Nutrasource

Este artigo apresenta um relato de experiência sobre a realização de um diagnóstico situacional dos Comitês Municipais de Equidade (CME) na microrregião de Governador Valadares, Minas Gerais, no âmbito do Programa PET-Saúde: Equidade. Para a análise, utilizou-se o Planejamento Estratégico Situacional (PES), com enfoque no Momento I – Explicativo. Foram realizadas entrevistas com gestores municipais de saúde e coordenadores da Atenção Primária à Saúde, além da análise documental de normativas e registros formais dos CMEs. Os resultados indicaram a ausência de regulamentação formal, o desconhecimento do conceito de equidade por parte dos gestores e a baixa participação social nos processos decisórios. Apenas quatro dos seis municípios forneceram registros documentais, evidenciando a falta de sistematização das atividades dos CMEs. A experiência demonstrou a relevância da articulação entre ensino, serviço e comunidade para fortalecer políticas públicas voltadas à equidade em saúde. Conclui-se que a institucionalização dos CMEs, aliada à capacitação contínua dos gestores e ao incentivo à participação social, são estratégias fundamentais para a consolidação da equidade no Sistema Único de Saúde (SUS).

This study presents a novel feature-wise non-linear least absolute shrinkage and selection operator (Lasso) based technique for optimal feature selection of high-dimensional features in Partial discharges (PD) data. Laboratory conditions are employed to develop four insulation defects in medium voltage (MV) switchgear, extracting raw PD data. An experimental platform comprising a hybrid PD detection technique is employed to capture 4000 conventional and 4000 unconventional PD signals. Also, 4000 cumulative energy (CE) signals are generated from unconventional PD signals. From this dataset comprising 12000 signals, 35 typical PD features, 490 two-dimensional features, and 777 three-dimensional features are achieved. Finally, a novel feature-wise non-linear Lasso-based feature selection technique is implemented for optimal feature selection of PD data. The effectiveness of the proposed method is evaluated through different classifiers. The proposed technique demonstrates exceptional performance in feature selection for PD data in MV switchgear with the potential for application to other power system components.

Privacy concerns are rapidly growing, demanding tighter integration within the Agile software development lifecycle. Existing approaches rely on audits that are not integrated into the DevOps lifecycle, which greatly hinders both the analysis of privacy risks and the correction of privacy flaws. Even integrated tools are primarily reactive, treating privacy as an afterthought rather than a design principle. The currently used privacy engineering methodologies tend to be too general and have lackluster tooling to be enforced. Furthermore, privacy quantification is very domain-dependent, which makes it hard to automate without the help of an expert. DevPrivOps, a proposed extension to DevOps, focused on continuous privacy verification and user transparency, suffers from a lack of concrete tools. This paper proposes a novel tool for the DevPrivOps lifecycle that bridges the gap between privacy engineering methodology and the Agile planning phase, promoting the adoption of privacy by design strategies. This tool serves as a foundation for building and integrating further DevPrivOps tools, fostering a proactive approach to privacy within Agile development. We present the interface of this tool and its role in the DevPrivOps framework

Digestive health issues, including irregular bowel movements (BM) and gastrointestinal (GI) symptoms, affect millions of people in the United States and are associated with higher risks of various diseases. This randomized, double-blind, placebo-controlled study investigated the potential of Bacillus coagulans Unique IS2 to improve stool characteristics and reduce GI symptoms. Following a 2-week run-in, 144 healthy adults were randomized in a 1:1 ratio to either B. coagulans Unique IS2 (2 billion colony forming units/day) or placebo for 4 weeks. Participants were included if they had an average weekly complete spontaneous bowel movement (SBM) of ≥3.0 and <7.0 during the run-in. The primary outcome was the change in BM frequency after 4 weeks. Secondary outcomes included change in stool consistency (assessed by the Bristol Stool Form Scale), GI symptoms and quality of life, gut microbiota composition, and the proportion of complete SBM to total BM. Safety was assessed by vital signs and reports of adverse events. After 4 weeks of supplementation with Unique IS2, there was a significant increase in BM frequency ( P = 0.037). Stool consistency significantly improved after each week in the Unique IS2 group (all P < 0.05) and was significantly improved compared to a placebo after 4 weeks ( P = 0.018), driven by a significant improvement in the incidence of hard stool ( P = 0.001). There was no effect of Unique IS2 supplementation on GI symptoms and quality of life (Gastrointestinal Quality of Life Index), gut microbiota composition (analysis of stool samples by 16S rRNA), or proportion of complete SBM to total BM. Unique IS2 was safe and well tolerated over the 4 weeks of supplementation. Our results suggest that B. coagulans Unique IS2 is a promising strategy to improve stool characteristics of individuals with hard stools and poor stool quality. Clinicaltrials.gov registration: NCT05123664.

