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- 10.1016/j.ejor.2024.12.026
Business cycle and realized losses in the consumer credit industry
- Jun 01, 2025
- European Journal of Operational Research
- Walter Distaso + 2 more +2
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Business cycle and realized losses in the consumer credit industry
Tannic Acid Attenuates Quinolinic Acid-Induced Neurodysfunction by Modulating Oxidative Stress Parameters and Electrogenic Pump Activity
Abstract The pathophysiology of neurodegenerative illnesses is largely dependent on oxidative stress and poor ion homeostasis, and these conditions represent a substantial worldwide health burden. Endogenous neurotoxic quinolinic acid (QA) is linked to neurodysfunction by inducing oxidative stress and interfering with sodium pump function. In a number of models, the polyphenolic molecule tannic acid (TA), which has strong antioxidant qualities, has demonstrated pharmacological effects in several diseased conditions. However, the neuroprotective effect of TA is rather speculative and still very open for clarification. In the present study, an in vitro model was employed to examine the effect of TA on deoxyribose degradation, lipid peroxidation, thiol status, antioxidant enzymes and cerebral and spinal sodium pump in rat cerebral and spinal tissue homogenates treated with quinolinic acid (QA, 2 mM). Results revealed that QA treatment led to a profound (p < 0.05) degradation of deoxyribose, formation of thiobarbituric acid reactive substances (TBARS), and marked (p < 0.05) reduction in tissue level of free thiols. However, TA treatment significantly (p < 0.05), counteracted TBARS production, deoxyribose degradation and markedly (p < 0.05) increased the thiol level of the cerebral and spinal tissue homogenates. Furthermore, QA markedly (p < 0.05) diminished the activities of cerebral and spinal antioxidant enzymes [catalase (CAT), superoxide dismutase (SOD), Glutathione Peroxidase (GPx) and Glutathione S transferase (GST)] and impaired the activities of cerebral and spinal sodium pump. Nonetheless, the activities of the antioxidant enzymes and pump were all raised in both the cerebral and spinal tissue homogenates upon TA treatment. These findings justify the pharmacological action of TA on QA-induced neurotoxicity and suggest its potential use in the treatment of neurodegenerative diseases. Further investigation is required to determine TA's translational usefulness in clinical settings.
Read moreReviews of "Accuracy of Lung and Abdominal Ultrasound for Tuberculosis Diagnosis: A Prospective Cohort Study from India"
“Dialogues of UNESCO Chairs”: The Process and the Method
Penerapan Ornamen Melayu Deli Pada Light Box Dengan Teknik Paper Cutting
Seiring berkembangnya zaman, masyarakat modern mulai meninggalkan ornamen tradisional seperti ornamen Melayu Deli. Perlunya memandang kembali budaya tradisional agar nilai-nilai luhur masyarakat Melayu Deli tidak hilang begitu saja. Sejauh ini, cara yang dilakukan masyarakat untuk melestarikan ornamen masih monoton. Proses penciptaan karya seni menurut Graham Wallas dalam buku The Art Thought (Djelantik, 2001: 64) terdiri dari: persiapan (preparation), inkubasi (incubation) inspirasi/ ilham (inspiration), elaborasi/ perluasan/ pemantapan (elaboration). Motif yang dipakai pada pembuatan karya light box ini adalah motif Roda Sula, motif Awan Semayang, motif Semut Beriring, motif Pelana Kuda Kencana, motif Itik Pulang Petang, Pucuk Kacang, motif Bunga Hutan, motif Tapuk Pinang, motif Terali Jantung, dan motif Terali Biola. Diharapkan penelitian ini dapat menjadi inspirasi dalam mengenalkan ornamen Melayu Deli dan dapat menjadi referensi untuk melakukan jenis penelitian yang sama mengenai pelestarian ornamen pada karya seni light box.Kata Kunci: Light Box, Paper cutting, Ornamen
Read moreNEUTRONIC ANALYSIS OF THE VVER-1200 LATTICE CELL FUEL USING WIMSD-5B CODE
The calculation of safety parameters in nuclear reactors has an important influence on nuclear reactor control and safety. The infinite multiplication factor, reactivity coefficients, and power peaking factor parameters are the most important safety parameters for determining reactor status. The aim of the present study is to analyze the behavior of the nuclear safety parameters for the VVER-1200 core in a normal state of reactor operation. A lattice cell fuel model of the VVER-1200 reactor core was performed using WIMSD-5B. The cross-section library data based on the ENDF/B-VIII.0 was used. The investigated parameters were the value of infinite multiplication factor with different pitch, temperature, enrichment, and boron concentration. The calculation also investigated the reactivity coefficient parameters. The verification of WIMS model VVER-1200 was performed by comparing the results of the WIMSD-5B code with VVER-1200 data in the SAR document, and it was implied that they are in good agreement. The calculated values of reactivity coefficients illustrated a safe behavior.
