John Tiller Software (United States)

Listeriosis and toxoplasmosis are foodborne illnesses that can have long-term consequences when contracted during pregnancy. Listeriosis is implicated in stillbirth, preterm labor, newborn sepsis, and meningitis, among other complications. Toxoplasmosis is associated with blindness, cognitive delays, seizures, and hearing loss, among other significant disabilities. Healthcare providers who understand the fundamentals of Listeria and Toxoplasma infection will have the tools to identify symptoms and high-risk behaviors, educate women to make safer decisions, and provide anticipatory guidance if a pregnant woman would become infected with either of these foodborne illnesses.

In this article we try to register the actions for food demands occurred in 1989 and 1990 within an analitical framework that seeks to explain the changes in popular classes's mobilization related to system's transformations as a whole, reflexing about the double meaning of what happened: as a continuity of a particular politicity that tried to express itself in the public space, but also, as a break in the senses and repertoires of collective action. We consider these actions -where looting appears as a form of collective violence-not only as a reaction to terminal crisis's situation of Ral Alfonsn's government but, also, as a "contentious" politics that intended to express demands through different channels of routine policy, validated in general elections of May 14th 1989.

GPSS/PC is a popular implementation of the discrete event simulation language GPSS, the General Purpose Simulation System. GPSS/PC has interactive graphics and animation tightly integrated into its simulation environment. Its graphics windows allow viewing and manipulation of the simulation via an optional pointing device, and assertion of all simulation primitives. All windows are online, providing for a visualization of model dynamics, and one of the windows allows animations of the simulation to be played out in an essentially unbounded virtual screen. A CAD based animation postprocessor is now available which can create a detailed 3D animation based on a previously recorded GPSS/PC animation. Using the postprocessor, the animation space can be placed in 3D, and an arbitrary amount of detail can be added to the objects and layout of the animation. A variety of rendering and speedup options are then available. This tutorial presents the interactive graphics, built-in animation, and CAD based postprocessor animation available with GPSS/PC.

Military missions often require drivers to maneuver across hazardous, off-road terrain using visual displays rather than direct vision. When soldiers use 2D displays, significantly more mobility errors occur than when soldiers use 3D displays that provide a stereoscopic view of the terrain. The purposes of the present experiment were to quantify the visual forewarning of a drop-off provided by a stereoscopic 3D display compared to a 2D display, and to measure the potential of increased camera separation (i.e., hyperstereo) for enhancing the benefit of 3D for the detection of terrain drop-offs. This experiment consisted of four viewing conditions: 0X (the 2D condition), 1X (stereo with the normal interpupillary distance [IPD] between the viewpoints provided to the two eyes), 2X (stereo with twice the normal IPD), and 3X (stereo with three times the normal IPD). Thirty-two participants viewed 80 video clips, each clip depicting an approach to a terrain drop-off as would be seen in a daytime driving situation. As soon as the drop-off became apparent, he or she pressed a brake pedal. As expected, the average detection time for drop-offs viewed with 1X (stereo display) was significantly better than when drop-offs were viewed with the 0X (2D) display. The failure to observe further improvements in task performance with 2X and 3X IPD suggests follow-on research to determine whether these unexpected hyperstereo results may be attributable to adverse side effects of hyperstereo: increased mismatch between accommodation and convergence, the minification effect, and increased stereoscopic “frame violation.”

The 30-day mortality as well as morbidity for stroke and myocardial infarction were determined by review of the charts for every carotid endarterectomy (N = 389 operations on 356 patients) performed at Wake Forest University Medical Center from 1979 through 1983 to ascertain whether the 16% morbidity and 6% mortality documented in our previous report of 1978 had changed over time. For endarterectomies performed on asymptomatic patients (n = 155), major morbidity included 2 myocardial infarctions and 1 stroke (1.9%). There were 3 fatalities--2 myocardial infarctions and 1 stroke (1.9%). For the symptomatic group (n = 234), major morbidity was 2.1%, mortality 2.6%. The combined morbidity for asymptomatic and symptomatic carotid stenosis was 2%, mortality 2.3%. Perioperative stroke rate (morbidity plus mortality) was 2.6%, 9 ipsilateral to the carotid endarterectomy, suggesting distal embolism as its probable cause. We contend that quality control measures implemented to correct the unacceptable rates reported in 1978 have contributed to dramatic and sustained reductions in complication rates.

To test for possible differences in local conformation and S1 flexibility, bovine cardiac and rabbit skeletal myosins were labeled with a fluorophore (1,5-IAEDANS) and a spin label having iodoacetamide reactivity. The marked activation of the Ca2+-ATPase (6- to 8-fold) and inhibition of the K+ (EDTA)-ATPase (80-90%) by both labels indicated specific labeling of the fast-reacting thiols (SH1) of both myosins. Fluorescence depolarization studies of 1,5-IAEDANS-labeled cardiac myosin indicated that, like skeletal myosin, the SI moieties of cardiac myosin exhibit considerable segmental flexibility with respect to the rod portion of the molecule. This indicates that segmental flexibility may be a property of all myosins. Cardiac and skeletal myosins immobilized spin labels to approximately the same extent, indicating a similarity in steric restraints around the SH1 thiol of the two myosins. The magnitude of the changes in spin label mobility accompanying binding of MgADP and hydrolysis of MgATP was reduced in cardiac myosin relative to skeletal myosin. This suggests that the lower catalytic center activity of cardiac myosin is associated with more restricted conformational changes accompanying formation of M.ADP and M.ADP.Pi. From measurements of spin label mobility, the affinity of cardiac and skeletal myosin for ADP were similar: Kd (ADP) = 7 microM, n = 1.6. The EPR spectrum of spin labels attached to cardiac and skeletal myosin showed similar saturation effects upon actin binding indicating immobilization of myosin heads occurs with both proteins.