Kanazawa Institute of Technology

Ultrasonic fatigue testing provides an accelerated method for evaluating very-high-cycle fatigue (VHCF); however, its high test frequency induces self-heating in carbon fiber-reinforced plastic (CFRP) composites. To investigate the effect of self-heating, we conducted hydraulic fatigue tests at multiple temperatures and ultrasonic fatigue tests on quasi-isotropic CFRP laminates. In the S-N diagram, the fitting curves of the hydraulic fatigue test at each temperature intersected at approximately 109 cycles, suggesting that self-heating below 80°C has only a minor influence on final failure in the VHCF regime. However, the quantitative evaluation of cracks per layer revealed different accumulation behaviors, indicating the influence of thermal residual stress and temperature-dependent properties of the epoxy. These results show that although ultrasonic testing is effective for evaluating the fatigue life in VHCF, interpreting the damage mechanisms requires careful consideration of the thermal effects caused by self-heating.

The transition to sustainable thermosetting resins is frequently hindered by the trade-off between high bio-based content and processability. This study reports a novel strategy in developing a highly bio-based, styrene-free unsaturated polyester resin (UPR) by leveraging maltodextrin-derived mixed esters dissolved in dimethyl itaconate (DMI). Unlike conventional polysaccharide-based systems that suffer from extreme viscosity, our functionalized prepolymer-DMI system achieves a low-viscosity curing solution without requiring petroleum-derived diluents such as styrene. Fourier-transform infrared spectroscopy confirmed the formation of a robust crosslinked network via the complete consumption of C=C bonds. Consequently, the cured resin exhibits exceptional thermal and mechanical performance, outperforming many existing bio-based analogs: a glass transition temperature (Tg) reaching 141 °C, a decomposition onset near 250 °C, and superior dimensional stability with a linear thermal expansion coefficient as low as 77 ppm/°C. Demonstrating a fully renewable, easy-to-process formulation with a flexural strength of 44 MPa, this work provides a design template for the next generation of high-performance, eco-friendly industrial thermosets.

Abstract We present results from coordinated multiwavelength observations of the microquasar SS 433, obtained with XRISM, optical telescopes (Seimei, LCO, Tomo-e Gozen, MITSuME), and the kSIRIUS near-infrared camera during 2024 April and 2025 March. The XRISM exposures amounted to ${\sim}200$ ks in 2024 and ~100 ks in 2025, corresponding to different combinations of orbital and precessional phases. With XRISM/Resolve’s high spectral resolution and large effective area, we clearly resolved numerous emission lines even in short time segments, achieving improved accuracy in Doppler-shift measurements relative to earlier observations. The simultaneously obtained X-ray and optical Doppler shifts suggest a possible tendency for the optical emission to lag slightly behind the X-rays. In the Resolve data, the Doppler shifts of the two jet components exhibited apparent asymmetries, with jet speeds fluctuating around ${\sim}0.26 \pm 0.01c$ in 2024 and ${\sim}0.30 \pm 0.01c$ in 2025. The velocity variations indicated modulations on a timescale of ~6.3 d, with a phase offset of about $-90^{\circ }$ relative to the nutation cycle. The observed line widths and flux of the approaching and receding jets appear consistent with the expected geometrical effects, indicating systematically larger line widths in the inner regions of the jets, as proposed by Shidatsu et al. (2025, PASJ, 77, 1313). Optical light curves show flares of ~400 s in 2024 and ~1600 s in 2025, with amplitudes up to ~15% during out-of-eclipse intervals, while the XRISM/Xtend light curves show no significant variability within the overlapping intervals and given the statistical uncertainties. Near-infrared photometry in 2024, obtained during an out-of-eclipse interval at a different epoch from the optical observations, showed no flare-like variability, and the X-ray band also remained constant within uncertainties. These coordinated observations provide a foundation for future XRISM studies aimed at probing the dynamical properties of the relativistic jets in SS 433.

Chemotherapeutic agents targeting ribosome biogenesis induce profound reorganization of nucleolar architecture, yet how the tumor suppressor p53 governs these structural responses remains unclear. Here, we show that loss of p53 leads to NF-κB-dependent disappearance of nucleolar caps induced by doxorubicin (DOXO). Under these conditions, fibrillarin (FBL), which is normally confined to the nucleolus, relocates to the nucleoplasm and forms foci that partially associate with G-quadruplex (G4) structures, non-canonical nucleic acid secondary structures enriched at transcriptionally active genomic regions. To examine whether this redistribution is linked to transcriptional changes, we integrated publicly available transcriptomic datasets and identified genes that were upregulated in p53-deficient cells under DOXO treatment and downregulated upon FBL depletion. Given that casein kinase 2 alpha (CK2α) is a nuclear binding partner of FBL, we further analyzed CK2α-dependent gene programs. This analysis revealed that a fraction of FBL-responsive genes overlapped with CK2α-dependent signatures and were enriched for promoter-proximal G4 structures. Among candidate regulators, the G4-binding transcription factor MAZ emerged as a potential mediator linking nucleoplasmic FBL and CK2α to G4-associated transcriptional regulation. Together, our findings identify a mechanism linking loss of p53 to G4-associated transcriptional reprogramming through nucleolar architectural disruption mediated by an FBL-CK2α-MAZ axis during DOXO treatment.