Lewis Innovative Technologies (United States)

The cell death is the most important characteristic of any tissue, including malignant tumors. It controls the proliferation and metastasis. Besides cell death determines the development of the drug resistance. In this context, the understanding of the mechanisms and searching for the targets of the alternative cellular loss can be a promising therapeutic strategy for long-term control of the tumor growth. This paper describes the mechanisms of ferroptosis, an iron-mediated non-apoptotic cell death due to lipid peroxidation. In this regard, in addition to the emergence of new therapeutic options that can affect key aspects of this process, the search for predictive markers of such metabolic therapy is also important for the clinicians.

High incidence of inoperable tumors of the gastrointestinal tract and respiratory system are required the palliative methods to restore the patency of these organs. There is also a need in case of endoscopic treatment for the I stage tumors is not possible. Photodynamic therapy is a promising method for the treatment of esophageal cancer and non-small cell lung cancer; however, despite this fact, it is still not widely used worldwide. In this article based on the literature data we review the effectiveness, safety and possibility of using endoscopic photodynamic therapy as an complementary or primary therapy for early and inoperable tumors of the gastrointestinal tract and respiratory system.

МЕТОДИЧЕСКИЕ РЕКОМЕНДАЦИИ ПО ОРГАНИЗАЦИИ МЕДИЦИНСКОЙ ПОМОЩИ БОЛЬНЫМ С НАСЛЕДСТВЕННЫМИ АТЕРОГЕННЫМИ НАРУШЕНИЯМИ ЛИПИДНОГО ОБМЕНА В СУБЪЕКТАХ РОССИЙСКОЙ ФЕДЕРАЦИИ (совместный проект

Concurrent pregnancy and papillary transitional cell carcinoma of the bladder are rare. Tumors are often discovered by ultrasound when hematuria is mistaken for vaginal bleeding or during routine obstetrical scans. This patient presented at 14 weeks gestational age with vaginal bleeding,which proved to be hematuria. At 16 weeks a maternal bladder mass was identified during routine obstetrical survey scan. Subsequent removal of mass by urologist showed papillary cell carcinoma of the bladder. This case study emphasizes the need for the sonographer to evaluate total maternal pelvic structures during routine obstetrical scans,vaginal bleeding,or when gross hematuria is present. Cystoscopy and transurethral resection are considered safe treatment during pregnancy depending on trimester and pathology results. Early detection and diagnosis produced a favorable patient outcome in this case study.

mechanism of scavenging. The plot of log E vs. log I yields a band of data lying just above the line E - 3I, which is the theoretical line for interception scavenging by spheres in potential flow. The regression line for the data is: log/sub 10/ E = 2.477 + 1.366 log/sub 10// I. The standard deviation of the residuals is 0.538. Useful presentations of the data are also achieved by using the Friedlander coordinates'', EIPe vs. IPe/sup 1/3 and EIPe vs. IPE/sup 1/2. These dimensionless groups are appropriate for scavenging due to the simultaneous action of diffusion and interception. The first pair pertains to Stokes (i.e. low speed) flow, while the second pertains to potential flow. Fortuitously, the approximate expression for interception-diffusion scavenging by spheres in potential flow fits the snow scavenging data. (auth)

Journal Article Punctuation in Mss. and printed books Get access F. W. G. Foat F. W. G. Foat 1D.Lit. Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s10-IV, Issue 86, 19 August 1905, Page 144, https://doi.org/10.1093/nq/s10-IV.86.144 Published: 19 August 1905