Qatar National Library

Introduction:Sickle cell disease (SCD) is a hematological disorder characterized by sickling of red blood cells. Patients are at increased risk of venous thromboembolism. There are no guidelines for the management of venous thromboembolism in sickle cell disease specifically in terms of the anticoagulant of choice.Patient concerns:Here, we report a case of a 30-year-old lady with past medical history of sickle cell disease who came with chest pain and shortness of breath.Diagnosis:We found that she has bilateral pulmonary embolism (PE).Intervention:She was started on rivaroxaban.Outcome:The patient was followed for 18 months, she did not suffer from recurrence of PE, and she did not develop any complications related to rivaroxaban.Conclusion:We concluded that rivaroxaban is effective in treating PE in sicklers and also it is safe.

Digital libraries often need to make tweets that will attract high engagement rate. To understand this factor in relation to Qatar Digital Library (QDL), this paper will draw a comparison of tweeter feeds of QDL, British Library Labs (BL Labs) as well as Europeana Digital Library. In doing so, the paper will try to establish the reasons behind low engagement rate in the QDL tweets. So, this paper will develop steps that QDL can take so that it can increase its current number of Twitter followers and increase the engagement rate of its users. The things that QDL is failing to address will be identified by comparing the best Twitter practices from BL Labs, and Europeana digital library to that of QDL. After identifying, a recommended practices for the QDL will be provided. The practices will mainly be meant to help QDL have better Twitter engagement rate.

Background:There has been a significant improvement in both our understanding and therapeutic choices available to clinicians for the management of cancer associated thrombosis (CAT). Even with the recent publication of a systematic review and landmark trials demonstrating the non-inferiority of DOACS-based anticoagulation strategy compared to the standard of care in patients with CAT, there is unresolved uncertainty regarding the exact hierarchy of risks and effectiveness of various DOAC analogues in these cohorts of patients.Method:We will carry out a network meta-analyses, utilizing a novel generalized pairwise methodology to generate direct and indirect comparisons between the various DOAC analogues. We will search the following databases for studies that satisfies pre-specified inclusions criteria; these include PubMed, EMBASE, Cochrane library, Clinicaltrials.gov, conference abstracts among other sources. The primary efficacy and safety outcomes are recurrent VTE and major hemorrhagic events, respectively. Two reviewers will Search the databases independently with the view to identify studies that meet eligibility criteria. The methodological quality of the included studies will be determined using a recently validated risk of bias assessment tool.Results:We expect that the result of this review will ascertain the hierarchy of risks and effectiveness of various DOAC analogues in patients with CAT.Conclusion:Results of this review will assist in informed decisions making regarding therapeutic guidelines of DOAC in CAT.