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In two studies of avoidance rate increases occurring in the presence of an unrein forced light CS that had been independently paired with shock, it was shown that the time elapsing between CS onset and the next avoidance response (latency) was a function of the amount of avoidance-safe time remaining. In the first study, it was found that a formula (safe time/3) would closely predict all of the mean latencies at RS = 20 sec. In a systematic replication with RS = 30 sec, the monotonie relationship was replicated, although the formula failed to predict the data. It was further shown that the time until the next avoidance response was shortened by the light onset, so that both operant and Pavlovian variables interact to control latencies in conditioned acceleration.

Amphetamine, Dexamyl and meprobamate were utilized in an effort to improve avoidance behavior in rats poor in avoidance performance. It was found that CAR acquisition among poor shuttle-box avoidance performers improved significantly with Dexamyl, but not with amphetamine and meprobamate.

Back to table of contents Previous article Next article ArticleNo AccessCOMMENTSOME DRUGS USED IN THE TREATMENT OF MENTAL DISORDERSH. E. HIMWICHH. E. HIMWICHSearch for more papers by this authorPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.115.8.756AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail PDFThis content is only available as a PDF. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited ByPhenothiazine BibliographiesPsychosomatics, Vol. 2, No. 4New England Journal of Medicine, Vol. 265, No. 12Journal of the American Pharmaceutical Association (Scientific ed.), Vol. 49, No. 7The Irish Journal of Medical Science, Vol. 35, No. 10The Lancet, Vol. 276, No. 7155The Lancet, Vol. 276, No. 7155British Journal of Pharmacology and Chemotherapy, Vol. 15, No. 1The Lancet, Vol. 274, No. 7108The Lancet, Vol. 274, No. 7108The Lancet, Vol. 274, No. 7108 Volume 115Issue 8 February 1959Pages 756-759 Metrics PDF download History Published online 1 April 2006 Published in print 1 February 1959