Gemini Eye Clinic

To demonstrate the surgical technique of the implantation of the trifocal IOL with the 7-mm large optic. The retrospective case series study included 94 eyes of 59 patients who underwent the routine laser-assisted cataract surgery through 5.0mm capsulotomy and were implanted with Triva-aXAY IOL (HumanOptics Holding AG, Erlangen, Germany) using the 3L implantation method. The 3L method consisted of three consecutive steps before and during the IOL implantation. The 3L implantation videos were analysed to determine the surgery course. The visual acuity and dysphotopsia occurrence were assessed at 6months postoperatively. The mean monocular CDVA, DCIVA and DCNVA were 0.0 ± 0.04 logMAR, 0.11 ± 0.12 logMAR and 0.07 ± 0.09 logMAR. Regarding dysphotopsia, 36% of patients reported no dysphotopsia at all. 'No or mild' halo, glare and starburst were reported in 79%, 64% and 64% of patients, respectively. The median time of IOL implantation (IQR) was 47.5 s (39; 68 s). The innovative 3L implantation technique enables the surgeons to implant the IOL with the large optic or bulky platform easily, safely and without additional manipulation. Video abstract in Supplement online material.

The application of polymeric biomaterial scaffolds utilizing crosslinking strategy has become an effective approach in these days. In the present study, the development and characterization of collagen–chitosan hydrogel film has been reported on using dual crosslinking agent’s, i.e., tannic acid and genipin simultaneously. Incorporation of genipin imparts a greenish-blue color to the polymeric film. The effect of dual crosslinking and their successful interaction within the matrix was evaluated by infrared analysis spectroscopy. The porosity of the film was examined using scanning electron microscopy (SEM). Results of TGA determine the intermediate thermal degradation. Further, the crosslinking phenomenon has found primary impact on the strength of the films. Enzymatic degradation for the films was performed with lysozyme and lipase. The cell adhesion and proliferation was also accomplished using mouse embryonic cell lines wherein the cells cultured on the dual crosslinked film. The thriving utilization of such dual crosslinked polymeric film finds their applications in ophthalmology especially as an implant for temporary injured cornea and skin tissue regeneration.