MindSet Rx (United States)

This report details work conducted under the National Aeronautics and Space Administration (NASA) Hybrid Thermally Efficient Core (HyTEC) project intended to accelerate small turbofan engine turbine technologies. Pratt & Whitney (P&W) investigated continued development of two state-of-the-art combustor architectures: advanced Rich-Quench-Lean (RQL) and lean staged (LS) stoichiometry combustors. The primary objective of these investigations was to evaluate the impact of 100% blend synthetic aviation turbine fuel (SATF) on key engine and system performance metrics such as gaseous emissions, non-volatile particulate matter (nvPM) emissions, liner durability, combustor dynamics, and combustor operability, including combustion efficiency, lean blowout (LBO), and ignition characteristics.

Regenerative medicine (RM) is a fascinating area of research and innovation. The huge potential of the field has been fairly underexploited so far. Both TERMIS-AM and TERMIS-EU Industry Committees are committed to mentoring and training young entrepreneurs for more successful commercial translation of upstream research. With this objective in mind, the two entities jointly organized an industry symposium during the past TERMIS World Congress (Boston, September 8-11, 2015) and invited senior managers of the RM industry for lectures and panel discussions. One of the two sessions of the symposium-How to overcome obstacles encountered when bringing products to the commercial phase?-aimed to share the inside, real experiences of leaders from TEI Biosciences (an Integra Company), Vericel (formerly Aastrom; acquirer of Genzyme Regenerative Medicine assets), RegenMedTX (formerly Tengion), Mindset Rx, ViThera Pharmaceuticals, and L'Oreal Research & Innovation. The symposium provided practical recommendations for RM product development, for remaining critical and objective when reviewing progress, for keeping solutions simple, and for remaining relevant and persistent.