- Research Article
- 10.1016/j.ekir.2026.104693
WCN26-2246 A Scientific Approach to Management of Chronic Kidney Disease Through Indian Traditional Polyherbal Formulation
- Mar 25, 2026
- Kidney International Reports
- Sn Gupta + 6 more +6
Publications from 2021 to 2026
Showing 10 of 232 papers
WCN26-2246 A Scientific Approach to Management of Chronic Kidney Disease Through Indian Traditional Polyherbal Formulation
A Review Article on Samsarjana Karma
Equilibrium state of Dosha Dhatu Mala composes a healthy human body. Ayurveda focuses to keep individual in a healthy state by prevention and cure of the disease. Ayurveda emphasizes two types of treatment modalities Samshamna and Samshodhana Chikitsa. Chikitsa is best as it ends up the root cause of disease by expelling accumulated vitiated Doshas. Shodhana is the internal purification of the body is broadly divided into three steps Poorva Pradhana and Paschat Karma although all three are equally important. After Shodhana Agni and Bala of the individual gets disturbed. To restore Agni and rebuild strength Paschat Karma i.e., Samsarjana Karma is advocated. Samsarjana Karma is an ancient diet regime followed in a sequential order with time duration in accordance to Samsodhana for nourishment of body on cellular level and enhancing power of Agni. Samsarjana Karma includes Peya, Vilepi, Akruta Yusha, Kruta Yusha, Akruta Mamsarasa, Kruta Mamsarasa.
Read moreReviewing Perimenopausal Symptoms: Through the Lens of Ayurveda
A woman navigates through several changes in her reproductive life, starting with menarche leading up to menopause which marks the end of it. Perimenopause is a transitional time between the beginning of hormonal changes leading to menstrual irregularities along with other psycho-physiological manifestations and one year after a woman’s final period. It is a natural stage when a woman moves from her childbearing years to a non-reproductive phase, usually between the ages of 40 and 50. While classical Ayurvedic texts do not specifically refer to this stage as a separate disease, the age known as Adhirudha Avastha can be correlated to the perimenopausal period. According to Ayurveda, it is a Jara Avastha Janya change brought upon by Kala. Although it is a normal part of a woman's life, today’s fast-paced and demanding lifestyle can make this phase more difficult, often affecting daily comfort and well-being. That’s why it is important to support the body and mind during this time, helping women adjust more smoothly to the changes. Understanding the Ayurvedic perspective of perimenopausal changes can enable us to better help thousands of women, trudging through this deeply personal, difficult phase of life and utilize the plethora of drugs mentioned for Jara Avastha, Rasayana & Dhatu Paripakwata (associated with this phase).
Read moreA Case Study on Ayurvedic Management of Palmoplantar Psoriasis (Eka Kustha)
Introduction: Palmoplantar Psoriasis (PPP) is a chronic and distressing dermatological condition affecting the palms and soles, characterized by erythematous plaques, scaling, deep fissures, and intense itching. According to Ayurveda, such conditions fall under a single yet broad term Kustha, with Vipadika being its closest correlate, exhibiting similar signs and symptoms. Improper dietary habits like Viruddha Ahara, stress, and environmental triggers often aggravate the condition, both in modern and Ayurvedic perspectives. Aims and Objectives: To evaluate the effectiveness of Ayurvedic Shamana Chikitsa in the management of Palmoplantar Psoriasis (Vipadika). Materials and Methods: A 42-year-old female patient presented with intense itching, redness on the lateral aspect of the foot, deep cracks, fissures, and pain during walking. Ayurvedic diagnosis of Vipadika was made based on clinical presentation. The outcome was measured based on symptomatic relief in signs and symptoms and based on PASI [Psoriasis area severity Index Scoring]. Internal as well as external application medication was given. Dietary and lifestyle modifications, Duration of treatment: 2 months, followed by 15 days of post-treatment follow-up. Photographic documentation confirmed visible healing [with patient consent]. Results: Significant reduction in itching and erythema within the first month. Complete healing of fissures and cracks observed by the end of the second month. No relapse of symptoms during the follow-up period.
Read moreMacroscopic and Physio-Chemical Description of an Ayurvedic Formulation Shigruadi Anjana
Shigruadi Anjana is a Ayurvedic formulation containing Moringa oleifera (Shigru), Azadirachta indica (Nimba), Berberis aristata (Daruharidra), Madhu (honey), and Saindhava Lavana (rock salt) which are known for its ocular benefits. The present study was conducted to analyze its macroscopic features, physico-chemical parameters, and identification using TLC. The pH was 4.92, loss on drying 4.59%, and refractive index was 1.468. TLC results confirmed the presence of marker compounds from Shigru, Nimba, and Daruharidra. These results provide a quality benchmark for the formulation and reinforce its traditional usage.
Read moreApplied Clinical Relevance of External Ayurvedic Therapies: A Conceptual Review
Ayurvedic literature describes several external procedures that are used for both treatment and maintenance of health. Among them, Lepa, Upanaha, Udvartana, and Abhyanga are frequently employed in clinical practice with specific indications and methods of application. The present work is a classical textual review undertaken to examine the practical and therapeutic relevance of these four procedures. References were collected from major Ayurvedic compendia and analyzed with respect to their definitions, classifications, procedural steps, indications, contraindications, and clinical utility. The review shows that Lepa is mainly applied in localized inflammatory and skin conditions, Upanaha in painful and stiff musculoskeletal disorders, Udvartana in obesity and Kapha-dominant states, and Abhyanga in neuromuscular and degenerative conditions. Each therapy follows defined guidelines regarding preparation and application. These findings support their continued relevance as structured, non-invasive interventions within contemporary integrative healthcare settings..
