Friedrich-Ebert-Krankenhaus

This study aims to improve student learning outcomes in Islamic religious education learning through the Project Based Learning Method. This study is a classroom action research that uses four steps, namely planning, action, observation and reflection. The subjects of this study were vocational high school students. The data for this study were obtained by test and observation techniques. Tests are used to measure learning and observations are used to analyze teacher and student learning activities. The data analysis technique used in this study is descriptive statistics by comparing the results obtained with indicators of research success. The results of the study indicate that through the Project Based Learning Method, it can improve student learning outcomes in Islamic religious education learning. This can be seen from the increase in the percentage of student learning completion in each cycle with details of the pre-cycle 40.89%, the first cycle 68.87% and in the second cycle it increased to 90.32%. Thus, through the Project Based Learning Method it can be used as an alternative to improve student learning outcomes in Islamic religious education learning.

DeliriumDelirium is common in hospitalised patients, and there is currently no specific treatment. Identifying and treating underlying somatic causes of delirium is the first priority once delirium is diagnosed. Several international guidelines provide clinicians with an evidence-based approach to screening, diagnosis and symptomatic treatment. However, current guidelines do not offer a structured approach to identification of underlying causes.A panel of 37 internationally recognised delirium experts from diverse medical backgrounds worked together in a modified Delphi approach via an online platform. Consensus was reached after five voting rounds. The final product of this project is a set of three delirium management algorithms (the Delirium Delphi Algorithms), one for ward patients, one for patients after cardiac surgery and one for patients in the intensive care unit.

Hypereosinophilic syndrome (HES) is defined as aperipheral eosinophil count of > 1500/μl (assessed twice at an interval of ≥ 2weeks) and an eosinophil-induced organ damage. Idiopathic HES is differentiated from primary (clonal or neoplastic) HES and secondary (reactive) HES, depending on the etiology. Eosinophilic granulomatosis with polyangiitis (EGPA) is categorized as asecondary form of HES and is characterized by hypereosinophilia and vasculitis of small to medium-sized vessels and can be associated with an antineutrophil cytoplasmic antibody (ANCA). The treatment of HES is dependent on the etiology. Clonal HES is treated according to the respective genetic aberration, e.g. with tyrosine kinase inhibitors or chemotherapy and allogenic stem cell transplantation. Secondary forms should be treated according to the underlying cause (e.g. parasitic infection). The treatment of EGPA is carried out with immunosuppressants depending on the disease stage and disease activity. Conventional drugs, such as glucocorticoids (GC), cyclophosphamide (CYC) and methotrexate (MTX) or biologics, such as the monoclonal anti-IL5 antibody mepolizumab are commonly used. Mepolizumab is also agood option for the treatment of idiopathic HES.

Giriş: Endovasküler tedavi yöntemlerinden biri olan chimney tekniğinin sonuçlarının yüz güldürücü olması, ucuz olması, fenestre stentlere ve hibrid yönteme göre avantajlarının bulunması bu yöntemin daha fazla tercih edilme sebebidir. Amaç: Kısa boyunlu jukstarenal aort anevrizmalarının greft stent ile endovasküler tedavisinde chimney tekniğinin sonuçlarının değerlendirilmesidir. Gereç-Yöntem: Çalışmaya 2008-2013 tarihleri arasında abdominal aort anevrizması nedeniyle girişimsel radyoloji bölümünde chimney tekniği uygulanarak endovasküler greft stent yöntemi ile tedavi edilen; preoperatif ve postoperatif bilgisayarlı tomografi anjiografi görüntüleri dijital radyoloji arşiv sisteminde kayıtlı olan jukstarenal aort anevrizmalı 17 hasta alındı. Hastaların preoperatif ve postoperatif dijital subtraksiyon anjiografi ve BTA görüntüleri retrospektif olarak değerlendirildi. Chimney tekniği kullanımının sonuçları tartışıldı. Bulgular: Çalışmaya alınan 17 hastanın yaş ortalaması 68.94±9.46’dır. Anevrizma etiyolojisinde 14 hastada ateroskleroz, 3 hastada ise vaskülit yer almaktaydı. 4 hastada operasyon öncesi anevrizma rüptürü mevcuttu. Hastaların anevrizma boyun uzunluğu ortalaması 3.02±2.8 mm (0-9 mm), operasyon sonrası takip süresi ortalaması 6.86±4.6 ay (1-16 ay) idi. Preoperatif ve postoperatif 6 ve 12. ay anevrizma çap ortalamaları arasında anlamlı fark bulundu (p<0.05). 17 hastaya planlanan toplam 28 chimney stent girişiminin 2’sinde chimney stentlerin yerleştirilmesi başarısızlıkla sonuçlandı (Başarı oranı %92.86). Başarılı olunan 15 hastanın 9’unda bilateral renal artere, 3’ünde sol renal artere, 2’sinde sağ renal artere, 1’inde SMA’ya chimney stent yerleştirildi. Takipte 3 hastada endoleak (2 hasta Tip IIA, 1 hasta Tip IA), 3 hastada toplam 4 arterde ise tromboz gelişti. Sonuç: Jusktarenal aort anevrizmalı bireylerin endovasküler tedavisinde chimney yönteminin kullanımı başarılı bir yöntemdir

The spread of viral diseases in eels is suggested to severely affect the European eel (Anguilla anguilla) panmictic population. The European Commission has initiated the Eel Recovery Plan (Council Regulation No. 1100/2007) to try to return the European eel stock to more sustainable levels within that measures eel restocking. However, scientific evidence evaluating the efficacy of stocking remains scarce. In addition, knowledge about the impact and contribution of eel stocking on the distribution of infectious diseases is insufficient. In this study, we aimed to investigate virus infections in batches of eels intended for restocking. We analysed samples of glass eels from certified fisheries and farmed European eels from different aquaculture farms. All analysed eels were purchased within a North Rhine Westphalian conservation program. Via a combination of cell culture and qPCR-based techniques, we detected infections of glass eels with the rhabdovirus Eel Virus European X and anguillid herpesvirus 1 infections in farmed eels (10-15 cm).