Gen Foundation

June O'Sullivan, chief executive of the London Early Years Foundation (LEYF), on the need to understand AI and its implications

ABSTRACT This paper describes how eight London nurseries examined whether better use of bicycles would strengthen children’s physical activity as a step to reducing child obesity. The nurseries are part of a social enterprise which offers one-third of the 4200 nursery places to children from poor and disadvantaged families/communities where rates of child obesity are high and increasing. The research was instigated because the nurseries built a partnership with Bikeworks which provided free bikes and staff wanted to ensure they were using them effectively to benefit children. Parents were involved but also asked a specific question about interest in a bike lending scheme. The paper concluded that staff became more observant of how they could enhance their practice using bikes to support children’s physical and sociolinguistic development. It heightened the importance of observation of the children but also in identifying barriers such as poor cycling surface and state of bike repairs. Parents considered bikes to be a key part of their children’s nursery life especially extending physical skills but were divided evenly about the value of introducing a bike lending scheme.

IntroductionOxygen is an essential medicine for children and adults. The current systems for its delivery can be expensive and unreliable in settings where oxygen is most needed. FREO2 Foundation Australia has developed an integrated oxygen system, driven by a mains-powered oxygen concentrator, with the ability to switch automatically between low-pressure oxygen storage device and cylinder oxygen in power interruptions. The aim of this study is to assess the clinical impact and cost-effectiveness of expanding this system to 20 community and district hospitals and level IV facilities in Western Uganda.Methods and analysisThis will be a phased implementation with preintervention and postintervention comparison of outcomes. Standardised baseline data collection and needs assessment will be conducted, followed by implementation of the FREO2 Oxygen System in combination with pulse oximetry in 1–2 facilities per month over a 16-month period, with a total 23-month data collection period. The primary outcome will be the proportion of hypoxaemic children receiving oxygen pre and post oxygen system. Secondary outcomes will assess clinical, economic and technical aspects. Pre and post oxygen system primary and secondary outcomes will be compared using regression models and standard tests of significance. Useability will be quantitatively and qualitatively evaluated in terms of acceptability, feasibility and appropriateness, using standardised implementation outcome measure tools.Ethics and disseminationEthics approval was obtained from Mbarara University of Science and Technology (MUREC 1/7) and the University of Melbourne (2021-14489-13654-2). Outcomes will be presented to the involved facilities, and to representatives of the Ministry of Health, Uganda. Broader dissemination will include publication in peer-reviewed journals and academic conference presentations.Trial registration numberACTRN12621000241831.

Oxygen therapy is an essential medicine and core component of effective hospital systems. However, many hospitals in low- and middle-income countries lack reliable oxygen access-a deficiency highlighted and exacerbated by the coronavirus disease (COVID-19) pandemic. Oxygen access can be challenged by equipment that is low quality and poorly maintained, lack of clinical and technical training and protocols, and deficiencies in local infrastructure and policy environment. We share learnings from 2 decades of oxygen systems work with hospitals in Africa and the Asia-Pacific regions, highlighting practical actions that hospitals can take to immediately expand oxygen access. These include strategies to: (1) improve pulse oximetry and oxygen use, (2) support biomedical engineers to optimize existing oxygen supplies, and (3) expand on existing oxygen systems with robust equipment and smart design. We make all our resources freely available for use and local adaptation.

Dialogic reading, where the child is prompted to be the teller of the story, has been a success at LEYF, explains June O'Sullivan explains

SENCO Hilda Miller advises a pre-school on the steps it needs to take to ensure it can welcome a child who has medical needs relating to a kidney condition. A risk assessment and care plan need to be established.

The da Vinci European BioBank (daVEB) is a research infrastructure established in 2009 in the Scientific Campus of the University of Florence (Sesto Fiorentino, Italy) belonging to the non-profit foundation FiorGen, which promotes studies aimed at exploiting knowledge on human health. Since 2011, daVEB is ISO9001 certified for collection, storage and distribution of biological samples and the associated data for scientific research. The biobank is currently storing about 9.000 biospecimens (serum, plasma, white cells, tissue, DNA, cells and urine) collected according to specific informed consents by Research Units from healthy donors and patients affected by different diseases - cardiovascular diseases, melanoma, breast carcinoma, non-Hodgkin’s lymphoma, cancer in geriatric patients, Krabbe syndrome, rare skin diseases; the biomaterial is available for new research projects.

Dieser Artikel wirft einen Blick auf das Gedenken an den nationalistischen Anführer Stepan Bandera (1909– 1959) seit der ukrainischen Unabhängigkeit. Er untersucht Bandera gewidmete Denkmäler, Tafeln, Museen und Straßen sowie andere Formen des Gedenkens in der gesamten Ukraine. Zudem behandelt er die Kontroversen um das Gedenken und dessen Politisierung.