National Sheep Association

Abstract The male-specific part of the Y-chromosome is in mammalian and many other species the longest haplotype that is inherited without recombination. By its paternal transmission it has a small effective population size in species with dominant males. In several species, Y-chromosomal haplotypes are sensitive markers of population history and introgression. Previous studies have identified in domestic goats four major Y-chromosomal haplotypes Y1A, Y1B, Y2A and Y2B with a marked geographic differentiation and several regional variants. In this study we used published whole-genome sequences of 70 male goats from 16 modern breeds, 11 ancient-DNA samples and 29 samples from seven wild goat species. We identified single-copy male-specific SNPs in four scaffolds, containingSRY, ZFY, DBYwithSSX3YandUTY,andUSP9YwithUMN2001,respectively. Phylogenetic analyses indicated haplogroups corresponding to the haplotypes Y1B, Y2A and Y2B, respectively, but Y1A was split into Y1AA and Y1AB. All haplogroups were detected in ancient DNA samples from southeast Europe and, with the exception of Y1AB, in the bezoar goat, which is the wild ancestor of the domestic goats. Combining these data with those of previous studies and with genotypes obtained by Sanger sequencing or the KASP assay yielded haplogroup distributions for 132 domestic breeds or populations. The phylogeographic differentiation indicated paternal population bottlenecks on all three continents. This possibly occurred during the Neolithic introductions of domestic goats to those continents with a particularly strong influence in Europe along the Danubian route. This study illustrates the power of the Y-chromosomal haplotype for the reconstructing the history of mammalian species with a wide geographic range.

Abstract. In sheep, susceptibility to scrapie is associated with the prion protein (PrP) gene polymorphism. In this study the association between selected growth traits (daily weight gain from birth to weaning and in farm fattening performance test, as well as body weight at one and two years) and PrP genotypes ARR/ARR, ARR/XXX and XXX/XXX (XXX representing AHQ, ARQ, ARH or VRQ) has been investigated in Hungarian Merino (n=286) and German Mutton Merino (n=215) rams. No significant association was found among the studied growth traits and the PrP genotypes in the Hungarian Merino breed. In case of a group of German Mutton Merino rams lamb daily gain was significantly (P≤0.05) – but in a small extent – associated with PrP genotype, which influenced the daily gain values by 9.6 %.