Read moreAccess to Institutional Finance for MSMEs: A Descriptive Study of Commercial Banks in India
Purpose:The purpose ofthe study is toexamineaccess toinstitutionalfinancefor Micro, Small and Medium Enterprises (MSMEs) in India, with special emphasis on the role played by commercial banks in facilitating credit availability. Methodology:The study adopts a descriptive research design based on secondary datacollected from Reserve Bank of India reports, Ministry of MSME publications, World Bank reports, and relevant research literature. Data are analysed using tables,percentages, and graphical tools. Findings:The study finds that commercial banks have significantly increased institutionalcredit to MSMEs, supported by policy initiatives such as priority sector lending and credit guarantee schemes. However, MSMEs continue to face challenges such as collateral requirements, procedural complexities, and limited financial literacy. Limitations:The study is limited to secondary data and focuses only on commercial banks, excluding NBFCs and informal sources of finance. Implications:The findings provide useful insights for policymakers, bankers, and MSME stakeholders to strengthen institutional credit mechanisms, simplify lending procedures, and enhance financial inclusion in the MSME sector.
Read moreAnatomical variations of hip acetabulum and femoral head-neck junction may predispose to clinical consequences: a case-based discussion of complex morphological interactions.
Femoroacetabular impingement (FAI) morphology is defined by anatomical variants that may predispose to mechanical conflict between the bony structures of the acetabulum and proximal femur with underlying bony incongruence leading to damage of adjacent tissues. Repetitive abnormal contact in this region can contribute to the formation of herniation pits (HPs) in the anterosuperior femoral head-neck junction, which may exacerbate symptoms and complicate surgical management of FAI. This case report describes a 55-year-old male who underwent arthroscopic osteochondroplasty for mixed-type FAI morphology, combined with resection of a large HP and subsequent cavity filling using allogenic bone graft. Importantly, even though he did not have classic acetabular overcoverage, focal acetabular retroversion resulted in mechanical impingement when combined with anatomical variation of the femoral head-neck junction and patient's activity patterns. The postoperative course was uneventful, and graft incorporation was confirmed during the three-year follow-up. This case highlights the anatomical and surgical interplay between osseous morphology, soft-tissue integrity, and joint biomechanics in the setting of FAI. Importantly, the various FAI morphologies should be considered anatomical variants that, when combined with specific movement patterns or loading conditions, may predispose to impingement and subsequent clinical symptoms. Additionally, this case demonstrates that allogenic bone grafts used to fill the herniation pit cavity can successfully incorporate into the surrounding bone, even in the anterosuperior femoral neck - a region known for relatively limited vascular supply.
Read moreA sport inspired kabaddi game optimizer for accurate parameter estimation of solar photovoltaic models.
This paper proposes a Kabaddi Game Optimizer (KGO), a sport-inspired metaheuristic for accurate solar photovoltaic (PV) modelling. KGO models Kabaddi strategies (Dubki and Akraman), adaptive weights and weak-player replacement to balance exploration and exploitation. Its performance is first validated on the CEC 2017 benchmark set against seven well-known optimizers, where KGO consistently attains the best average rank. KGO is then coupled with the Newton–Raphson method to estimate parameters of single, double, and triple diode PV models and a PWP-201 PV module. Using RTC France cell and module data, KGO achieves RMSE values of 7.729857E−04, 7.43146E−04, 7.3771E−04, and 2.0529E−03 for the single-, double-, and triple-diode models, and the PV module, respectively, demonstrating accurate, robust, and fast PV parameter estimation.
Read moreAyurvedic Management of Amenorrhea Associated with Hypoplastic Uterus
Amenorrhea associated with hypoplastic uterus presents a therapeutic challenge, as conventional hormonal therapies often show limited effectiveness. Ayurveda provides a holistic approach aimed at correcting Dosa imbalance, nourishing reproductive tissues, and restoring Artava Pravṛtti (menstrual function). Integrating Panchakarma procedures with targeted oral medications may enhance therapeutic outcomes. Objective: To evaluate the efficacy of a combined Ayurvedic protocol- including sequential Panchakarma therapy and oral formulations such as Ashwagandha Ksheerapaka, Shatapushpa Churna and Abhipattikar Churna- in the management of amenorrhea associated with hypoplastic uterus. Methods: A 20year-old nulligravid female with amenorrhea and ultrasonographically confirmed hypoplastic uterus underwent Vamana Karma, followed by Niruha Vasti with Dashamula Kwatha for three days, Uttaravasti with Phala Ghṛita for five days, and Matra Vasti with Balashvagandha Taila. Concurrently, she received oral medications throughout the treatment. The protocol was repeated for three consecutive cycles. Outcomes were assessed through menstrual pattern, uterine dimensions, endometrial thickness, and subjective wellbeing. Results: Progressive improvement was observed in uterine size, endometrial development, and menstrual regularity, with normal menstruation restored by the third cycle, without adverse effects. Conclusion: Sequential Panchakarma therapy combined with specific Ayurvedic oral medications shows promising effectiveness in restoring menstruation and enhancing uterine development in hypoplastic uterus.
Read more