Mitra Biotech (India)

Proses persalinan adalah proses di mana bayi, plasenta, dan membran dikeluarkan dari rahim. Ciri-ciri bahwa seorang ibu telah memasuki tahap persalinan meliputi kontraksi yang teratur dan semakin menyakitkan, keluarnya lendir bercampur darah dari area vagina, pecahnya kantung ketuban, dan perut yang turun sehingga membuat ibu lebih mudah bernapas. Penelitian ini dilatarbelakangi oleh berbagai metode non-medis yang mendukung ibu selama proses melahirkan, antara lain teknik pernapasan, relaksasi, pijat, posisi atau gerakan, musik, imajinasi, akupresur, serta aromaterapi. Salah satu metode pernapasan adalah contoh dari teknik non-medis yang mudah dan tidak memerlukan biaya. Tujuan dari penelitian ini adalah untuk mendapatkan gambaran implementasi pernapasan tiup-tiup dalam proses persalinan. Metode penelitian deskriptif kuantitatif dengan kohort retrospektif, lokasi penelitian di PMB Permata Hati Matesih dengan data sekunder Januari-Desember 2023. Sampel yang digunakan dalam penelitian ini sebanyak 30 responden dengan teknik sampling jenuh. Dari hasil penelitian, didapatkan bahwa mayoritas ibu bersalin berusia 20-35 tahun sebanyak 23 responden, dan ibu dengan riwayat bersalin/memiliki pengalaman bersalin sebanyak 27 responden. Tetapi, dalam implementasi pernapasan tiup-tiup dalam proses persalinan, hanya 14 dari 30 ibu yang melakukannya. Kesimpulan dari hasil penelitian ini adalah meskipun sebagian besar ibu berada pada usia dan kondisi reproduksi yang ideal, serta memiliki pengalaman melahirkan sebelumnya, penerapan teknik pernapasan tetap membutuhkan edukasi yang sistematis, latihan berulang, dan pendampingan yang konsisten.

Kanker serviks merupakan kanker terbanyak keempat di dunia, dengan morbiditas 660.000 kasus baru pada tahun 2022. Pada tahun yang sama, sekitar 94% dari 350.000 kematian yang disebabkan oleh kanker serviks terjadi di negara-negara berpenghasilan rendah dan menengah. Kanker serviks merupakan kanker terbanyak kedua pada perempuan Indonesia, dengan 36.000 kasus baru dan 21.000 kematian setiap tahunnya. Penelitian ini dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah wanita usia subur penderita kanker serviks baik rawat inap maupun rawat jalan di RSUP H. Adam Malik Medan, dengan jumlah sampel sebanyak 82 orang yang diambil dengan teknik simple random sampling. Data dianalisis dengan chi square dan regresi logistik ganda. Terdapat hubungan faktor risiko usia pertama kali berhubungan seksual (p value 0,003), riwayat penggunanaan kontrasepsi hormonal(0,002), dan jumlah pasangan berhubungan seksual (p value 0,001). Faktor risiko yang paling mempengaruhi terjadinya kanker serviks adalah penggunaan kontrasepsi hormonal (p value = 0,003) Disarankan agar tenaga kesehatan dan dapat meningkatkan edukasi dan sosialisasi kepada masyarakat tentang faktor risiko yang mempengaruhi kejadian kanker serviks dan pencegahannya

Skin is both the most visible and most environmentally exposed organ, with apparent aging phenotypes. DNA methylation clocks faithfully capture the progression of aging, but so far have been limited to training on abundant in vitro material or invasively collected samples to generate narrow methylomes using microarray platforms. Here, we demonstrate that skin biological age can be measured directly from a person's face with superior accuracy, using non-invasive tape-stripping. We developed two clocks, MitraSolo, based on single CpGs, and MitraCluster, on regions, trained on the largest enzymatic methyl-sequencing dataset of human epidermis (n = 462). Our models were validated on independent, longitudinal, and external datasets and were compared against established clocks. They predict age accurately, with an error of approximately 4 years, outperforming others on epidermal samples. They maintain high accuracy at low sequencing depths, enabling cost-effective scalability and show intra-individual prediction variation <2 years, highlighting their reproducibility. Their predictive capacity generalised across anatomical sites, conversion and sampling methodologies and on in vitro material. They also successfully captured the rejuvenating effects of Yamanaka factor treatment. MitraSolo and MitraCluster represent a new class of epigenetic clocks optimised for human skin with characteristics that support their use in clinical research, intervention monitoring, and skincare innovation.

Background: Anemia in pregnant women is a significant health concern that can increase the risk of pregnancy and childbirth complications. One of the key determinants in anemia prevention is the involvement of husbands. Objective: This study aimed to assess the improvement in husband participation in the prevention of anemia among pregnant women following an educational intervention at Hayati Clinic, Marelan, in 2025. Methods: A pre-experimental design with a one-group pretest-posttest approach was used. The sample consisted of 30 pregnant women and their husbands. The intervention included direct education and the distribution of informational leaflets. Data were analyzed descriptively and using paired t-tests. Results: The average score of husband participation increased from 2.48 to 4.14 after the intervention. All aspects of husband involvement showed a significant improvement (p &lt; 0.05). Conclusion: Educational interventions for husbands are effective in enhancing their participation in the prevention of anemia during pregnancy.

