Opća bolnica Karlovac

Capillary electrophoresis with UV detection is used to monitor bromides in blood plasma, urine, and gastric juice of pigs as laboratory organisms. For analysis, 20 µL of body fluid is used, which is treated by 60 µL of acetonitrile with 2 mM KSCN as an internal standard. Separation is performed in 90 mM sodium tetraborate with the addition of 10 mM NaCl at pH 9.2. Under these experimental conditions, the migration time of bromides is 2.1 min, the limit of detection ranges from 48 to 51 µM, and the limit of quantification from 148 to 171 µM for individual body fluids. The relative standard deviation values for migration time are less than 0.1 % and for peak area in the range of 1.9–2.5 %. The developed methodology is used for time monitoring of bromides in clinical samples after intravenous administration of NaBr to a laboratory animal at a dose of 50 mg kg–1 and applied for research in the field of anaesthesiology and resuscitation.

Zbornik Nova promišljanja o djetinjstvu II / Dijete i prostor nastavak je na već započetu priču o djetinjstvu sad iz praktične vizure promatranja djeteta i prostora iz stvarnog konteksta. Na samom početku zbornika nalaze se plenarna izlaganja renomiranih znanstvenika iz odabranog područja, i to Roberte Mineo, koja problematizira ulogu okoliša i prostora u Reggio Emilia pristupu s apekta grupnoanalitičke interpretacije, Irene Klasnić koja smješta dijete i prostor u okvire pedagoškog diskursa te na kraju Laszla Varge koji problematizira neuropedagogiju ranog djetinjstva kao otvoren prozor prema svijetu. Ostali radovi zastupljeni u zborniku kategorizirani su kao stručni te daju široku tematsku lepezu veze odgojno-obrazovnog prostora sa širom društvenom zajednicom, kroz stvaralački odgojno-obrazovni potencijal životnih prostora. Nadalje, radovi prostornost dovode u vezu i s glazbenim igrama djece predškolske dobi, Orffovim instrumentarijem kao poticajem i sredstvom djetetova glazbenog razvoja, s likovnim ostvarajima koji se povezuju sa stranim jezikom. Prostor se stavlja i u kontekst poticanja tjelesnog vježbanja u odgojno-obrazovnom procesu kao ključnog čimbenika cjelokupnog djetetova razvoja, te se također ističe važnost provođenja igre na otvorenome (mozaik-pristup), osobito u ovo digitalno doba. Stoga je svakako zanimljiv rad koji se bavi suvremenom problematikom tzv. sharentinga odnosno sve većega roditeljskog izlaganja vlastite djece medijskom prostoru. Dio radova tematizira povezanost fine motorike i razvoja govora u jasličkoj dobi te djetetov doživljaj odgojno-obrazovnog prostora. S obzirom na tematske okvire koji su obuhvaćeni, a dio su stvarnog prostora, odnosno struke, vjerujemo da će ovaj zbornik pomoći u radu prije svega odgojiteljima, studentima predškolskih studija, ostalim stručnjacima i svekolikoj javnosti.

Primaljstvo je jedna od najstarijih profesija u ljudskoj povijesti, neraskidivo povezana s temeljnim životnim procesima – trudnoćom, porodom i majčinstvom. U hrvatskom kontekstu tradicija primaljstva, osobito kroz likove tzv. babica, ima duboko ukorijenjeno značenje u kolektivnoj memoriji, narodnoj medicini i kulturnoj baštini. Babice su stoljećima bile ključne osobe u lokalnim zajednicama, često jedine koje su imale znanje i iskustvo potrebno za pomoć pri porodu, osobito u ruralnim i teško dostupnim područjima. S vremenom se od samoukih, iskustveno oblikovanih babica dolazi do školovanih, zakonski reguliranih primalja i profesionalizirane zdravstvene djelatnosti. Rad prikazuje tradicijske oblike primaljske skrbi u Hrvatskoj, razvoj profesionalnog i reguliranog primaljstva te specifičnosti razvoja primaljstva na području Hrvatskog zagorja, s naglaskom na ulogu vanbolničkih rodilišta i iskustva primalja koje su radile u razdoblju prijelaza s kućnih poroda na bolničke porode. Posebno se razmatra fenomen nadriprimaljstva kao društveno-povijesnog problema uvjetovanog siromaštvom, nedostatkom zdravstvene prosvijećenosti i ograničenom dostupnošću obrazovanih zdravstvenih djelatnika. Cilj rada jest prikazati razvoj primaljske profesije u Hrvatskoj s naglaskom na nematerijalnu kulturnu baštinu te istaknuti važnost očuvanja tradicijskog znanja u suvremenom pristupu porodu i skrbi o rodiljama. Rad se temelji na analizi povijesnih i stručnih izvora te kvalitativnoj analizi svjedočanstava primalja iz Krapinsko-zagorske županije. U zaključku se naglašava da očuvanje baštine u primaljstvu nije samo čuvanje prošlosti, nego i temelj profesionalnog identiteta, humanizacije poroda i razumijevanja žene kao središta primaljske skrbi

