenciado e intervenção neuropsicopedagógica. Conclusão/considerações finais: Inferimos a relevância da avaliação e da intervenção neuropsicopedagógica no processo da reconstrução da autoestima, da convicção do sujeito em sua capacidade de superar as limitações que se interpõe na apreensão de conhecimento e do resgate do prazer do aprender.

The Brazilian Neonatal Resuscitation Program releases guidelines based on local interpretation of international consensus on science and treatment recommendations. We aimed to analyze whether guidelines for preterm newborns were applied to practice in the 20 Brazilian Network on Neonatal Research centers of this middle-income country. Prospectively collected data from 2014 to 2020 were analyzed for 8514 infants born at 230/7 to 316/7 weeks' gestation. The frequency of procedures was evaluated by gestational age (GA) category, including use of a thermal care bundle, positive pressure ventilation (PPV), PPV with a T-piece resuscitator, maximum fraction of inspired oxygen (Fio2) concentration during PPV, tracheal intubation, chest compressions and medications, and use of continuous positive airway pressure in the delivery room. Logistic regression, adjusted by center and year, was used to estimate the probability of receiving recommended treatment. For 3644 infants 23 to 27 weeks' GA and 4870 infants 28 to 31 weeks' GA, respectively, the probability of receiving care consistent with guidelines per year increased, including thermal care (odds ratio [OR], 1.52 [95% confidence interval (CI) 1.44-1.61] and 1.45 [1.38-1.52]) and PPV with a T-piece (OR, 1.45 [95% CI 1.37-1.55] and 1.41 [1.32-1.51]). The probability of receiving PPV with Fio2 1.00 decreased equally in both GA groups (OR, 0.89; 95% CI, 0.86-0.93). Between 2014 and 2020, the resuscitation guidelines for newborns <32 weeks' GA on thermal care, PPV with a T-piece resuscitator, and decreased use of Fio2 1.00 were translated into clinical practice.

Introduction: Social isolation has brought some negative consequences, including the increase in domestic violence, especially against the elderly, children, adolescents and women. Based on this principle, violence is now considered a global health problem, and the insertion of efficient public policies to collaborate with its reduction is essential, as well as inclusive actions that prioritize human rights and respect, being a primary task of power. public. Objective: To identify the consequences of violence during the period of social isolation. Methodology: This is an integrative literature review carried out from a survey in the scientific databases: LILACS, BDENF and SCIELO. Results and Discussions: Social isolation resulted in different negative points, especially regarding the aggravation of pre-existing comorbidities, mental disorders and domestic violence. What before, most of the time, family members spent in their jobs, in schools, in leisure tasks and outings, with the confinement measures reality has changed, causing a space of vulnerability for the occurrence of conflicts and family disagreements. At this point, violence increased significantly in this period and its effects are manifested in different circumstances, such as mental illness, suicide, deaths, social and economic damage and impacts on public health. With these results, there is a need for measures to combat domestic violence in all population groups. Conclusion: It was evidenced from this integrative review that social distancing caused numerous complications to the general population, especially with regard to public health problems. In this bias, violence was accentuated during the quarantine, under the various aspects mentioned in this study, causing trauma, aggression and irreversible occurrences to victims. &nbsp

Native human skin has been reported in the literature as being an important experimental model for studying skin biology. Studies performed by our group have shown that ex vivo skin, from elective plastic surgery, maintains the biological characteristics of native skin under specific culture conditions. As such, it might be a feasible model for the safety and efficacy testing of topical substances. While Brazil is at the forefront of global regulation implementation, Brazilian researchers are not always able to transfer certain widely used protocols to their laboratories, particularly protocols that involve the use of reconstructed tissues with limited viability, such as those for skin corrosion (OECD TG 431) and irritation testing (OECD TG 439). In this study, we investigated the applicability of the ex vivo skin model to the evaluation of irritation and corrosion potential of a number of proficiency substances described in TG 431 and TG 439. The skin fragments were standardised in size and diameter, and placed into cell culture inserts. The experimental protocol was conducted according to TG 431 and TG 439. The results obtained show that ex vivo skin could represent a promising tool for the evaluation of irritation and corrosion potential of substances (subject to inclusion and exclusion criteria), as recommended by OECD guidelines. While this is a proof-of-concept study, the use of ex vivo skin should be considered for such testing.

To evaluate the impact of an intervention improving the continuum of care monitoring (CCM) within HIV public healthcare services in São Paulo, Brazil, and implementing a clinical monitoring system. This system identified three patient groups prioritized for additional care engagement: (1) individuals diagnosed with HIV, but not receiving treatment (the treatment gap group); (2) individuals receiving treatment for >6 months with a detectable viral load (the virologic failure group); and (3) patients lost to follow-up (LTFU). The implementation strategies included three training sessions, covering system logistics, case discussions, and development of maintenance goals. These strategies were conducted within 30 HIV public healthcare services (May 2019 to April 2020). After each training session, professionals shared their experiences with CCM at regional meetings. Before and after the intervention, providers were invited to answer 23 items from the normalization process theory questionnaire (online) to understand contextual factors. The mean item scores were compared using the Mann-Whitney U test. The RE-AIM implementation science framework (evaluating reach, effectiveness, adoption, implementation, and maintenance) was used to evaluate the integration of the CCM. In the study, 47 (19.3%) of 243 patients with a treatment gap initiated treatment, 456 (49.1%) of 928 patients with virologic failure achieved suppression, and 700 of 1552 (45.1%) LTFU patients restarted treatment. Strategies for the search and reengagement of patients were developed and shared. Providers recognized the positive effects of CCM on their work and how it modified existing activities (3.7 vs. 4.4, p<0.0001, and 3.9 vs. 4.1, p<0.05); 27 (90%) centers developed plans to sustain routine CCM. Implementing CCM helped identify patients requiring more intensive attention. This intervention led to changes in providers' perceptions of CCM and care and management processes, which increased the number of patients engaged across the care continuum and improved outcomes.