Read moreMENINGKATKAN ADVERSITY QUOTIENT SISWA MENGGUNAKAN AUTOGRAPH
Abstract. This study aims to determine the difference in adversity quotient between students who learn to use the Autograph learning media and students who receive conventional learning. The formulation of the problem in this study is "Is there a difference between the adversity quotient of students who learn to use Autograph learning media and students who receive conventional learning?". This research is a quasi-experimental research, where the teacher plays a direct role in the learning process and the researcher acts as an observer. The subjects in this study were students of class VIII MTs Al-Arifin Rahuning totaling 100 people and as a sample of class VIII-1 totaling 28 people. While the object of this research is the adversity quotient of students towards learning mathematics. Collecting data in this study using observation sheets and adversity quotient. To find out the results of this study, it was carried out using the t test and to determine whether or not there were differences in the adversity quotient of students towards learning mathematics. Based on the results of data analysis carried out, it was concluded that there was a difference in the adversity quotient between students who learned to use the Autograph learning media and students who received conventional learning with a tcount= 8.29 greater than ttable at the 5% significance level and significant 1% of 2.14 and 2.96.Keyword: Autograph, Adversity Quotient, Mathematic educationAbstrak. Penelitian ini bertujuan untuk mengetahui perbedaan adversity quotient antara siswa yang belajar menggunakan media pembelajaran Autograph dan siswa yang mendapatkan pembelajaran konvensional. Rumusan masalah dalam penelitian ini adalah “Apakah ada perbedaan antara adversity quotient siswa yang belajar menggunakan media pembelajaran Autograph dengan siswa yang mendapatkan pembelajaran konvensional?”. Penelitian ini merupakan penelitian eksperimen semu, dimana guru berperan langsung dalam proses pembelajaran dan peneliti bertindak sebagai pengamat. Subjek dalam penelitian ini adalah siswa kelas VIII MTs Al-Arifin Rahuning yang berjumlah 100 orang dan sebagai sampel kelas VIII-1 yang berjumlah 28 orang. Sedangkan objek penelitian ini adalah adversity quotient siswa terhadap pembelajaran matematika. Pengumpulan data dalam penelitian ini menggunakan lembar observasi dan adversity quotient. Untuk mengetahui hasil penelitian ini dilakukan dengan menggunakan uji t dan untuk mengetahui ada tidaknya perbedaan adversity quotient siswa terhadap pembelajaran matematika. Berdasarkan hasil analisis data yang dilakukan, disimpulkan bahwa terdapat perbedaan adversity quotient antara siswa yang dibelajarkan menggunakan media pembelajaran Autograph dan siswa yang mendapatkan pembelajaran konvensional denganhitung= 8,29 lebih besar dari ttabel sebesar 5 % tingkat signifikansi dan signifikan 1% sebesar 2,14 dan 2,96.
Read morePengaruh Kegiatan Lari ZigZag Melewati Balok Kayu Terhadap Kemampuan Motorik Kasar Anak di TK Aisyiyah Busthanul Athfal 01 Medan T.A 2020/2021
Penelitian Kuantitatif (Eksperimen) ini bertujuan untuk mengetahui pengaruh dari kegiatan berlari zigzag melewati balok kayu terhadap kemampuan motorik kasar anak. Sampel penelitian ini berjumlah 20 orang anak Teknik analisis data yang dilakukan pada penelitian ini adalah statistik deskriptif dan statistik nonparametrik melalui uji wilcoxon. Pengumpulan data menggunakan teknik observasi (checklist). Kegiatan lari zigzag ini dikatakan berhasil jika Ho diterima yang berarti terdapat perbedaan signifikan setelah melakukan kegiatan lari zigzag. Hasil Penelitian in membuktikan bahwa lari zigzag berpengaruh terhadap kemampuan motorik kasar anak kelompok B di TK ABA 01 Medan. Hal ini dibuktikan dengan jumlah skor anak bertambah 10,50 dilihat dari tabel analisis signed rank test. Hasil penelitian ini berpengaruh terhadap motorik kasar anak juga dapat dilihat dari pengujian hipotesis yaitu Ho diterima karena Whitung ≥ Wtabel, yang dijabarkan sebagai berikut Whitung = -46 ≥ Wttabel = 52.
