Regional Museum in Teplice

To compare two dispersive ophthalmic viscosurgical devices (OVD), Z-HYALCOAT (investigational) and HEALON EndoCoat (control), with a 3-month postoperative follow-up. Multicenter study conducted in 11 sites across Europe. Prospective, randomized, masked, multicenter post market study. Adult subjects having clear intraocular media excluding the presence of cataract and scheduled for uncomplicated age-related cataract removal by phacoemulsification and IOL implantation in the capsular bag with sole administration of either investigational or control device as per randomization scheme were included in this study. Primary endpoint was the incidence of IOP ≥ 30 mmHg. Other endpoints included slit lamp observations, corneal endothelial cell density (ECD), surgeon-reported device functionality, and rate of adverse events (AEs) and device deficiencies (DDs). In total, 242 subjects were treated in this study (123 with the investigational OVD and 119 with the control OVD). In per-protocol population, 13 eyes (11.2%) from the investigational group and 19 (17.0%) from the control group reached an IOP equal to or higher than 30 mmHg at 8 hours following device use. Slit lamp examinations performed up to 3 months did not reveal any relevant differences between the groups. ECD loss was also similar between the groups. Surgeon-reported OVD functionality was generally favorable and comparable for both devices. This investigation proved the non-inferiority of Z-HYALCOAT to HEALON EndoCoat in terms of IOP spikes and showed the two devices to be highly similar in all evaluated aspects.

The article describes the discovery of a skeletal grave in 2015 in Nezabylice (NW Bohemia, Chomutov district) at a cremation burial ground, which was dated to stage B1 of the early Roman period according to characteristic metal objects. Today, only four dozen similarly dated skeletal graves are registered in Bohemia, which, together with the early date of acquisition, makes them one of the rarest and most difficult to recognize archaeological monuments in this area. In the given situation, every recently researched skeleton grave from the early Roman period brings a wealth of new and important information about this distinctive phenomenon of burial rite among the Elbe-Germanic tribes.

Purpose To compare the effect of different types of intraocular tamponade and different types of postoperative positioning on the closure of idiopathic macular hole (IMH). Methods Prospective randomized clinical trial enrolling 104 eyes of 100 patients (age, 57–87 years) undergoing MH surgery. All patients were operated on by an experienced surgeon using 25-gauge pars plana vitrectomy (PPV) and internal limiting membrane (ILM) peeling. Patients were randomized according to the type of intraocular tamponade and postoperative positioning into the following four groups: SF6 + nonsupine reading position (n = 26) (group 1), air + nonsupine reading position (n = 25) (group 2), air + prone position (n = 26) (group 3), or SF6 + prone position (n = 27) (group 4). The follow-up period was 6 months. Results MH closure was achieved in 87 eyes (83.7 %) in the overall sample after the first surgery, with closure rates of 100%, 56%, 84.6%, and 92.6% in groups 1, 2, 3, and 4, respectively. The group 2 was significantly less successful compared to the other three groups (p < 0.05). MH of sizes ≤400 µm was closed in 97.2% of cases after the first surgery, with no significant differences between groups (p = 0.219). MH with sizes over 400 µm was closed in 70.9% of cases after the first surgery, with both groups with air tamponade being significantly less successful than group 1. The nonsupine reading position was subjected to a better subjective evaluation in terms of postoperative comfort and quality of sleep, with no differences between air and SF6 tamponade tolerance. Conclusion PPV with ILM peeling, intraocular tamponade, and positioning remains the basic surgical approach in the treatment of IMH. For MH ≤ 400 µm, a high closure rate can be achieved by combining air tamponade and nonsupine reading position. For macular holes >400 µm, the greatest anatomical success can be achieved by using the SF6 tamponade in combination with the nonsupine reading position.

Phakic intraocular lenses are used to correct refractive errors. The procedure is predictable and potentially reversible. The procedure is not free of complications though. The occurrence of iris cyst after implantation of a phakic intraocular lens was not described previously in the literature. We describe two cases of iris cysts in the presence of a phakic intraocular lens; the first case describes a cyst which was not present prior to the anterior chamber phakic intraocular lens implantation. The second case describes a hidden iris cyst that affected the posterior chamber phakic intraocular lens position and lead to glaucoma.

The presence of more than 1.00 D of astigmatism in eyes implanted with diffractive multifocal IOLs has been shown to compromise corrected distance and distance-corrected near visual acuities. This was the reason that led to the development of multifocal toric IOLs. These implants have been demonstrated to provide good visual outcomes at different distances (Mojzis et al. J Cataract Refract Surg 40:60–69, 2014; Alio et al. J Refract Surg 29:756–761, 2013; Hayashi et al. J Cataract Refract Surg 36:1323–1329, 2010; Knorz et al. J Refract Surg 29:762–767, 2013, Bellucci et al. J Cataract Refract Surg 39:1507–1518, 2013; Mojzis et al. Graefes Arch Clin Exp Ophthalmol 251:341–348, 2013; Mojzis et al. J Refract Surg 27:648–657, 2011; Mojzis et al. J Cataract Refract Surg. 2015 Dec;41(12):2695-706). Recently, trifocal toric IOLs have been developed as an option to compensate for different levels of preexisting corneal astigmatism after cataract surgery and to simultaneously provide complete restoration of visual function.

The great prevalence of presbyopia and the importance of near and intermediate vision in modern society have resulted in the development of techniques to compensate this refractive condition. Moreover, as has been reported, the loss of reading skills can reduce the quality of life of presbyopic patients.