In Hindu tradition, the syllable "OM" holds significant spiritual and cultural value in Hindu tradition and is believed to produce positive psychological and physiological effects. Despite its prominence in spiritual practices, the neurophysiological basis for these benefits remains underexplored. In this study, electroencephalography (EEG), a non-invasive method for measuring electrical activity in the cerebral cortex, was employed to investigate the physical changes in brain wave patterns that occur when listening to OM chanting. Five frequency bands, namely delta, theta, alpha, beta, and gamma, are associated with brainwaves recorded through EEG, which define different states of cognitive and emotional nature. With these, this research analyzes EEG signals before and after chanting to identify and quantify changes, and to discuss the therapeutic implications. Several signal processing techniques, such as time and frequency domain analysis, assess variations in amplitude, frequency, and coherence across different brain regions. These findings show an increase in alpha amplitudes (34.2%) and an 85.4% improvement in the theta/beta ratio, related to relaxation, emotional regulation, and additional focus, as well as a decrease in beta waves, linked to stress and cognitive overload. This would show stronger neural integration between the brain hemispheres. The OM chanting evoked these results as a possible neurotherapeutic tool for stress management and cognitive enhancement. In bridging ancient spiritual practices with modern neuroscience, this study provides information on how such seemingly nonsensical meditations as OM chanting can enhance brain function, which is favorable for the third Sustainable Development Goal (SDG) of the United Nations, regarding the goal of healthy life and wellbeing throughout all ages. Further research should be done into these effects in different populations and over long periods to confirm that this is a long-term therapeutic effect.

ABSTRAK Permasalahan dalam unit kerja rekam medis di beberapa rumah sakit masih sering ditemukan, terutama terkait kurangnya monitoring dan evaluasi (monev) kinerja staf yang berdampak pada ketidakseimbangan beban kerja, kesalahan pengkodean diagnosis, serta kendala koordinasi antar staf. Tujuan kegiatan pengabdian ini adalah meningkatkan pemahaman staf rekam medis mengenai pentingnya monev sebagai upaya mendukung mutu pelayanan rumah sakit. Kegiatan dilaksanakan di RS Mitra Paramedika pada tanggal 5 Agustus 2025 dengan metode sosialisasi, diikuti oleh 10 partisipan dari unit kerja rekam medis. Tahapan kegiatan meliputi: (1) koordinasi awal dengan manajemen rumah sakit dan unit rekam medis; (2) penyusunan materi dan instrumen evaluasi; (3) pelaksanaan sosialisasi dan diskusi partisipatif; (4) pelaksanaan pretest dan posttest; serta (5) monitoring dan evaluasi tindak lanjut hasil kegiatan. Evaluasi dilakukan melalui pretest dan posttest untuk mengukur peningkatan pengetahuan, serta diskusi partisipatif untuk mengidentifikasi permasalahan aktual di lapangan. Hasil kegiatan menunjukkan adanya peningkatan pemahaman peserta sebesar 13,6% dari hasil pretest ke posttest, serta lahirnya rekomendasi perlunya instrumen monev yang lebih spesifik sesuai job description staf rekam medis, forum evaluasi rutin, serta pemanfaatan digitalisasi agar hasil monitoring lebih akurat dan mudah ditindaklanjuti. Dengan demikian, kegiatan ini berkontribusi dalam peningkatan softskill manajerial staf rekam medis dan mendukung tercapainya mutu pelayanan rekam medis yang lebih optimal. Kata kunci: rekam medis; monitoring; evaluasi kinerja; mutu pelayanan; pengabdian masyarakat ABSTRACTProblems within medical record units in several hospitals are still frequently encountered, particularly related to the lack of monitoring and evaluation (monev) of staff performance. This situation leads to an imbalance of workload, errors in diagnostic coding, and difficulties in staff coordination. The aim of this community service activity was to enhance the understanding of medical record staff regarding the importance of monitoring and evaluation as an effort to support the quality of hospital services. The activity was carried out at Mitra Paramedika Hospital on August 5, 2025, using a socialization method and was attended by 10 participants from the medical record unit. The stages of the activity included: (1) initial coordination with the hospital management and the medical record unit; (2) preparation of materials and evaluation instruments; (3) implementation of socialization and participatory discussions; (4) administration of pre-test and post-test; and (5) monitoring and evaluation of the follow-up actions. Evaluation was conducted through pre-test and post-test to measure knowledge improvement and participatory discussions to identify actual problems in the field. The results showed an increase in participants’ understanding by 13.6% from pre-test to post-test, and produced recommendations such as the need for more specific monitoring and evaluation instruments tailored to the job descriptions of medical record staff, the establishment of regular evaluation forums, and the utilization of digitalization to ensure that monitoring results are more accurate and easier to follow up. Thus, this activity contributed to improving the managerial soft skills of medical record staff and supported the achievement of more optimal quality in medical record services. Keywords: medical records; monitoring; performance evaluation; service quality; community service