Among pesticides, paraquat (PQ) is well recognized as extremely poisonous and harmful to human health when ingested since it can damage the nervous system and induce organ failure. Increasing PQ concentrations in contaminated water and agricultural goods are currently causing concern in several countries. This article addresses an adsorbent of silicon dioxide magnetic nanoparticles (SiMNPs) that was made of magnetic bead nanoparticles (Fe3O4) decorated with silicon dioxide (SiO2), which was used to investigate PQ detection via electrochemical methods and molecular dynamics simulation. The adsorption kinetics were analyzed to optimize the adsorbent conditions via Langmuir, Freundlich, Temkin, and Dubinin–Radushkevich isotherms. The best fit through the isotherms suggested that multilayer adsorption was central to PQ detection. The obtained Freundlich isotherm had a surface heterogeneity slope of approximately 0.92 and a KF of 4.10 (L/mg) with a wide-range detection of 0.4–876 μM and a limit of detection (LOD) of 0.22 μM. With a mean free energy of 13.13 kJ/mol obtained by the Dubinin–Radushkevich isotherm, ion exchange played a role in heterogeneous adsorption. The QM/MM simulation showed that the magnetic properties of the Fe3O4 nanoparticles stabilized the protonation and deprotonation transition states of PQ. This led to conformable adsorption with two lowest adsorption states and adsorption energies of −12.2 and–10.9 kcal/mol. In an investigation of spiking recovery using a sample from a natural water source, the recovery was 83.79–103.09%. Interference tests of salts, herbicides, and phenolic pollutants were completed and revealed a high adsorption efficiency. Because of its unique properties in achieving a wide-range detection, this adsorbent with crystalline nanostructures holds significant promise for screening contaminated pesticide residues in a variety of fields. Wide-range detection with excellent recovery was proposed and demonstrated, leading to a promising path toward point-of-need (PON) portable sensor technologies used in resource-limited areas.

In recent years, artificial intelligence has been leveraged to develop an automatic question generation (AQG) system that places formative practice questions alongside textbook content in an ereader platform. Engaging with formative practice while reading is a highly effective learning strategy. AQG made it possible to scale this method to thousands of textbooks and millions of students for free. Previous research studies used aggregated data from all questions answered by all students to complete the largest evaluation of the performance metrics for automatically generated questions. However, these studies also indicated that when assigned in a classroom setting, student behavior and question performance metrics would differ. In this study, we evaluate data collected from 19 course sections taught by four faculty members at Iowa State University to gain a broader understanding of how students engage with these AI-generated practice questions when part of their university courses. Implementation strategies for the courses, student engagement, and question performance metrics are analyzed, and student feedback gathered from surveys and course evaluations are presented. Implications for further use in higher education classrooms are discussed.

Phosphorus is an essential mineral needed for the growth, maintenance, and repair of all tissues and cells. This study was designed to biofortify Pleurotus floridanus with phosphorus supplements and assessed its effect on the yield and phosphorus contents. Phosphorus supplement was added to mushroom growth media. The experiment was set in Completely Randomized Design with five replicates. The result showed a positive effect of phosphorus supplementation on the number of mushroom fruit bodies, duration to fruiting and harvesting, and wet &amp; dry weight of fruit bodies. Proximate analysis of treated samples had lower carbohydrate, higher fibre, lower lipid compared with the normal control. Phosphorus content was higher in control compared with treated samples. Conclusively, P is an essential element and it may be important to use the appropriate type of phosphate sources to ensure itsavailability.

