Optimat (United Kingdom)

Abstract This paper presents a field-proven methodology that eliminates routine flaring during well testing operations. The objective is to challenge the long-standing industry practice of flaring hydrocarbons during flowback and cleanup phases, and to demonstrate that full test objectives production logging, sampling, cleanup, and data acquisition can be achieved without combustion. The case study is based on a high-H₂S gas condensate well in a remote region of Kazakhstan. To enable flare-free well testing, a novel configuration was deployed combining conventional well test equipment with a portable multiphase boosting system (BoostFlow™), capable of handling variable gas volume fractions (GVF) from 0 to 100%. Produced fluids were routed to a test separator where free water was efficiently removed, while the oil and gas phases were simultaneously pressurized and transported to a remote processing facility. This setup eliminated the need for conventional flare systems and on-site hydrocarbon handling. The operation was performed in a high-H₂S gas condensate reservoir with minimal surface infrastructure, where seamless integration of the booster into the test flowline was essential to ensure stable, controlled flowback and safe pressure management. The operation successfully achieved all standard well testing objectives, including flowback, fluid sampling, and production evaluation, while significantly reducing routine flaring. The integrated multiphase boosting system demonstrated robust performance, maintaining stable operation across a wide range of flow conditions. Notably, the unit sustained continuous operation at 100% gas volume fraction for more than 24 hours, while also delivering consistent performance under low-GVF, liquid-rich conditions. This operational flexibility enabled seamless management of transient flow regimes commonly encountered during well cleanup and test sequences. Successful execution validates the technical feasibility of eliminating flaring from well testing without compromising data integrity or operational objectives. This case provides a proven, scalable model for future applications in sour gas, gas condensate, and remote-field settings, particularly where infrastructure is limited or ESG-driven performance targets are in effect. This paper presents a well testing approach that eliminates routine flaring, challenging long-standing operational norms. Through a first-of-its-kind field application in Kazakhstan, it demonstrates that comprehensive well testing can be performed without combustion. The methodology offers practical value for operators seeking to align with ESG goals and evolving emissions regulations, while maintaining full test integrity in technically demanding, sour gas environments.

Abstract Genome-wide association studies (GWAS) have proven a powerful tool for human geneticists to generate biological insights or hypotheses for drug discovery. Nevertheless, a dependency on sensitive individual-level data together with ever-increasing cohort sample sizes, numbers of variants and phenotypes studied put a strain on existing algorithms, limiting the GWAS approach from maximising potential. Here we present in-silico GWAS (isGWAS), a uniquely scalable algorithm to infer regression parameters in case-control GWAS from cohort-level summary data. For any sample size, isGWAS computes a variant-disease association parameter in ∼1 millisecond, or ∼11m variants in UK-Biobank within ∼4 minutes (∼1500-fold faster than state-of-the-art). Extensive simulations and empirical tests demonstrate that isGWAS results are highly comparable to traditional regression-based approaches. We further introduce a heuristic re-sampling algorithm, leapfrog re-sampler (LRS), to extrapolate association results to semi-virtually enlarged cohorts. Owing to significant computational gains we anticipate a broad use of isGWAS and LRS which are customizable on a web interface.

Abstract The maintenance needs of machinery is not fixed. Reliability needs will be different from ship to ship. The aversion to risk will also be different depending on the operating context of the ships operation and its particular status at any one time. It is true that all machinery assets will be provided with a recommended maintenance schedule as defined by the manufacturer. However, in the main, the way that the machine will be operated and the context of that operation will not have been considered before the machine that leaves the factory; thus, it will not be reflected in the maintenance handbook. Apart from the period of warrantee, there is no requirement to follow the makers guidelines unless there is no other robustly considered alternative. Therefore, taking a strategic view of maintenance for any given business should be the norm.

The Journal of Alternative and Complementary MedicineVol. 2, No. 1 EditorialEditorialDaniel P. Eskinazi and Kim A. JobstDaniel P. EskinaziSearch for more papers by this author and Kim A. JobstSearch for more papers by this authorPublished Online:22 Aug 2007https://doi.org/10.1089/acm.1996.2.3AboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail FiguresReferencesRelatedDetailsCited byAcupuncture Analgesia in Patients with Postoperative Neck Pain: A Protocol for Systematic Review and Meta-AnalysisEvidence-Based Complementary and Alternative Medicine, Vol. 2022Electroacupuncture decreases inflammatory pain through a pro-resolving mechanism involving the peripheral annexin A1-formyl peptide receptor 2/ALX-opioid receptor pathway20 January 2021 | Pflügers Archiv - European Journal of Physiology, Vol. 473, No. 4Application of traditional Chinese therapy in sports medicineSports Medicine and Health Science, Vol. 3, No. 1Low back pain in athletes can be controlled with acupuncture by a catecholaminergic pathway: clinical trial20 May 2020 | Acupuncture in Medicine, Vol. 38, No. 6Medicinal Herbs: Its Therapeutic Use in Obstetrics and Gynaecology18 April 2020Electroacupuncture pretreatment attenuates brain injury in a mouse model of cardiac arrest and cardiopulmonary resuscitation via the AKT/eNOS pathwayLife Sciences, Vol. 235Nerve Stimulation: Immunomodulation and Control of InflammationTrends in Molecular Medicine, Vol. 23, No. 12Acupuncture and related techniques during perioperative period: A literature reviewComplementary Therapies in Medicine, Vol. 29Acupuncture for Migraine Prevention16 February 2015 | Headache: The Journal of Head and Face Pain, Vol. 55, No. 3Opioidergic Transmission in the Dorsal Horn29 May 2009Traditional and Evidence‐Based Acupuncture in Headache Management: Theory, Mechanism, and Practice28 June 2008 | Headache: The Journal of Head and Face Pain, Vol. 45, No. 6Acupuncture for irritable bowel syndrome: A blinded placebo-controlled trialWorld Journal of Gastroenterology, Vol. 11, No. 26Therapeutic roles of acupuncture in functional gastrointestinal disorders12 October 2004 | Alimentary Pharmacology & Therapeutics, Vol. 20, No. 8Acupuncture in pain medicine: An integrated approach to the management of refractory painCurrent Pain and Headache Reports, Vol. 6, No. 6Treatment of Pain by AcupunctureAcupuncture for Management of PainVeterinary Clinics of North America: Small Animal Practice, Vol. 30, No. 4Acupuncture: An Evidence-Based Review of the Clinical LiteratureAnnual Review of Medicine, Vol. 51, No. 1Biological mechanisms of acupunctureTropical Medicine and Traditional Methodologies: Maximizing Options for Safe and Effective Health Care Coverage25 June 2016 | Tropical Doctor, Vol. 27, No. 1_suppl Volume 2Issue 1Feb 1996 InformationCopyright 1996, Mary Ann Liebert, Inc.To cite this article:Daniel P. Eskinazi and Kim A. Jobst.Editorial.The Journal of Alternative and Complementary Medicine.Feb 1996.3-6.http://doi.org/10.1089/acm.1996.2.3Published in Volume: 2 Issue 1: August 22, 2007PDF download