Istanbul Aydın University

Purpose: This study aims to examine the relationship between Internet of Things (IoT) awareness and resistance to organizational change in businesses, and to investigate the potential mediating role of artificial intelligence (AI) anxiety in this relationship.Method: The research was conducted using a quantitative research design. Data were collected through a survey administered to 427 participants working in the energy sector between November 15, 2024, and December 5, 2024, using a convenience sampling method. The collected data were analyzed using SPSS and AMOS statistical software, and structural equation modeling was employed.Findings: The results indicate that IoT awareness has a negative and significant effect on AI anxiety (β = -0.23; t = -4.19; p < 0.05). AI anxiety was found to have a positive and significant effect on resistance to organizational change (β = 0.38; t = 6.80; p < 0.05). Additionally, IoT awareness has a negative and significant effect on resistance to organizational change (β = -0.44; t = -7.94; p < 0.05). Mediation analysis revealed that AI anxiety plays a significant mediating role in the relationship between IoT awareness and resistance to organizational change (IE = -0.08; SBT = -3.33; p < 0.05). The findings demonstrate that increasing IoT awareness reduces resistance to organizational change while also contributing to a decrease in AI anxiety.Original Contribution: This study contributes to the literature by examining the relationships among IoT awareness, AI anxiety, and resistance to organizational change within an integrated conceptual framework. By revealing the mediating role of AI anxiety, the study highlights the importance of human and psychological factors in the adoption of IoT technologies and digital transformation processes within organizations.

Aims: Endoscopic submucosal dissection (ESD) is an established technique for the curative resection of large colorectal lesions; however, intraoperative bleeding remains a major technical challenge. Electrosurgical coagulation modes are modifiable procedural factors that may influence bleeding control and procedural efficiency. This study aimed to compare the clinical outcomes of Swift and Spray coagulation modes during colorectal ESD. Methods: This retrospective, single-center study included 594 consecutive patients who underwent colorectal ESD between January 2021 and December 2025. Patients were divided into the Spray and Swift coagulation groups according to the coagulation mode used during submucosal dissection. Procedural characteristics, intraoperative and delayed bleeding, perforation rates, and other adverse events were analyzed and compared between groups. Results: Baseline patient and lesion characteristics were comparable between the two groups. The mean procedure time was significantly shorter in the Spray coagulation group compared with the Swift coagulation group (42.2±23.7 vs 51.7±31.9 minutes, p

Bu araştırmanın temel amacı, konu bağlamının okul öncesi öğretmenlerinin fen eğitimine yönelik pedagojik alan bilgilerini nasıl etkilediğini belirlemektir. Ayrıca, öğretmenlerin mesleki ve öğretim deneyimlerinin, fen eğitimine yönelik pedagojik alan bilgileri üzerindeki olası etkileri incelenmiştir. Araştırma kapsamında, altı hafta süren bir eğitim süreci planlanmış ve farklı deneyim seviyelerine sahip dört okul öncesi öğretmeni ikili gruplara ayrılmıştır. Birinci grup, derslerini bilimsel konular (maddenin halleri, çözünürlük vb.) bağlamında yürütmüştür. Diğer grup ise derslerini sosyobilimsel konular (küresel ısınma, beslenme vb.) bağlamında işlemiştir. Araştırma verileri, altı haftalık süreç öncesinde ve sonrasında ders planları ile yarı yapılandırılmış görüşme soruları aracılığıyla toplanmıştır. Bu veriler, pedagojik alan bilgisi (PAB) bileşenlerine göre alt kategorilere ayrılarak PAB analizi, numaralandırma yöntemi ve PAB haritalama tekniğiyle değerlendirilmiştir. Sonuçlar, okul öncesi öğretmenlerinin temel anlamda sosyobilimsel konularda fen eğitimine daha yatkın olabileceklerini göstermiştir. Diğer yandan katılımcıların çocukların kavrayışlarını ve öğretim stratejilerini öncelikli gördükleri, ancak fen eğitimini müfredat bileşenleriyle ilişkilendirme konusunda yetersiz kaldıkları tespit edilmiştir.

This study aimed to evaluate the perspectives of special education professionals regarding movement education programs. The research was conducted with 15 professionals working in special education and rehabilitation centers in Istanbul, including special education teachers, child development specialists, psychologists, and physical therapists. Data were collected through semi-structured interviews developed with expert feedback to ensure content validity. The findings indicate a strong consensus among professionals on the positive contributions of movement education to the development of individuals with special needs. Participants emphasized that movement education supports psychomotor and coordination skills, self-regulation, social adaptation and communication, as well as cognitive functions such as attention, focus, and dual-task performance. In addition, movement education was reported to indirectly enhance classroom harmony and academic performance by reducing aggressive and stereotypical behaviors and increasing self-confidence. Despite these benefits, the results reveal that movement education has not been sufficiently integrated into Individualized Education Programs due to limitations in physical space and a lack of specialized expertise. Participants also reported insufficient professional knowledge and highlighted the need to increase family awareness regarding the importance of movement education. Overall, the findings demonstrate that movement education plays a multidimensional and critical role in the development of individuals with special needs and should be integrated into special education programs in a planned, mandatory, and interdisciplinary manner to ensure sustainable and effective implementation.