Sewage sludge, as a by-product of wastewater treatment, represents a significant cost factor in the operation of wastewater treatment plants and accounts for up to 50% of total costs. As sewage sludge still contains a high proportion of water after the basic treatment processes (thickening, stabilization and dewatering), sludge drying helps to reduce further treatment and disposal costs. Conventional drying methods are associated with high energy consumption, making solar drying a more cost-effective alternative. This paper analyzes the economic aspects of constructing a sewage sludge solar drying facility with the help of an expert system based on neural networks. The system considers a range of parameters (plant capacity, transport distance, transport and treatment costs, etc.) to assess the values of the investment as well as the operation and maintenance costs. The analysis was carried out using NeuralTools (Lumivero). Two main options for sludge disposal were investigated: treatment at a regional center (with the sub-options of own or outsourced transport) and handing over of sludge to another legal entity. In total, five neural network models were developed based on the input load (from 75 to 10,000 t/year and from 10,000 to 20,000 t/year) and transport method (own or outsourced transport), resulting in an analysis of over 670,000 scenarios. The key output variable was the net present value of costs over a 30-year period. The results demonstrated high model accuracy (error < 5%) and allowed a comparison of the profitability of constructing a sewage sludge solar drying facility with alternative methods of sludge disposal, in particular with the transport and disposal of the dewatered sludge.

O Heydeovu sindromu riječ je kad se kod bolesnika koji imaju simptome aortalne stenoze javlja i krvarenje iz gastrointestinalnog trakta čiji je uzrok stečena koagulopatija (Willebrandov sindrom tipa 2A), što za posljedicu ima sideropeničnu anemiju. Aortalna stenoza suženje je ušća aorte. To je bolest srčanog zaliska koja se manifestira trima simptomima: anginom pektoris, zatajivanjem srca i sinkopom. Aortalna stenoza spada u degenerativne bolesti, stoga je češća u starijoj populaciji. Može biti urođena ili stečena, puno rjeđe je urođena i tada je udružena s drugim srčanim greškama.Dijagnosticiranje aortalne stenoze relativno je jednostavno pomoću ehokardiografskog pregleda srca. Međutim, pojavom krvarenja iz gastrointestinalnog trakta potreban je multidisciplinarni pristup i dodatni dijagnostički postupci. Uključivanje više specijalnosti pomaže u bržem dijagnosticiranju i adekvatnom liječenju. Nakon medikamentoznog liječenja i eventualne operacije u području gastrointestinalnog trakta, zlatni standard za bolesnika zamjena je aortalnog zaliska. Na taj način uspješno se rješavaju svi problemi koji su prisutni u kliničkoj slici aortalne stenoze i dolazi do prestanka krvarenja. Tijekom cjelokupnog procesa liječenja nezamjenjiva je uloga medicinskih sestara koje aktivnim provođenjem procesa zdravstvene njege doprinose povoljnom ishodu liječenja.

Introduction: Kinesiophobia, or the fear of movement, arises from various causes, with irrational fear of pain induced by movement playing a key role. It also includes concerns about fatigue, increased physical activity, discomfort, disease progression, and potential complications. Among patients with chronic diseases, kinesiophobia can be a crucial factor influencing their engagement in physical activity, whether in rehabilitation or leisure time. Objective: To provide an overview of the prevalence of kinesiophobia in selected chronic diseases and identify barriers affecting physical activity. Methods: A review study utilizing electronic sources from the National Medical Library, the Central Sports Library of FTVS UK, and databases such as PubMed, EBSCO, SCOPUS, Medline, and Web of Science. Results: The study summarizes the causes, manifestations, diagnostic tools, and treatment options for kinesiophobia. It maps its prevalence in patients with chronic lower back pain, ischemic heart disease, chronic obstructive pulmonary disease (COPD), multiple sclerosis, post-stroke conditions, and Parkinson’s disease. The main barriers include chronic pain, functional impairment, depression, anxiety, low educational level, and insufficient understanding of the importance of physical activity. Conclusions: Long-term avoidance of movement negatively impacts overall health. Therefore, it is essential to identify kinesiophobia and adapt treatment strategies accordingly. Raising awareness of this issue is crucial for effective and long-term successful therapy.

