Hospital Napoleão Laureano

Clear cell papillary renal cell tumor is a common and sometimes underdiagnosed renal cell neoplasm. Its proper recognition is important because its diagnosis implies a remarkably high probability of indolent behavior. This study aimed to evaluate the frequency of a fibrous capsule, a cystic component, and a GATA3 expression in clear cell papillary renal cell tumors. We assessed 419 renal cell neoplasms from three institutions located in northeastern Brazil and identified 42 clear cell papillary renal cell tumors (from 39 patients), which were the fourth most common renal cell neoplasm. These tumors commonly exhibited fibrous capsules (all showed complete or partial capsules) and cystic component (93%). Eighteen out of 42 tumors (43%) showed some expression of GATA3, and weak and focal staining was common among the positive tumors. Clear cell papillary renal cell tumor must always be included in the differential diagnosis of predominantly cystic renal cell neoplasms. As GATA3 is inconsistently expressed in clear cell papillary renal cell tumors, it is not useful in this diagnosis.

Objetivo: Investigar a influência da disfagia na qualidade de vida de pacientes com câncer em cuidados paliativos. Métodos: Realizou-se um estudo de campo, exploratório descritivo, com abordagem quantitativa. Para analise dos dados foram utilizados os testes Qui-quadrado, o software estatístico R (v2.11.0) e considerada significância menor a 5%. Resultados: Foram incluídos 35 pacientes, com prevalência do gênero feminino (77%), idade média de 45 anos e diagnóstico de câncer de mama (37%) e de pulmão (14%). Nesse estudo observou que sintomas relacionados às alterações na deglutição estiveram presentes: na consistência líquida e sólida, a tosse (20,0% e 8,6% respectivamente), na pastosa estase em cavidade oral (8,6%) e tempo prolongado de alimentação (8,6%). As alterações na deglutição influenciaram na qualidade de vida dos pacientes (37%), com associação do escape de alimento, estase, ruído e tosse. Conclusão: A ocorrência da disfagia declina a qualidade de vida de pacientes com câncer em cuidados paliativos.

Objetivo: Determinar o perfil dos subtipos moleculares dos carcinomas invasivos de mama entre mulheres que realizaram o estudo imuno-histoqumico de maio 2013 a dezembro de 2014, no Hospital Napoleo Laureano, Paraba, alm de caracterizar a idade mdia ao diagnstico e descrever os percentuais das seguintes variveis: receptor de estrognio e de progesterona, fator de crescimento epidrmico humano do tipo 2 e ndice mittico (Ki-67). Mtodo: Estudo retrospectivo, ecolgico, a partir da base de dados secundrios do Laboratrio de Anatomia Patolgica do Hospital Napoleo Laureano. A populao foi composta de 683 casos de carcinoma invasivo da mama, com estudo imuno-histoqumico realizado nessa instituio entre

Background: In 2016, Hodgkin’s Lymphoma (HL) was responsible for 2,470 new cases in Brazil and, despite recent scientific advances, there are unmet medical needs that affects patients’ outcome. Therefore, we aimed to explore the unmet medical needs in the management of HL patients in Brazil, based on experts’ perspective. Methods: A questionnaire was developed to address the unmet medical needs including barriers for the diagnosis and treatment of HL in Brazil. The questionnaire results were presented in a panel discussion to validate participants’ responses and to collect additional data. Main results: Eight experts participated in the panel. On both healthcare systems, public and private, a slight majority of patients was women and most of them were under 60 yearsold. In addition, the majority of patients were referred from another specialty on both systems. The time from onco-hematologist appointment to diagnosis was different between public and private sector (median of 30 and 12.5 days, respectively). Most patients in the public sector were on stage III (33%) and IV (33%); in the private sector, most patients were on stages II (36%) and III (24%). The most common barriers were the delayed diagnosis and the unavailability of diagnostic procedures and treatment options. Conclusion: According to participants, issues related to infrastructure and healthcare resource allocation affects the management of HL. Improvements in the infrastructure and educational measures for physicians and patients may contribute to minimize the barriers.

Os autores apresentam imagens de dermatoscopia em uma fruta (manga-rosa), contaminada pela antracnose, mostrando sua semelhança com o melanoma extensivo superficial.