Inherited kidney diseases represent a genetically and clinically heterogeneous group of disorders affecting both pediatric and adult populations. Advances in next-generation sequencing (NGS) have improved diagnostic precision; however, genotype-phenotype correlations and diagnostic yield vary substantially across disease entities. We retrospectively evaluated 165 patients referred for genetic testing due to suspected inherited kidney disease. Patients were classified into three clinical groups: polycystic kidney disease, Alport syndrome, and other syndromic patients with inherited kidney diseases. Genetic analysis was performed using NGS with Human Phenotype Ontology-based gene filtering and included evaluation of both single-nucleotide variants and copy number variations. Overall diagnostic yield differed markedly between groups. A molecular diagnosis was achieved in 71.4% of Alport patients, 41.0% of PKD patients, and 70.2% of patients in the Other syndromic group. In the Alport group, variants were identified exclusively in COL4A3, COL4A4, and COL4A5, with pathogenicity and gene involvement correlating with disease severity and the presence of extrarenal manifestations. The PKD group showed predominant involvement of PKD1, followed by PKHD1 and PKD2, while a substantial proportion of patients remained genetically negative, reflecting technical and biological complexity. The Other group exhibited pronounced genetic heterogeneity, with variants distributed across multiple genes involved in tubular, glomerular, metabolic, and ciliopathy-related pathways. Computational assessments demonstrated that several variants of uncertain significance (VUS) were located in functionally critical domains and were predicted to disrupt protein stability, intermolecular interactions, or conserved structural motifs, thereby supporting the biological plausibility of their potential pathogenic impact. Phenotype-driven NGS enables effective molecular diagnosis across diverse inherited kidney diseases while revealing disease-specific differences in diagnostic yield and genotype-phenotype correlations. Systematic inclusion of variants of uncertain significance and careful integration of genetic and clinical data are essential for accurate interpretation and long-term patient management. Collectively, this study enhances understanding of inherited kidney diseases and underscores the value of integrating comprehensive genomic and computational approaches into routine nephrogenetic practice.

Bu çalışmanın amacı, Bilgi ve İletişim Teknolojileri (BİT) sektöründe faaliyet gösteren işletmelerde farklı Liderlik Tarzlarının (LT), Yeşil İş Etiği (YİE) üzerindeki etkilerini incelemektir. Araştırma kapsamında İstanbul’da faaliyet gösteren Türkiye’nin önde gelen üç bilgi ve iletişim teknolojileri (BİT) sektörü operatörünün (Vodafone, Turkcell, Türk Telekom) ofis ve çağrı merkezi çalışanlarından oluşan 400 kişilik örnekleme çevrimiçi anket uygulanmıştır. Elde edilen veriler korelasyon, regresyon ve düzenleyici değişken analizleri ile değerlendirilmiş, analizler IBM SPSS 30.0 ve SPSS Process Macro kullanılarak gerçekleştirilmiştir. Analiz sonuçları, farklı LT’larının YİE üzerinde anlamlı etkileri olduğunu göstermiştir. Katılımcı, destekleyici ve yönlendirici liderlik tarzlarının çalışanların çevresel duyarlılık ve İş Etiği davranışlarını olumlu yönde etkilediği belirlenmiştir. Ayrıca, yönlendirici LT’ının da YİE üzerinde önemli etkisi olduğu tespit edilmiştir. Bulgular, liderlik biçimlerinin yalnızca çalışan motivasyonu ve performansını artırmakla kalmayıp, çevresel etik ve sürdürülebilirlik bilincini de şekillendirdiğini ortaya koymaktadır. Çalışmanın sonuçları, BİT sektöründeki yöneticilere ve insan kaynakları politika belirleyicilere çevresel sürdürülebilirliği teşvik eden liderlik yaklaşımlarını benimsemenin, çalışanların YİE davranışlarını artırmada etkili olduğunu göstermektedir. Sonuçlar, literatüre BİT sektöründe LT’ları ve YİE ilişkisinin ampirik verilerle desteklenmiş özgün bir katkısını sunmakla beraber, sürdürülebilir iş uygulamalarının geliştirilmesine yönelik politika ve stratejilerin oluşturulmasında yol gösterici niteliktedir.