Read morePENGARUH PEMBERIAN MASSAGE TERHADAP PENURUNAN KADAR ASAM LAKTAT PADA MAHASISWA ILMU KEOLAHRAGAAN SETELAH MELAKUKAN AKTIVITAS FISIK ANAEROBIK LARI SPRINT 100 METER UNIVERSITAS NEGERI MEDAN
Penelitian ini bertujuan untuk mengetahui pengaruh pemberian massage terhadap penurunan kadar asam laktat pada mahasiswa Ilmu Keolahragaan Universitas Negeri Medan setelah melakukan aktifitas fisik Anaerobik lari sprint 100 meter. Penelitian dilakukan di Fakultas Ilmu Keolahragaan Universitas Negeri Medan mulai pada bulan April-juni 2018, metode penelitian menggunakan metode eksperimen, dengan pengambilan data Pre test dan post test. Sampel penelitian berjumlah 10 orang yaitu Mahasiswa Ilmu Keolahragaan angkatan 2017 Universitas Negeri Medan. Hasil Penelitian menunjukkan ada perbedaan rata-rata kadar asam laktat pada pelari sprint 100 meter setelah pemulihan manipulasi massage pada Pre tes 4,56 pada Pos tes I 10,68 pada Pos tes II 7,38 pada Pos tes III 5,08 dan pada Pos tes IV 3,28 lebih rendah dibandingkan pada kelompok kontrol yaitu pada Pre tes 4,60 pada Pos tes I sebesar 12,86, pada Pos tes II 10,54, pada Pos tes III 8,48 dan pada Pos tes IV 6,84. Dari hasil uji ANOVA diperoleh nilai p < 0,05, yang artinya terdapat perbedaan yang bermakna (signifikan) antara penurunan kadar asam laktat pada lari sprint 100 meter mahasiswa IKOR 2017 yang diberi pemulihan manipulasi massage dan tanpa manipulasi massage. Dengan demikian dapat disimpulkan bahwa terdapat pengaruh yang signifikan manipulasi massage terhadap penurunan kadar asam laktat pada mahasiswa Ilmu Keolahragaan Universitas Negeri Medan Universitas Negeri Medan, dengan nilai p <0,05.
Read morePROJETO DE ASSISTÊNCIA INTEGRAL À SAÚDE EM DIABETES MELLITUS E HIPERTENSÃO ARTERIAL NO MUNICÍPIO DE UBERABA
A criação do Centro Municipal de Diabetes e Hipertensão do Município de Uberaba (CEMDHI) tem como objetivo a qualificação da assistência à saúde dos pacientes diabéticos, hipertensos e obesos cadastrados na rede de atenção básica de saúde do Município de Uberaba. Tem como proposta o cuidado integral dos pacientes a partir do empoderamento das equipes de Atenção Primária à Saúde (APS) e melhores condições de tratamento aos usuários com estas morbidades. Com este intuito foi elaborado um programa de educação permanente sobre estas áreas para as equipes assistenciais da Atenção Primária à Saúde (APS). Também foi implementado um processo de matriciamento abrangente e ágil dos casos. Estão sendo utilizados os recursos de telessaúde e reuniões presenciais semanais. Aplicativos digitais estão sendo desenvolvidos para conectar pacientes, APS’s e equipe do CEMDHI. O Centro Municipal conta com serviços de diabetes em adultos e crianças, diabetes gestacional, diabetes pé diabético, obesidade e hipertensão. Um fluxograma para referenciamento de pacientes ao CEMDHI e de retorno destes pacientes à APS foi elaborado.
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