- Research Article
9
- 10.1111/eve.13845
Advances in the understanding, detection and management of equine strangles
- Jun 28, 2023
- Equine Veterinary Education
- Luke A Mclinden + 5 more +5
SummaryStreptococcus equisubspeciesequi(S. equi) is the causative organism of the upper respiratory disease of equids, strangles, characterised by pyrexia, lymphadenopathy and mucopurulent nasal discharge. Strangles was first reported over 750 years ago and continues to be of significance in equine populations across the globe. This review discusses howS. equihas adapted, the clinical manifestation of strangles, and how clinicians and caregivers can tackle the disease in the future.S. equievolved from the commensal, and occasionally opportunistic pathogen,Streptococcus equisubspecieszooepidemicusrefining its capabilities as it became host restricted. The success ofS. equican be attributed to its ability to cause both acute and persistent infection, the latter occurring in about 10% of those infected. In this carrier state,S. equipersists in the guttural pouch without causing clinical signs, intermittently shedding into the environment, and encountering naïve animals. Insight into theS. equigenome and lifestyle has led to advances in diagnostic assays and the development of a safe and efficacious recombinant‐fusion vaccine, giving clinicians and caregivers the tools to better combat this infection. Alongside rigorous biosecurity protocols and pragmatic control measures such as screening new arrivals for exposure and carrier status, these new technologies demonstrate that strangles can be an increasingly preventable infection.
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