Intech (Slovakia)

The system to be presented has been conceived with the intention of storing large amount of cement in horizontal warehouses. This new storage system allows the use of existing warehouses and enclosures on ports and cement plants, avoiding the expensive construction of either vertical concrete, steel silos or domes, and the use of front loaders to reclaim the product.

Abstract Objective: Objective: Resveratrol (RSV) is a multi-target drug that has demonstrated activity against Toxoplasma gondii in macrophage and HFF cell line infection models. However, its mechanism of action has not been determined yet. With the aim of determining a possible mechanism of anti-T. gondii action, we analyzed the effect of RSV on histones H3 and H4 lysine 16 acetylation (H4K16). RSV-induced DNA damage of intracellular tachyzoites was assessed as well by using the DNA damage marker phosphorylated histone H2A.X (gH2AX).Results: RSV inhibited intracellular T. gondii tachyzoite growth at concentrations below the toxic effect on host cells. The IC50 value in a 24-hours treatment was 53 mM. RSV induced a reduction in H4K16 acetylation (H4K16ac), a mark associated to transcription, DNA replication and homologous recombination repair. The same deacetylating effect was observed on histone H3. RSV also enhanced the SQE motif phosphorylation on T. gondii H2A.X (termed γH2A.X), a DNA damage associated PTM. Our findings suggest a possible link between RSV and DNA damage or DNA repair process maybe associated to DNA replication stress.

A number of experimental investigations on fibre reinforced polymer (FRP), with the aim of understanding their behaviour when applied as strengthening of reinforced concrete elements, are available in the literature but very few information is available on strengthening real-scale elements with cementitious composites. In particular design code formulations are scanty or non-existent.In this study the behaviour of four precast pre-stressed TT beams taken from an existing industrial building was investigated. One of them was considered as control unstrengthened TT beam, whereas the others were strengthened with different techniques, namely with FRP laminates (glued with epoxy resin), carbon fibres with cementitious matrix and steel fibres with cementitious matrix. Each material involved in this study was also mechanically characterized to obtain the main physical properties. Adequate specimens were obtained from the existing TT beam to characterize the concrete and the reinforcing steel bars.

Nowadays, it is necessary to develop new building materials, which are in accordance to the principles of the following provisions of the Roads Act: The design of road is a subject that follows national technical standards, technical regulations and objectively established results of research and development for road infrastructure. Foam concrete, as a type of lightweight concrete, offers advantages such as low bulk density, thermal insulation and disadvantages that will be reduced by future development. The contribution focuses on identifying the major material characteristics of foam concrete named Poroflow 17-5, in order to replace cement-bound granular mixtures. The experimental measurements performed on test specimens were the subject of diploma thesis in 2015 and continuously of the dissertation thesis and grant research project. At the beginning of the contribution, an overview of the current use of foam concrete abroad is elaborated. Moreover, it aims to determine the flexural strength of test specimens Poroflow 17-5 in combination with various basis weights of the underlying geotextile. Another part of the article is devoted to back-calculation of indicative design modulus of Poroflow based layers based on the results of static plate load tests provided at in situ experimental stand of Faculty of Civil Engineering, University of Žilina (FCE Uniza). Testing stand has been created in order to solve problems related to research of road and railway structures. Concern to building construction presents a physical homomorphic model that is identical with the corresponding theory in all structural features. Based on the achieved material characteristics, the tensile strength in bending of previously used road construction materials was compared with innovative alternative of foam concrete and the suitability for the base layers of pavement roads was determined.

Hedge funds sometimes use mathematical techniques to capture the short-term volatility of stocks and perhaps other types of securities. This sort of strategy resembles market making and is sometimes considered a form of statistical arbitrage. This study shows that for the universe of large-capitalization U.S. stocks, even quite naive techniques can achieve remarkably high information ratios. The methods used are quite general and should be applicable also to other asset classes.

<div class="htmlview paragraph">This paper investigates the accuracy of vehicle pre-braking speed estimates based upon tire/roadway coefficient of friction (drag factor) measurements and skid mark measurements. Data was collected to determine if there were any correlations between pre-braking speeds and pre-skidding speeds. Braking tests were performed on three vehicles using various measurement devices including an accelerometer, a fifth wheel, a radar gun, and a shot marker (bumper gun) system. The vehicle speeds, braking distances, skid mark distances, and deceleration histories were recorded. From this data, coefficients of friction for the tested road surface were evaluated. The coefficients of friction were then used in combination with the measured skid mark distances to calculate the vehicle pre-skidding speeds. The calculated pre-skidding speeds were then compared to the actual pre-braking speeds of the vehicles in order to establish the accuracy of the calculation methodology. A correlation between the calculated pre-skidding speed and the actual pre-braking speed was established for the study data.</div>