IntroduçãoO paciente oncológico vivencia fatores estressores que perpassam a rotina de tratamento, tais como fila de espera e demora na dispensação da medicação.1,2 Diante dessas dificuldades, é importante que haja inovações tecnológicas que mapeei barreiras no processo de atendimento, proporcionando maior qualidade no atendimento em saúde. Sabendo dessas problemáticas, o estudo tem como objetivo relatar a criação de uma tecnologia – Stopwatch - que acompanha a jornada do paciente em um ambulatório oncológico.MétodoA tecnologia Stopwatch foi criada pela colaboração dos setores de enfermagem e da tecnologia da informação para identificar gargalos que causam atrasos na dispensação de medicamentos. Na primeira fase, foi realizado um mapeamento do tempo desde a manipulação do medicamento pela equipe da farmácia até sua entrega no posto de enfermagem. Os setores foram:-Farmácia Satélite -> Enfermagem: 12 minutos para liberar a punção e pré-medicação.-Farmácia Produção -> Enfermagem: 45 min para liberar quimioterapia.-Enfermagem -> Alta.Na segunda etapa, a tecnologia foi utilizada para monitorar o tempo de entrega de cada setor conforme os acordos estabelecidos. Na terceira etapa, foi implementado um painel de controle em tempo real, onde a equipe é notificada em caso de atraso, permitindo a prestação de justificativas para mapear as barreiras.ResultadoApós mapear o processo, identificamos que a farmácia satélite tinha um índice de atraso de 16,71%, enquanto a farmácia de produção registrava 19,67%. As principais causas de atraso foram dificuldade de rede venosa, liberação de múltiplos protocolos e alta demanda simultânea de pacientes. Três meses após a implantação da ferramenta, foram reduzidos para aproximadamente 9,69% na farmácia satélite e 5,61% na farmácia de produção, indicando uma melhoria significativa.ConclusãoO uso da tecnologia foi possível aprimorar o entendimento do desempenho, identificar entraves à eficiência, melhorar a motivação e facilitar a tomada de decisões através de previsões, além de diminuir o tempo de espera dos pacientes de forma segurança e com qualidade no atendimento. O Stopwatch se mostrou uma inovação que capaz de otimizar a eficiência dos sistemas de saúde, podendo ser disseminado em outros contextos de saúde.

Abstract BACKGROUND Parenteral nutrition (PN) is a safe and effective type of nutrition support. Several publications demonstrate the impact of Home Parenteral Nutrition (HPN) reducing health care costs. The question is, are HPN practices in Latin America also cost saving when compared with hospital PN? This study aimed to compare the direct costs of healthcare and non-healthcare of HPN to Hospital PN costs in Argentina through a prospective, analytical, and longitudinal, multicentre non-interventional study. MATERIALS AND METHODS Adult Patients with PN were included and followed during the last week of Hospital PN (Week − 1 before discharge), through the first week of HPN (Week + 1), and until the first month of HPN (Month + 1). Clinical, nutritional, and cost variables were recorded. Continuous variables (mean ± SD or median Q1–Q3), were tested whit T-tests or Wilcoxon signed rank test. Categorical (frequencies and percentages) were tested with the McNemar test. The total direct cost (Total Direct healthcare cost + Total Direct non-healthcare cost) from Hospital PN Week − 1 was compared with HPN Week + 1. Additionally, HPN Month + 1 was compared with an estimate of the total costs of Hospital PN Month − 1. A difference was considered significant with a two-sided p-value &lt; 0.05. Statistical analysis was performed using IBM-SPSS 26. RESULTS Forty-four patients met the inclusion/exclusion criteria and were included for analysis. Comparing HPN Week + 1 vs Hospital PN Week − 1. HPN was associated with lower total direct healthcare costs (HPN U$S 2.863,1+/-633,1 vs Hospital PN U$S 4.361,2+/-743,1. P &lt; 0,001 Mean Difference U$S − 1.498,1 CI 95% -1.203,2 : -1.789,9). Lastly, the total direct cost (healthcare and non-healthcare) was lower in the HPN setting vs. the Hospital setting for 1 week (U$S 2.987,4+/-639 vs. 4439,8+/-761,5 P &lt; 0.001 Mean Difference U$S -1.452,0 CI 95% -1.756,28 : -1.148,4). The cost reduction of HPN for 1 week was 32% (20.3% − 42.8%) and for 1 month was 36% (27.5% − 48.5%). CONCLUSIONS: HPN is cost saving compared to Hospital PN. The major cause of this cost reduction is mostly related to direct Healthcare costs.