Foundation for Science Technology and Civilisation

Over the last four decades, the escalation in diabetes and obesity rates has become epidemic all over the world. Diabesity describes the strong link between T2D and obesity. It correlates deeper with the elevated risks of developing cardiovascular disease hypertension, stroke, and several malignancies. Therapeutic usage of medicinal plants and natural products in the treatment of diabetes and obesity has long been known to physicians of Greco-Arab and Islamic medicine. Improved versions of their abundant medicinal plant-based formulations are at present some of the most popular herbal treatments used. Preclinical and clinical data about medicinal plants along with their bioactive constituents are now available, justifying the traditionally known therapeutic uses of products derived from them for the prevention and cure of obesity-related T2D and other health problems. The aim of this review is to systematize published scientific data dealing with the efficiency of active ingredients or extracts from Middle Eastern medicinal plants and diet in the management of diabesity and its complications. Google Scholar, MEDLINE, and PubMed were searched for publications describing the medicinal plants and diet used in the management of T2D, obesity, and their complications. The used keywords were “medicinal plants” or “herbals” in combination with “obesity,” “diabetes,” “diabetes,” or nephropathy. More than 130 medicinal plants were identified to target diabesity and its complications. The antidiabetic and anti-obesity effects and action mechanisms of these plants are discussed here. These include the regulation of appetite, thermogenesis, lipid absorption, and lipolysis; pancreatic lipase activity and adipogenesis; glucose absorption in the intestine, insulin secretion, glucose transporters, gluconeogenesis, and epigenetic mechanisms.

With the advances in neuroscience in the twenty-first century, there is an increased risk that this research could be used for non-peaceful purposes by state or non-state actors. The latter issue is generally referred to as the dual-use problem, which has created a heated debate among scientists and security experts about the duties and responsibilities of researchers where each side is reluctant to engage with the other in a cooperative manner. In order to break this stalemate, a project on how to improve ethics education for neuroscientists was carried out which led to the development of an open access, online 12-lecture module. This article discusses how the project followed an action research methodology. While theory proposes that action research can either deliver on a practical level or enable emancipation, the article will discuss how this research project managed to accomplish both. Furthermore, it draws on a critique of emancipation in the form of postmodern theory to discuss the emergence of power and its application.