Probeware have been a part of science education for a relatively long time. With the support of polytechnic education, the introduction of "digital competencies" within the new informatics curriculum, and the development of the Industry 4.0 concept, working with probeware takes on an additional dimension. It is no longer just about using probeware for scientific measurements and exploring various phenomena and their principles, but also about understanding how such a probeware is constructed, how it operates, and how teachers can utilize it to develop students' competencies in areas such as: data interpretation, data structuring and visualization, modeling, coding, optimization, robotics, and more. These competencies are crucial for the proper and meaningful use of probeware not only in school but also in extracurricular practice, contributing to the development of digital and informatics literacy. In this paper, we present an open-source solution for a freely available school Probeware system MoleGraph, which can be built and subsequently used by interested parties, particularly in primary and secondary school education.

Iako rijetkost, trudnoća u dijaliziranih bolesnica izazov je koji za optimalno zbrinjavanje majke i djeteta iziskuje multidisciplinarni pristup. Povezana je s češćim razvojem preeklampsije, pogoršanjem anemije, hipertenzije i prijevremenim porodom. Smanjenju komplikacija u majke i poboljšanju preživljavanja djeteta može pridonijeti bolje razumijevanje i pravovremeno ispravljanje čimbenika povezanih s lošijim ishodima. Savjetovanje bolesnica s kroničnom bubrežnom bolešću prije začeća, izostavljanje potencijalno teratogenih lijekova, antikoagulantna terapija, kontrola arterijskog tlaka, intenziviranje i prilagodba doze dijalize, održavanje ciljnih razina hemoglobina, nutritivna potpora, optimalan ginekološki nadzor i neonatalna skrb ključne su sastavnice u terapijskom pristupu trudnoći u dijaliziranih bolesnica. Prema odabranom modalitetu bubrežnog nadomjesnog liječenja, značajno je veći udio trudnoća zabilježen u bolesnica liječenih hemodijalizom u usporedbi s peritonejskom dijalizom. Poboljšano i unaprijeđeno liječenje hemodijalizom te cjelovita skrb za bolesnice poboljšava ishode trudnoće za majku i dijete.

The first results of an analysis of the influence of temperature and precipitation on the growth of Sessile oak in the Djerdap area were obtained from two stands in colder sites. In the study of how various factors influence on radial (RW), latewood- (LW) and earlywood growth (EW) of the mentioned tree species, four methodological procedures were used: 1) correlations between three-month (seasonal) temperature and precipitation values and residual chronology, 2) correlations between monthly temperatures and precipitation and residual chronology, 3) so-called response functions and 4) correlations between the SPEI3 (integrated for 3 months) drought index and residual chronologies. A notable sensitivity of sessile oak to summer precipitation was observed, indicating that higher precipitation, particularly in July, is associated with larger growth increments and healthier trees. No significant influence of temperature on growth increments was detected, except for some correlations between seasonal (3-month) climate factors and growth. Similar to preliminary findings on the effects of precipitation and temperature on the growth of sessile oaks in warmer sites of Djerdap, a more pronounced climate signal is evident in overall radial- and latewood increments, rather than in earlywood growth. The results indicated that sessile oak trees on colder sites are significantly more resistant to the adverse effects of above-average summer temperatures than those on warmer sites in Djerdap, consistent with previous research conducted in Djerdap National Park.

V tomto článku se věnuji prezentaci jednoho aspektu výsledků svého empirického šetření pro moji disertační práci. Ve svojí práci se věnuji tématu sebereflexe. Tento jev se v průběhu druhé poloviny dvacátého století stal jednak inspirací pro různé teorie fungování sociálních jevů, ale také součástí antropologické metodologie, kde měla reflexivita demaskovat osobní vliv výzkumníka na výslednou podobu textu. Reflexivita sebou ovšem nese jisté paradoxy a problémy, které by mohly zpochybnit validitu jejího užití. Jeden z těchto problémů fungování sebereflexe v praktickém slova smyslu ilustruji v tomto příspěvku. Tvoření reflexí je zde představeno jako mechanismus tvorby identity a práce na jejích proměnách