Q-Peak (United States)

Current study is focused on extraction with methanol, purification, labeling with (131)I using iodogen method of the yarrow plant and investigating in vivo biological activity using biodistribution and imaging studies on healthy animal models. The aim of the study is to contribute plant extracts to discover new drugs in the diagnosis and treatment of several diseases. Nine female and nine male healthy Wistar albino rats, which were approximately 100-150 g in weight, were used for biodistribution studies. For imaging studies four healthy male Balb-C mice were used. Quality control studies were done utilizing thin layer radio chromatography (TLRC) and high performance liquid chromatography (HPLC) methods. For biodistribution studies, (131)I radiolabeled Peak 7 ((131)I-Peak 7) was sterilized and injected into the tail veil of rats and imaging studies were obtained using Kodak FX PRO in vivo Imaging System. The radiolabeling yield of each purified the bioactive extracts of the yarrow plant, seven peaks was between 79 and 92%. The highest radiolabeling yield was calculated for (131)I radiolabeled seventh peak ((131)I-Peak 7) (92.78 ± 5.04, n=5). For this reason the biodistribution and imaging studies were done for (131)I-Peak 7. That's why; these studies with Peak 7 were carried out. Peak 7 was radiolabeled with (131)I in high yield for using imaging and therapeutic studies in nuclear medical applications.

We report the first demonstration to our knowledge of broadly tunable, single-frequency operation of a cw Cr:YAG laser. Single-frequency operation was obtained from 1332 to 1554 nm with a maximum output power of 680 mW generated at 1457 nm with 10% conversion efficiency of 1047-nm pump laser radiation. A traveling-wave ring resonator was forced to operate unidirectionally by use of Faraday rotation in the Cr:YAG gain medium with a nonplanar resonator alignment, providing the required compensating polarization rotation. Tuning was accomplished with a single-plate birefringent tuning element, and single-longitudinal-mode operation was obtained by the addition of a 9.5-mm-thick uncoated CaF2 etalon. An instrument-limited single-frequency linewidth of 2.3 MHz was measured.

We have developed a quasi-CW, deep ultraviolet source producing >250 mW of 205-nm radiation. The source consists of a 100-MHz, mode-locked, 15-W, 1047-nm master-oscillator/power-amplifier, a synchronously pumped optical parametric oscillator, and three nonlinear conversion stages.

In this paper we discuss our red, green, and blue (RGB) optical parametric oscillator (OPO) light source for projection display applications. Our source consists of a diode-pumped pump laser and a LBO-based OPO. Based on our Nd:YLF gain-module design, the pump laser is frequency doubled to serve as the pump source for the OPO. The unconverted pump power is recycled as the green light for projection. The singly resonant, non-critically phase- matched OPO has, to date, generated 13 W of 898-nm signal power and an estimated 9.3 W of intra-cavity idler power at 1256 nm. With approximately 76% of pump depletion, the power of the residual green light for projection is about 5.8 W. We have extra-cavity doubled the signal to produce approximately 3.5 W of 449-nm blue light and intra-cavity doubled the idler to produce approximately 6 W of 628-nm red light. The OPO-based RGB source generates about 4000 lumens of D65-balanced white light. The overall electrical power luminous efficiency (diodes only) is about 14.6 lumens/Watt.

Summary form only given. We are developing a red-green-blue (RGB) laser-based source for projection display systems. Our design concept is to employ a high-pulse-rate, frequency-doubled Nd-doped solid state laser as the pump for a near infrared optical parametric oscillator (OPO). The OPO provides output at signal and idler wavelengths in the 900- and 1250-nm wavelength regions, respectively, which are doubled to provide blue and red wavelengths ideally suited for projection systems. The unused pump power provides the green wavelength. In this paper we report the latest results in scaling up the power of our RGB OPO to the multi-Watt level.

A compact and efficient laser source is required as an enabling technology for laser projection displays. We discuss a scalable green-pumped, non-critically phase- matched LBO optical parametric oscillator (OPO) which simultaneously generates red and blue wavelengths that are ideal for display applications. Pumping the OPO with 9.7 W of 523 nm green light from a frequency-doubled, diode-pumped Nd:YLF oscillator/amplifier laser system has resulted in a measured 4.0 W of 896 nm signal power and an estimated idler power of 2.8 W. The signal was extra-cavity frequency doubled to produce 1.10 W of blue light at 448 nm. Intra- cavity frequency doubling of the idler produced 1.95 W of red light at 628 nm.

Summary form only given. We previously reported a high-conversion-efficiency, tandem KTA-CdSe OPO source capable of covering four bands in the spectral range from 1.5 to 10 /spl mu/m. The design uses the angle-tuned, idler output of a KTA OPO to pump a non-critically phase-matched (NCPM) CdSe OPO. We use two techniques to increase the KTA OPO efficiency (1) difference-frequency generation (DFG) in a second KTA crystal placed in the KTA OPO cavity, and (2) injection-seeding of single frequency radiation at the signal wavelength into the KTA OPO cavity. We also demonstrate a tandem OPO pumped by a CW-diode-pumped, Q-switched, 4-kHz-repetition-rate, Nd:YLF laser.

Summary form only given. We describe the first demonstration, to our knowledge, of single-frequency operation from a Cr:YAG laser. The wavelength range of operation, from 1332 nm to 1554 nm, with output powers as high as 680 mW, provides a unique narrow linewidth source, potential applications include, but are not limited to, injection seeding of optical parametric oscillators for remote sensing applications such as DIAL, near-infrared spectroscopy, and optical telecommunications instrumentation.