MantraCare

585 Background: Digital navigation platforms offer unique insights into how cancer patients seek information about their disease. Understanding these behaviors can inform the development of tailored educational resources and support services. This study examines the information-seeking patterns of patients with metastatic breast cancer (mBC) and metastatic non-small cell lung cancer (mNSCLC) using the Manta Cares digital platform. Methods: We analyzed early usage data from the Manta Cares platform, which uses a subway map structure with evidence-based disease-specific information available at each station throughout the patient clinical course. Users were recruited via patient advocacy groups, word-of-mouth, meeting presentations and social media. They provided an email, age range and cancer type information. No other personal identifying data was provided or retained. User entries were de-identified prior to analysis. While maps for early breast cancer, mBC & mNSCLC were available, this abstract focuses on the engagement patterns for metastatic patients. Results: The first 99 platform users included patient (82), care partners (3) and navigators (14). Of patients 16 self-identified as having mBC and 18 with mNSCLC. Both had similar age distribution (40-69 years). Corresponding activity for mBC and mNSCLC are shown in the table, with a total of 1,287 visits across 471 stations. There were different information-seeking behaviors between the two groups. mBC patients focused on evaluative processes (treatment assessment, disease progression) with emotional management. mNSCLC patients showed diagnostic/biomarker-oriented interest, emphasizing testing, specific treatments, and physical management. Conclusions: mBC and mNSCLC patients had different information-seeking interests. mBC patients sought treatment information and emotional support, while mNSCLC patients prioritized clinical and diagnostic content. Digital tools should be tailored to disease specific groups: emotional support alongside treatment information for mBC patients, and clinical information with . Further analyses needed to analyze engagement between early & metastatic populations. Understanding these differences can guide more effective digital resources for specific cancer patient groups. Funding: Gilead Sciences, Inc. & Manta Cares Inc. mBC & mNSCLC patient engagement. Patients mBC (n=16) mNSCLC (n=18) Overall Engagement 448 visits, 175 stations 839 visits, 296 stations Content Focus (% of Visits: Station Descriptions) Diagnosis 20%: Treatment options, Appointments, New findings 28%: Biomarker testing,NSCLC subtyping Treatment 58%: Chemotherapy options, Cancer types, Targetable mutations 42%: Therapy selection, Spread Living with cancer 22%: Understand prognosis, Living with mBC, Managing emotions 30%: Weight management, Overall well-being