Rowan-Cabarrus Community College

Abstract Date Presented 04/06/19 The focus of the Home for Life Design (HFLD) app-based home assessment is to determine a person’s ability to safely complete an occupation in context, and if and how the environment limits safety. An inter-rater reliability study with OT students (n=32) used online training v.5; ICC between individual raters and the author was high (.92; 95% CI). These findings contribute to the evidence that the HFLD home assessment is a reliable tool for OTs making home-safety recommendations. Primary Author and Speaker: Debra Lindstrom Additional Authors and Speakers: Carolyn Sithong, Katherine Sullivan

This chapter investigates ethical dilemmas associated with early childhood education in Confucian heritage countries. It draws on literature in philosophy, psychology, sociology, and anthropology in concluding that sociocultural differences between Eastern and Western civilizations amount to an ethical dilemma, which threatens to prevent a basic epistemology as well as a pedagogy for the education of children in the context of globalization and the information technology revolution. As evidenced by inventions, innovations, developments, and other technological and scientific breakthroughs, Western learners enroll in science and technology courses. It seems as though Eastern learners are duty-bound to fulfill a national or cultural objective, which calls for studies in the science and engineering disciplines at the expense of subjects in the arts, independent of individual desire or competency.

Journeys into Darkness: Critical Essays on Gothic Horror James Goho. Lanham: Rowman & Littlefield, 2014.This collection of essays examines what author calls dread... primal fear and an ontological unease in world (3). Containing ten chapters, six of which are revisions of previously published essays, Goho explores four themes found in Gothic literature. These four include urban landscape, wilderness, manifestation of economic, social, and political anxieties and conflicts, and a voice which is given to those who suffer or experience evil (3, 4). Essays consider five American and two British authors, including Charles Brockden Brown, Edgar Allan Poe, Ambrose Bierce, Algernon Blackwood, Arthur Machen, H. P. Lo veer aft, and Fritz Leiber.According to author, all four of themes mentioned above can be found in fiction of Charles Brockden Brown. Goho states that Brown created not just American Urban Gothic, but American Gothic as a whole. Flis novels depict family disintegration and individual disintegration through collisions with uncanny (7). Goho discusses three of Brown's novels in this chapter with Wieland being an example of how isolation of wilderness can turn a family man into a killer; Arthur Mervyn being an example of how disease can turn civilized people into savages; and, Edgar Huntly being an example of how civilized man turns into a savage in wilderness, when confronted with savages who are already there (American Indians.Likewise, these four themes can be found in a variety of works that trace their beginning to Salem trials. Witchcraft, an Old World phenomenon, found fertile ground in New World among the dark, brooding side of Puritanism (163), fear of Indians and vast, potentially hostile wilderness. Attempting to escape economic, political, social, and religious injustice, colonists merely recreated New World in image of Old. He examines a number of witch narratives, such as those by Nathaniel Hawthorne, Edgar Allan Poe, Edith Wharton, Fritz Leiber, and John Updike. Anyone who reads contemporary horror fiction or watches films in genre knows that is not dead. Rather she is a continuing archetype because... [she] speaks to a primal fear. It is not fear of a witch; rather is fear of relentless and violent persecution (176) that induces us to read or watch these instantiations of Gothic.Goho analyzes four short works by prolific British writer Arthur Machen that reflect third theme of Gothic. These are Great God Pan, Inmost Light, Shining Pyramid, and White People. These stories were written in late Victorian era; all concern science and ask question, Do ends justify means? The male scientists in stories certainly believe answer is yes, and each story illustrates what they are willing to do for knowledge's sake. In each story, women are victims of horrific experiments, and, in all, these women die violent deaths. In end, says author, it is all about sacrifice of women to appease desires of men for knowledge and control (73).Algernon Blackwood's Canadian stories, according to Goho, propose that nature is wondrous but perilous (93). Stories such as Wendigo and Haunted Island reveal wilderness landscape as sublime, intensely beautiful, and awe-inspiring, but terrifying in its vastness. It harkens back to our early ancestors and their fear of dark and all that dark contained. And, speaks to fear of loneliness as well. Confronted with wilderness' majesty, one feels how truly small and alone one is. Goho believes that Blackwood's short stories yield a forest beautifully described and ... more alive and sentient than human characters (92).Whereas Blackwood presents wilderness as a backdrop upon which to expose humankind's loneliness, Fritz Leiber sets against urban landscape. …

IntroductionMutations in BRCA1/2 have been associated with increased risk for breast cancer. Recent studies indicate an association of BRCA1/2 variants with cardiovascular disease (CVD). We explored the association of missense single‐nucleotide polymorphisms (SNPs) rs1799950 of BRCA1 and rs766173 of BRCA2 with CVD phenotypes in Parsi Zoroastrians, a genetically homogenous group with high prevalence of breast cancer.MethodsAnthropometrics, blood pressure, and blood levels of lipids, uric acid and glycosylated hemoglobin (HbA1c) were measured in 144 individuals aged 20 years or older participating in a pilot study in the US. Genotyping was conducted using TaqMan assays for BRCA1‐SNP (rs1799950) and BRCA2‐SNP (rs766173). Genotype‐phenotype associations were assessed by multiple linear regression models adjusted by sex, age, sex*age and BMI using SAS 9.2 (SAS Institute Inc., NC, USA).ResultsThe mean age ± SD was 47 ± 16.7 years, and 55% were females. The genotype distribution for BRCA1 was TT (9%), TC (77%) and CC (14%) and for BRCA2 was CC (25%), AC (8%) and AA (67%). Significant associations were found between BRCA1‐rs1799950 and diastolic blood pressure and HbA1c; carriers of the minor T‐allele had lower diastolic blood pressure (73.2 ± 0.75 mmHg vs. 80.8 ± 2.3 mmHg, p = 0.001) and higher levels of HbA1c (6.4± 0.078 vs. 5.5 ± 0.2, p= 0.002) than carriers of the C allele. We also found moderate association of systolic blood pressure with BRCA2‐rs766173; homozygotes for the minor allele T had higher systolic blood pressure (134.1 ± 12 mmHg vs. 128.9 ± 16.5mmHg, p = 0.04) as compared to those with C allele. Anthropometrics, and blood levels of lipids and uric acid were not associated with the two SNPs.ConclusionDespite our small sample size, we found significant associations between the BRCA1/2 SNPs and CVD phenotypes in this genetically homogenous population of Parsi Zoroastrians. Further studies are required to confirm and validate these findings in this population.