SIT Pharmaceutical (Italy)

Oil is one of the important formulations in Ayurveda for external as well as internal use.In this study, an evaluation of the commercially available Mahamasa, Mahanarayana, sesamum oil was conducted using two different chromatographic Technique (traditional & modified pre chromatographic TLC).HPTLC is an important designing tool to evaluate the oil sample .But sampling strategy of oil in the context of traditional chromatographic method is very lengthy, costly and less convenient.Here we have modulate the chromatographic method with respect to continuous improvement plan(Kaizen approach) such as need based acceptation of saponification and paradigm shift of direct application of oil on TLC plate.Direct application of oil on plate concept adopted from pre-chromatographic derivatization, which oil sample direct applied on TLC plate and developed with suitable solvent system, and during development only unsap material will we separate on TLC plate and then compare with traditional method outcome.Separation pattern of oil on plate are same both method traditional and modified method.That means separate operation will not require for oil separation like hydrolysis of oil, extraction of unsaponifiable material and sample preparation.However modified method is less time, chemical consuming and more convenient for economically chromatographic evaluation of oil sample.

Journal Article Some Characteristics of a New Enzyme “Glycerol Oxidase” Get access Takayuki Uwajima, Takayuki Uwajima Tokyo Research Laboratory, Kyowa Hakko Kogyo Co. Ltd., Machida-shi, Tokyo Search for other works by this author on: Oxford Academic Google Scholar Hiroko Akita, Hiroko Akita Tokyo Research Laboratory, Kyowa Hakko Kogyo Co. Ltd., Machida-shi, Tokyo Search for other works by this author on: Oxford Academic Google Scholar Kunio Ito, Kunio Ito Pharmaceutical Laboratory, Fuji Factory, Kyowa Hakko Kogyo Co., Ltd., Nagaizumi-cho, Shizuoka-ken Search for other works by this author on: Oxford Academic Google Scholar Akira Mihara, Akira Mihara Tokyo Research Laboratory, Kyowa Hakko Kogyo Co. Ltd., Machida-shi, Tokyo Search for other works by this author on: Oxford Academic Google Scholar Kazuo Aisaka, Kazuo Aisaka Tokyo Research Laboratory, Kyowa Hakko Kogyo Co. Ltd., Machida-shi, Tokyo Search for other works by this author on: Oxford Academic Google Scholar Osamu Terada Osamu Terada Tokyo Research Laboratory, Kyowa Hakko Kogyo Co. Ltd., Machida-shi, Tokyo Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 43, Issue 12, 1 December 1979, Pages 2633–2634, https://doi.org/10.1080/00021369.1979.10863875 Published: 01 December 1979 Article history Received: 05 September 1979 Published: 01 December 1979

Journal Article A Procedure for Estimating the Racemisation of Adrenaline or Noradrenaline in Dilute Solution by Means of an Ion Exchanger Get access Hans Hellberg Hans Hellberg Chemical Department, the State Pharmaceutical Laboratory, Stockholm Search for other works by this author on: Oxford Academic Google Scholar Journal of Pharmacy and Pharmacology, Volume 7, Issue 1, August-September 1955, Pages 191–197, https://doi.org/10.1111/j.2042-7158.1955.tb12025.x Published: 12 April 2011 Article history Received: 27 October 1954 Published: 12 April 2011

Journal Article THE PROPERTIES AND REACTIONS OF SOME METHONIUM COMPOUNDS Get access I E Balaban, I E Balaban Pharmaceutical Laboratory, The Geigy Company, Ltd., Trafford Park, Manchester, 17 Search for other works by this author on: Oxford Academic Google Scholar J A Beton J A Beton Pharmaceutical Laboratory, The Geigy Company, Ltd., Trafford Park, Manchester, 17 Search for other works by this author on: Oxford Academic Google Scholar Journal of Pharmacy and Pharmacology, Volume 3, Issue 1, September 1951, Pages 360–367, https://doi.org/10.1111/j.2042-7158.1951.tb13076.x Published: 12 April 2011 Article history Received: 03 April 1951 Published: 12 April 2011

1. Calves subjected to a natural infection proved to be immune against subcutaneous inoculation of virulent blood carried out 20-34 days after their recovery. To determine the duration of the immunity produced by the natural infection further investigations are necessary.2. Subcutaneous inoculation of blood, saliva, vesicular content, and emulsion of spleen and lymphatic gland from an infected animal produced the disease in the calves experimented on. The minimum dose of virulent blood for a calf was 2c.c.3. The blood-serum taken from the animal recovered from one attack of this disease was found to have a protective action which can be intensified by repeated injections of the virulent blood (100, 500, 1000c.c.)4. The period of incubation in this disease is sometimes as short as 24 hours. To test, therefore, the protective action of an immune serum, injection of serum first and of virus one or two days later is preferable to the injection of both at the same time.5. The animals treated with the immune serum in a dose of 0, 53c.c. per kilo body-weight proved to be immune against injection of 10c.c. of virulent blood carried out 3 weeks later. To determine the relation between the dose of serum and the duration of immunity further investigations are necessary.