Oniris

Adolescent dating motivations are often considered a key issue in understanding dating and sexual behaviors. Despite their initial identification, the development of these motivations and their correlates remains understudied. The present study aimed to investigate the development of dating motivations over a 3-year period using a longitudinal design, and to explore the moderating roles of romantic experiences and current dating status. French late adolescents (N = 493; 61% girls) completed a questionnaire six times over 3 years. Rooted in self-determination theory, the questionnaire assessed their amotivation for dating, intrinsic motivation (intimacy and companionship), identified regulation (pleasure and dating timetable), and external motivation (peer pressure), as well as their romantic experiences and current dating status. As expected, growth models revealed an increase in identified regulation and intrinsic motivation, and a decrease in amotivation, and external motivation between the beginning and end of high school. Gender differences emerged in the developmental trajectories of these motivations: girls showed a more rapid decline in amotivation and a steeper increase in identified regulation than boys. Furthermore, the gender gap in intrinsic motivation increased across the six waves. Overall, the findings support the view that adolescents progressively shift toward more self-determined motivations with age-a process that appears to occur earlier in girls than in boys. Romantic experiences and current dating status hindered the decrease in amotivation and made only a small contribution to the development of other forms of regulation. Practical implications of the development of dating motivation and gender differences are discussed.

Au cours de la grossesse, les changements hormonaux, biomécaniques et vasculaires contribuent au développement de troubles musculosquelettiques. La croissance de l'utérus modifie le centre de gravité du corps et la prise de poids augmente les contraintes mécaniques sur le corps. En outre, la laxité des articulations et la rétention d'eau dépendant des variations hormonales peuvent également induire des symptômes musculosquelettiques. Bien que les douleurs rachidiennes et pelviennes soient les symptômes les plus fréquemment rapportés, des troubles musculosquelettiques touchant les membres inférieurs et supérieurs peuvent également affecter les femmes enceintes. Dans cette revue, la prise en charge des affections musculosquelettiques des membres supérieurs et inférieurs survenant pendant la grossesse, c'est-à-dire de la ténosynovite de De Quervain, du syndrome du canal carpien, de la méralgie paresthésique et des affections du pied, sera décrite. During pregnancy, hormonal, biomechanical and vascular changes contribute to the development of musculoskeletal disorders. The growing uterus affects body’s center of gravity and weight gain increases mechanical stress on the body. In addition, hormonal-related joint laxity and fluid retention may also induce musculoskeletal symptoms. Spinal and pelvic pain has been reported as the most frequent complaint but other common problems consist of lower and upper limbs pain. Upper and lower limbs musculoskeletal disorders occurring during pregnancy, i.e. De Quervain's tenosynovitis, carpal tunnel syndrome, meralgia paresthetica, and foot complaints, will be described as well as their management.

Composite foods are consumed daily, but understanding their sensory properties is a major challenge. This study aims to evaluate the efficiency of Flash Profile (FP) method to characterize strawberry-filled biscuits properties, in a context of sugar reduction. Investigations were carried out on fillings (with/without added sugar, with/without strawberry aroma), then biscuits (with sugar or maltitol or sorbitol, with/without vanilla aroma) and finally on the complex fruit-filled biscuits, corresponding to a progressive matrix complexification strategy. FP allowed a discrimination of the products for the 3 matrices according to their formulation and flavouring. Fruit fillings and biscuits were described with both flavour and texture attributes, whereas fruit-filled biscuits were mainly described with texture attributes. This texture predominance could result from complex changes of texture perceived during chewing. Panellists may also have focused on the first perceived characteristics or on the product's most distinguishing features to ease the task. FP was efficient to discriminate samples in each set of samples according to formulation. The characteristics allowing differentiation between samples varied depending on the matrix. Flavour attributes were mainly used for fluid matrices while texture was dominant for solid matrices. In our study, all panellists evaluated the 3 sets of products in the same order which could have influence their evaluation of complex products during the last session. Further investigations about the evaluation of complex solid products with FP may determine if texture is always dominant, even with a lower number of products. • Flash Profile is suitable for the analysis of texturally complex foods. • Flash Profile highlights different dominant perceptions depending on matrix nature. • Fluid matrices are equally described by aroma and texture attributes. • Texture properties are predominant compared to flavour ones in filled biscuits.

Purulent vaginal discharge in dogs can originate from several causes (e.g. infections, neoplasia, anatomical defects, or foreign bodies). Vaginal foreign bodies are rare but clinically important, often leading to chronic mucopurulent or hemorrhagic discharge. Among the common foreign bodies in small animals, grass awns may induce abscesses, granulomas, or chronic inflammation. After migration, they are usually identified in subcutaneous tissues, ears, or body cavities but rarely in the genital tract. This case report describes a rare instance of chronic hemorrhagic mucopurulent vaginal discharge due to a long-retained grass awn in an ovariectomized/hysterectomized dog. Diagnosis was made based on thorough clinical workup, vaginal cytology, and ultimately confirmed by vaginoscopy; foreign body removal resulted in complete resolution of clinical signs.

This study quantifies persistent organic pollutants (POPs) in food across four territories undergoing dietary transitions: French Guiana, Guadeloupe, Senegal, and Portugal. A total of 200 local and imported food samples from 12 categories were analyzed for polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs). Concentrations varied by food matrix, region, and origin. The highest PCDD levels were found in butter from Senegal (16.64pg/g), and the highest PCDFs in leafy vegetables from Portugal (2.4pg/g). Fish category showed the highest levels of dioxin-like PCBs (600.7pg/g) and non-dioxin-like PCBs (3.6ng/g). All values complied with EU Regulation 2023/915. To estimate dietary exposure, the maximum allowable daily intake (g of food/day) was calculated using Toxic Equivalents (TEQ), EFSA's tolerable weekly intake (TWI: 2pg TEQ/kg bw/week), and compared to national food consumption data. In Portugal, exposure from fish exceeded the TWI, highlighting the influence of regional contamination sources and dietary habits.

Cell therapy is a promising approach for inducing tolerance and thus reducing the use of immunosuppressive drugs in several immune-mediated conditions. Tolerogenic dendritic cells (tolDCs) regulate antigen-specific tolerance and control the immune response, making them an interesting candidate for cell therapy. Over the last years, different human tolDCs have been generated ex vivo, each with specific phenotypic and functional characteristics. This study aims to highlight the impact of the manufacturing process on tolDC function. For that, two well-known tolDCs, autologous tolerogenic dendritic cells (ATDCs) and interleukin (IL)-10-induced dendritic cells (DC-10s), were compared based on their phenotype, metabolic secretion, transcriptomic profile, and their modulatory function. Our findings indicate that both ATDCs and DC-10s effectively regulate T cell responses; however, while DC-10s accomplish this through immune regulation, ATDCs rely on metabolic adaptations. Understanding these specific regulatory mechanisms is critically important in order to select the best disease to target using these tolDCs as cell-based therapy.