Background: Stunting is a condition of growth failure in children under five caused by chronic malnutrition and recurrent infections, characterized by height or length below the standard for age. According to the 2023 Indonesia Health Survey, the prevalence of stunting is 21.5%, with the highest incidence among children aged 2–3 years. In the working area of Sinar Rezeki Community Health Center, South Lampung Regency, stunting cases remain high, reaching 723 children. Effective stunting prevention efforts require improving the knowledge and attitudes of Posyandu cadres through health promotion, one of which is by utilizing educational video media on the TikTok application. Purpose: To determine the effectiveness of health promotion through educational video media on the TikTok application towards knowledge and attitude regarding stunting prevention among Posyandu cadres. Method: This study is quantitative with a one-group pretest-posttest design. The population consisted of 80 Posyandu cadres, with a total sample of 41 respondents selected using proportional sampling. Data were collected using questionnaires and analyzed using univariate and bivariate methods, with the Wilcoxon test applied for bivariate analysis. Results: The average knowledge score before the intervention was 47.80 (SD 8.22), which increased to 71.22 (SD 7.14) after the intervention. The average attitude score before the intervention was 72.68 (SD 8.6), which increased to 91.04 (SD 3.62) after the intervention. The Wilcoxon test result showed a p-value = 0.001, indicating a significant effect of TikTok educational videos on increasing knowledge and attitudes of Posyandu cadres regarding stunting prevention. Conclusion: Educational video media on the TikTok application is effective in improving the knowledge and attitudes of Posyandu cadres towards stunting prevention in the working area of Sinar Rezeki Community Health Center. Suggestion: The use of TikTok-based educational video media should be further enhanced and implemented sustainably in health promotion programs, as it has been proven effective in improving knowledge and attitudes of Posyandu cadres in stunting prevention efforts

Farmers often have difficulty detecting pest attacks on shallots early due to limited experience and the use of manual methods that tend to be subjective. To address this issue, this study aims to develop an Android application that can detect pest attacks quickly and accurately using the K-Means Clustering algorithm. This algorithm analyzes five main plant symptoms: leaf color, leaf shape, soil moisture, leaf spots, and plant growth. The research method includes several stages, namely system requirements analysis, application design, implementation using the Java programming language and SQLite database, and testing with a black-box testing approach to ensure application functionality. In the classification process, user data is converted into numeric vectors and the distance is calculated using the Euclidean formula to three cluster centroids: Pest Free, Alert, and Pest Attacked. The application then displays the classification results directly and stores the detection history using RecyclerView. Based on manual calculations of the test data, the centroid of the “Alert” cluster shows the closest distance of 10.10 in the first iteration and gets closer to 5.05 in the second iteration after the centroid is updated. Test results show that the application can accurately classify plant conditions based on symptoms, effectively store and display detection history, and provide an easy-to-use interface that can function offline. Therefore, this application can be a useful tool for farmers in detecting pest attacks on shallots.

Background: The increasing accessibility and utility of gadgets among adolescents raise growing concerns about their impact on health, particularly sleep patterns. Excessive gadget use, especially during nighttime, has been linked to various sleep disturbances in school-aged children. Purpose: This study aimed to determine the relationship between excessive gadget use and sleep pattern disturbances among students at SMP Negeri 14 Bandar Lampung in 2024. Methods: A cross-sectional analytical survey was conducted involving 282 students from the 7th and 8th grades. Stratified random sampling was used, and data were collected using a structured questionnaire assessing gadget use and sleep quality. The Chi-square test was employed to evaluate the statistical association between the variables. Results: Among the respondents, 62.1% exhibited moderate gadget use, while 55.7% experienced moderate insomnia. The analysis revealed a statistically significant association between the level of gadget usage and the severity of sleep disturbances (p &lt; 0.001). Notably, students with high gadget use were more likely to report insomnia symptoms. Conclusion: The findings underscore a significant correlation between excessive gadget usage and disrupted sleep patterns among adolescents. Early intervention through parental guidance and institutional policies is essential to mitigate the adverse effects of gadget overuse on student health and academic performance.

High rainwater runoff in coal mining areas has a significant effect on the intensity of acid mine drainage (AMD) formation. Therefore, efforts to treat AAT during the rainy season by applying active methods must consider efficient and effective aspects. Based on these conditions, this study will analyze the aspects of using an effective dose of NaOH in neutralizing the degree of acidity (pH) of AAT and analyze the use of an effective dose of Poly Aluminum Chloride (PAC) according to environmental quality standards regulated in South Sumatra Governor Regulation No. 8 of 2012 concerning Quality Standards for Coal Mining Liquid Waste. Sampling of AAT is carried out at the inlet of the coal mining settling pond, then the AAT sample is carried out to improve quality using NaOH and PAC materials using the jar test method. The formulation of the optimum dosage of NaOH and PAC to improve the quality of AAT using linear statistical analysis with a range of water pH values of 6 - 9. The results showed that the quality of AAT at the inlet of the settling pond had an initial pH of 4.9 and TSS 3716 mgl-1 and after treatment using NaOH and PAC there was an increase in the quality of AAT with pH and TSS meeting the water quality standards that are safe to flow into the river.