- Research Article
- 10.1016/j.talanta.2026.129497
Development of a cELISA based on a trivalent nanobody-HRP fusion protein targeting BP26 for brucellosis diagnosis.
- Jul 01, 2026
- Talanta
- Gaowa Wudong + 11 more +11
Publications from 2021 to 2026
Showing 10 of 1,133 papers
Development of a cELISA based on a trivalent nanobody-HRP fusion protein targeting BP26 for brucellosis diagnosis.
One-step synthesized NIR-responsive polydopamine nanoparticles for synergistic nitric oxide chemotherapy and photothermal therapy against multidrug-resistant bacteria.
Splicing factor SC35 inhibits Nosema bombycis proliferation by regulating the alternative splicing of Bmupp1.
Epitranscriptomic modulations optimize crop traits via messenger RNA modifications.
Rising global demand for food quantity and quality requires precision strategies on fine-tuning trait-related gene expression targeting crop improvement. Dynamic covalent modifications on mRNA add a reversible layer of post-transcriptional regulation on gene expression, yet their trait-level logic in crops remains fragmented. Recent studies connect epitranscriptomic enzymes and readers to yield components, quality traits and stress resilience. Here, we summarize regulatory mechanisms of covalent modifications emerging from 13 functionally validated crop cases across cereals, fiber and horticultural species, focusing on how m6A, m5C, m1A, ac4C, and Ψ reprogramme mRNA molecular functions, such as stability, translation, and RNA compartmentalization. We further discuss the sufficiency and insufficiency of applying current Arabidopsis-based mechanisms to crop improvements, where whole-genome duplication and paralog specialization diversify writer-eraser-reader repertoires and enable species-specific control circuits. Finally, we highlight future directions to transform descriptive maps into predictive breeding tools, emphasizing the need for quantitative, base-resolution profiling with stoichiometric accuracy and the development of programmable, site-specific perturbation systems that can test causal relationships in defined tissues and developmental stages. These advances position epitranscriptomic reprogramming as a complementary route to precision engineering of crop yield and quality.
Read moreEvolution of phage tail fiber proteins to counter bacterial resistance and improve biocontrol efficacy in plant disease models.
Chlorogenic acid promotes the degradation of advanced glycation end-products in skin via transcription factor EB mediated autophagy-lysosomal pathway
Knowledge, attitudes, and practices associated with antimicrobial use and antimicrobial resistance among livestock farmers in Botswana.
Corrigendum to "Preparedness and response to emerging veterinary disease outbreaks - A meeting report" [Biologicals 93 (February 2026) 101873
Tools and delivery technologies for mitochondrial gene editing
Synergism and antagonism mechanisms of β-carotene, γ-oryzanol, and β-sitosterol on oxidative stability of walnut oil.