McHenry County College

Climate intervention research is expanding as current mitigation efforts to limit warming below crucial targets are falling short. • Substantial knowledge gaps exist on the potential impacts of climate intervention strategies on marine ecological systems. • We review the potential impacts of climate intervention on marine ecosystems, including biotic and abiotic factors.

Introduction: This study aimed to provide a descriptive summary of body fat percentage (%BF), sum of skinfolds (SSF), and Minimum Wrestling Weight (MWW) values across all 14 weight classes among interscholastic female wrestlers in Illinois. A secondary aim was to evaluate the likelihood that 12%BF occurs among female wrestlers and assess whether the current minimum %BF threshold should be reconsidered by the sport governing body (SGB). Methods: A retrospective analysis was conducted on data from 2,291 female wrestlers during the 2023–2024 Illinois High School Association (IHSA) season. As part of mandated preseason weight certification, skinfold measurements were taken, and %BF was estimated using the Slaughter equation. Descriptive statistics and frequency analyses were used to establish normative values for %BF, SSF, and MWW. MWW and minimum weight class (MWC) were calculated using both the current minimum 12%BF standard and an alternative 19%BF threshold based on the 5th percentile of the sample. Results: The mean %BF was 29.7 ± 8.1%, with only 0.17% of athletes (n = 4) falling at or below 12%BF. On average, wrestlers were 27.2 ± 14.2 lbs. above their MWC at 12%BF and 17.7 ± 14.1 lbs. above at 19%BF. Reaching MWC would require 10.9 weeks under the 12%BF threshold versus 6.7 weeks at 19%, using the NFHS 1.5% weekly weight loss limit. The current weight distribution was negatively skewed, while the 12%BF threshold resulted in a highly positive skew. In contrast, the 19%BF threshold produced a more normalized distribution. A strong positive correlation between %BF and MWC was observed (r = 0.84, p < 0.001). Conclusion: Achieving 12%BF is improbable and rare among female high school wrestlers. Raising the minimum threshold to 19%BF may reduce harmful weight-cutting practices, improve athlete safety, and promote more equitable weight class distribution.

Kubernetes-based multi-cloud architecture is becoming an integral part of modern enterprises, which makes ensuring its security a top priority. The main threats in such a system are related to configuration management, network security, access control and compliance with regulatory requirements. For effective security management, it is proposed to use CNAPP platforms that integrate several protection mechanisms, including cloud security Management (CSPM) and Kubernetes Security Management (KSPM). Automation of monitoring processes and authentication in Kubernetes, including centralized identity and access management, play an important role. The use of encryption technologies, software-defined networks (SDN) and regular audits contribute to reducing risks. The implementation of advanced security strategies and their constant adaptation to new threats ensures the sustainability of the cyber environment of multi-cloud deployments and the maintenance of data integrity.

Political advocacy is an important religious practice. But social activism can be discouraging. This paper integrates moral theology, virtue ethics, positive psychology and spiritual formation to highlight the importance of resilient hope for social justice advocates. Part 1 describes an important justice issue—public services for disabled people. Part 2 defines transformational advocacy and outlines an advocacy theology. Part 3 analyzes despair and hope. Part 4 summarizes spiritual practices for building resilient hope.

To evaluate the equivalence of immunogenicity, safety and efficacy of Gan & Lee (GL) Glargine (Basalin®; Gan & Lee Pharmaceutical) with that of the reference product (Lantus®) in adult participants with type 2 diabetes mellitus. This was a phase 3, multicenter, open-label, equivalence trial conducted across 57 sites. In total, 567 participants with type 2 diabetes mellitus were randomized in a 1:1 ratio to undergo treatment with either GL Glargine or Lantus® for 26 weeks. The primary endpoint was the proportion of participants in each treatment arm who manifested treatment-induced anti-insulin antibodies (AIA). Secondary endpoints included efficacy and safety metrics, changes in glycated haemoglobin levels, and a comparative assessment of adverse events. Results were analysed using an equivalence test comparing the limits of the 90% confidence interval (CI) for treatment-induced AIA development to the prespecified margins. The percentages of participants positive for treatment-induced glycated haemoglobin by week 26 were similar between the GL Glargine (19.2%) and Lantus® (21.3%) treatment groups, with a treatment difference of -2.1 percentage points and a 90% CI (-7.6%, 3.5%) (predefined similarity margins: -10.7%, 10.7%). The difference in glycated haemoglobin was -0.08% (90% CI, -0.23, 0.06). The overall percentage of participants with any treatment-emergent adverse events was similar between the GL Glargine (80.1%) and Lantus® (81.6%) treatment groups. GL Glargine was similar to Lantus® in terms of immunogenicity, efficacy,and safety, based on the current study.

Background: Pulmonary embolism (PE) is a common form of venous thromboembolism that could be potentially fatal. Atrial fibrillation (AF) is the most common arrhythmia, which may lead to thromboembolic complications. They are distinct medical conditions, but PE may lead to AF through right-sided pressure overload. AF, in turn, might lead to right atrial thrombus formation and, thereby, PE. AF can be seen as a presenting sign during early phase or later during recovery from PE. Methods: This is a retrospective cohort study in which we queried the National Inpatient Sample database between 2016 and 2019 to identify hospitalizations (age 18 and older) with a principal diagnosis of Saddle embolus of pulmonary artery without acute cor-pulmonale. The cohort was divided into patients with and without AF as a secondary diagnosis. The primary outcome was in-hospital mortality. The secondary outcomes were cardiogenic shock, acute respiratory failure, length of stay, and total hospital charges. All statistical analyses were performed using weighted values. Results: During the study period, there were 58,285 hospitalizations with a principal diagnosis of Saddle embolus of pulmonary artery without acute cor-pulmonale. Among them, 5800 (11%) had a diagnosis of AF. Baseline characteristics are shown in Table 1. After adjusting for all significant baseline characteristics, patients admitted with concomitant AF had higher in-hospital mortality (6.6% vs 3.7%; aOR 1.88, 95% CI:1.46 - 2.42, p < 0.0001), cardiogenic shock (5.9% vs 2.0%; aOR 3.04, 95% CI: 2.3 - 4.0, p < 0.0001), acute respiratory failure (4.2% vs 2.7%; aOR 1.65; 95% CI: 1.14 - 2.15), increased length of stay (7.59 vs 5.44 days p < 0.0001), total hospital charges ($100,756 vs $ 69,396 p < 0.0001) Conclusions: This study demonstrates that AF is associated with increased mortality, cardiogenic shock, acute respiratory failure, length of stay, and total hospital charges in saddle embolus of pulmonary artery without cor- pulmonale