- Research Article
- 10.1016/j.bioadv.2026.214842
PLZ4@SeD-induced ferroptosis sensitizes bladder cancer to chemotherapy and immunotherapy.
- Aug 01, 2026
- Biomaterials advances
- Xuanfan Liu + 8 more +8
Publications from 2021 to 2026
Showing 10 of 2,640 papers
PLZ4@SeD-induced ferroptosis sensitizes bladder cancer to chemotherapy and immunotherapy.
Accurate monitoring of female reproductive hormones using a dual-enhanced ultrasensitive immunosensor.
Dendritic cell vaccines: Current research progress, challenges, and opportunities
This review examines the advancements in cancer immunotherapies, particularly focusing on dendritic cell (DC)-based vaccines developed through in vitro methods. DCs are essential for connecting innate and adaptive immunity and serve as powerful antigen-presenting cells. They play an essential role in the anti-tumor immune response by activating cytotoxic T lymphocytes and natural killer cells. DC vaccines, which involve engineering DCs to express tumor-associated antigens and administering them to patients, potentially enhance the T-cell-mediated destruction of tumor cells. The review details the progression of DC vaccine preparation from simple antigenic peptide pulsing to advanced genetic modification and cell fusion techniques. It discusses the use of envelope fusogenic membrane glycoproteins and chemical agents, such as polyethylene glycol, to facilitate the fusion of DCs with tumor cells, creating fusion cell vaccines that exhibit anti-tumor efficacy in both preclinical and clinical settings. Recent developments of DC vaccines have utilized alternative vectors, addressing some limitations of previous vaccine generations. Additionally, the review examines the integration of DC vaccines with other immunotherapies to combat tumor-induced immunosuppression. Despite their potential, DC vaccines face challenges that necessitate further refinement of therapeutic strategies and clinical validation. In conclusion, this review underscores the pivotal role of DC vaccines in cancer therapy and elucidates ongoing endeavors to augment their efficacy via combination therapies and advanced preparation techniques.
Read moreDesign, synthesis, and in vitro/in vivo biological evaluation of Artesunate-Ebselen derivatives: GPX4-targeted ferroptosis induction and synergistic antitumor immune activation in colorectal cancer.
Efficacy of Rhizoma Drynariae (Drynaria roosii Nakaike) extracts in treating osteoporosis in rat models: A systematic review and meta-analysis.
Maxillary bone and dento-alveolar changes in cleft lip and palate patients: Total maxillary distraction osteogenesis versus anterior maxillary segmental distraction osteogenesis.
Harnessing synergy: Innovative combinations to overcome PARP inhibitor resistance in cancer treatment.
Association of dietary intake of copper and zinc with systemic inflammation: A cross-sectional study integrating machine learning.
Collateral Circulation Outweighs Therapeutic Modality in Predicting Outcomes of Symptomatic MCA Stenosis: A Triple-Center Retrospective Cohort.
Apolipoprotein J-mediated hepato-renal crosstalk drives renal injury in chronic kidney disease.