Frontier Scientific (United States)

ZONGOII hydropower station is a diversion-type power station constructed in Congo (Kinshasa), which uses Chinese funds and Chinese standards. However, during the implementation of the project, Gangfang Electric Power Company referred to the design form of the completed hydropower station and instructed me Fang added a first valve chamber at the end of the flat section of the pressure pipeline after the surge well, so that the technicians of the rigid side can use the familiar maintenance practices to perform maintenance and maintenance of the power plant units and butterfly valves. The purpose of this paper is to demonstrate the stability analysis of the additional valve room project based on the requirements of Chinese standards and the needs of rigid owners.

Abstract Larval mosquitoes are aquatic omnivorous scavengers which scrape food from submerged surfaces and collect suspended food particles with their mouth brushes. The composition of diets that have been used in insectaries varies widely though necessarily provides sufficient nutrition to allow colonies to be maintained. Issues such as cost, availability and experience influence which diet is selected. One component of larval diets, essential fatty acids, appears to be necessary for normal flight though deficiencies may not be evident in laboratory cages and are likely more important when mosquitoes are reared for release into the field in e.g. mark-release-recapture and genetic control activities.In this study, four diets were compared for rearingAnopheles gambiaeandAedes aegypti, all of which provide these essential fatty acids. Two diets were custom formulations specifically designed for mosquitoes (Damiens) and two were commercially available fish foods: Doctors Foster and Smith Koi Staple Diet and TetraMin Plus Flakes. Development rate, survival, dry weight and adult longevity of mosquitoes reared with these four diets were measured. The method of presentation of one diet, Koi pellets, was additionally fed in two forms, pellets or a slurry, to determine any effect of food presentation on survival and development rate.While various criteria might be selected to choose ‘the best’ food, the readily-available Koi pellets resulted in development rates and adult longevity equal to the other diets, high survival to the adult stage and, additionally, this is available at low cost.

Antimicrobial photodynamic inactivation (aPDI) employs the combination of nontoxic photosensitizing dyes and visible light to kill pathogenic microorganisms regardless of drug-resistance, and can be used to treat localized infections. A meso-substituted tetra-methylpyridinium porphyrin with one methyl group replaced by a C12 alkyl chain (FS111) and its Pd-derivative (FS111-Pd) were synthesized and tested as broad-spectrum antimicrobial photosensitizers when excited by blue light (5 or 10 J/cm2 ). Both compounds showed unprecedented activity, with the superior FS111-Pd giving 3 logs of killing at 1 nM, and eradication at 10 nM for Gram-positive methicillin-resistant Staphylococcus aureus. For the Gram-negative Escherichia coli, both compounds produced eradication at 100 nM, while against the fungal yeast Candida albicans, both compounds produced eradication at 500 nM. Both compounds could be categorized as generators of singlet oxygen (ΦΔ = 0.62 for FS111 and 0.71 for FS111-Pd). An in vivo study was carried out using a mouse model of localized infection in a partial thickness skin abrasion caused by bioluminescent Gram-negative uropathogenic E. coli. Both compounds were effective in reducing bioluminescent signal in a dose-dependent manner when excited by blue light (405 nm), but aPDI with FS111-Pd was somewhat superior both during light and in preventing recurrence during the 6 days following PDT.

Abstract Producers of pond-raised channel catfish Ictalurus punctatus in the southeastern United States can experience huge economic losses due to enteric septicemia of catfish (ESC) and columnaris disease and to the presence of certain odor-producing cyanobacteria in production ponds that result in “off-flavor” channel catfish. AquaFrin (lauryl methyl pyrifrin), a product currently being evaluated for commercial use, belongs to a class of porphyrins that have been shown to be very effective as antibacterial agents. As a preliminary step to assess the potential use of AquaFrin as a therapeutant against ESC and columnaris, we used a rapid bioassay to evaluate AquaFrin for antibacterial activity against the Gram-negative bacterium Edwardsiella ictaluri (etiological agent of ESC), two genotypes of the Gram-negative bacterium Flavobacterium columnare (etiological agent of columnaris disease), and the representative Gram-positive bacterium Staphylococcus aureus (American Type Culture Collection 29213) for comparison. In addition, we performed a bioassay-directed evaluation of AquaFrin for selective toxicity toward the musty cyanobacterium Planktothrix perornata. AquaFrin was found to possess antibacterial activity toward all tested bacteria and yielded the following minimal inhibitory concentration results: 0.5 mg/L for F. columnare isolate ALM-00-173, 1.0 mg/L for F. columnare isolate BioMed, 0.1 mg/L for S. aureus, and 9.8 mg/L for E. ictaluri. The range of 96-h 50% inhibition concentrations (0.07–0.2 mg/L) for AquaFrin toward P. perornata and the green alga Selenastrum capricornutum indicates strong potential for its use as a broad-spectrum algicide.