ScienceScope (United Kingdom)

It can be concluded that digital services can certainly add value to mental healthcare; however, the sustainable integration into care is linked to improvements in structural conditions (such as the cost-benefit ratio and better information for those providing treatment) as well as consideration and compensation for socially unequal access conditions.

This “Wortfeld” (lexical field) contains the different Latin terms that refer to the senses in the visionary work Scivias of Hildegard of Bingen. These terms are ordered according their syntactic function and their sensory meaning is highlighted using different lexica.

Background:The muscle splitting technique is a submuscular pocket used for augmentation mammoplasty. Its use and results following primary and secondary procedures are presented.Methods:A retrospective study that analyzed complication and revision rates following primary and secondary mastopexy with augmentation in a muscle splitting pocket performed between April 2007 and March 2020 was carried out. Data were divided into two groups: primary and secondary single-stage mastopexies with augmentation.Results:A total of 169 patients had a primary procedure and 49 had secondary procedures. The mean ages of patients in the primary and secondary were 32.3 ± 9.89 and 38.2 ± 9.63 years, respectively. Five (3.0%) patients had periprosthetic or wound infections in the primary group when compared with 0% in secondary surgery group. Wound breakdown was seen in 13 (7.7%) patients with a primary procedure compared with one patient (2%) with a secondary procedure. One patient had partial nipple loss and another had total nipple loss in the primary group (1.2%) when compared with one patient (2.0%) who had partial nipple loss in the secondary group. Revision surgeries were carried out in 16 (10.1%) of the primary procedures compared with five (10.2%) of the secondary procedures.Conclusion:Even though there was a higher prevalence of complications in the primary procedures group than in the secondary procedures group, the overall complications following muscle splitting mastopexy with augmentation are within an acceptable range.

Abstract The purpose of this note is to establish isomorphisms up to bounded torsion between relative $K_{0}$-groups and Chow groups with modulus as defined by Binda and Saito.

This Symposium presents curriculum design and content issues in a Scandinavian business school at its Centenary. The aim is an exploration of an educational institution at the interface of the Euro...

Urlaubsreiseverhalten und Kurzurlaubsreiseverhalten. Urlaubsmotive und Urlaubsinteressen. Themen: Anzahl der Urlaubsreisen im Jahr 2010 ab 5 Tagen Dauer, von Kurzurlaubsreisen (2-4 Tage Dauer) und von sonstigen Reisen mit wenigstens einer Übernachtung; Urlaubsansprüche und Urlaubsaktivitäten; detaillierte Angaben in Form eines Jahresschemas über alle mehr als fünftägigen Urlaubsreisen im Jahr 2010, wie z.B. Reiseziel, Erstaufenthalt in diesem Reiseziel, Reisedauer, Organisationsform, wichtigstes Verkehrsmittel, Unterkunftsart, Reisebegleitung, Anzahl und Alter mitgereister Kinder, Reiseausgaben und Urlaubsreisearten (Aktivurlaub, Erlebnis-Urlaub, Ausruh-Urlaub, Sightseeing-Urlaub, Natur-Urlaub, Strandurlaub, Gesundheits-Urlaub, Studienreise, Kulturreise, Rundreise, Familien-Ferien, Verwandten- bzw. Bekanntenbesuch, Spaßurlaub); Reiseart und Wichtigkeit der Haupturlaubsreise; Reiseziele in ausgewählte Länder und Regionen in Europa, außereuropäisches Mittelmeer, Fernziele, Übersee und in Deutschland während der letzten drei Jahre; geplante Reise in diese Urlaubsgebiete in den nächsten drei Jahren bzw. Wahrscheinlichkeit einer solchen Reise; Häufigkeit ausgewählter Urlaubsaktivitäten in den letzten drei Jahren (z.B. sportliche Aktivitäten, Ausflüge, Ausruhen, Wintersport, Angeln, Golf, Wellness usw.); präferierte Urlaubstypen während der letzten Jahre und zukünftig geplante Urlaubstypen; in den letzten drei Jahren durchgeführte und zukünftig geplante Urlaubsformen (Fitness-Urlaub, Kur im Urlaub, Gesundheitsurlaub, Wellnessurlaub, Club-Urlaub, Kreuzfahrt auf See, Studienreise, Städtereise, Kulturreise, Rundreise); in den letzten drei Jahren durchgeführte und zukünftig geplante Urlaubsangebote bzw. Unterkunftsformen und Transportmittel (Ferienwohnung bzw. Ferienhaus, Camping-Urlaub im Zelt, Wohnwagen oder Wohnmobil, Ferienzentrum bzw. Center Parc, Bauernhof, Busreise, All-Inclusive-Reise); Urlaubsinteresse; Reiseabsicht 2011; Internetzugang; Nutzungsintensität des Internets; Internetnutzung für die Informationsbeschaffung und Buchung von Urlaubsreisen; Anzahl der Urlaubsreisen 2008 und 2009 von jeweils 5 Tagen oder länger. Demographie: Geschlecht; Alter des Befragten und des Haushaltsvorstands; Familienstand des Befragten und desHaushaltsvorstands; Befragter ist Haushaltsvorstand; Befragter ist haushaltsführende Person; Schulbildung, Berufstätigkeit und berufliche Stellung des Befragten und des Haushaltsvorstands; Haushaltsgröße; Anzahl der Personen im Haushalt ab 14 Jahren; Kinder im Haushalt und Alter der Kinder; Haushaltsnettoeinkommen; PKW-Besitz im Haushalt; Einkommen des Befragten; Staatsangehörigkeit (Migrationshintergrund). Indices: Soziale Schicht; Lebensphase. Zusätzlich verkodet wurde: Bundesland; Herkunft West/Ost; Ortsgröße; Nielsengebiet; Gewichtungsfaktor.

There is growing evidence for a causal role of the KDM5 family of histone demethylases in human cancer. In particular, KDM5A (JARID1A/RBP2) and KDM5B (JARID1B/PLU1) contribute to cancer cell proliferation, reduce the expression of tumor suppressor genes, promote the development of drug tolerance and maintain tumor-initiating cells. KDM5 enzymes remove tri- and di-methylations of lysine 4 of histone H3 - modifications that occur at the start site of transcription in actively transcribed genes. However, the importance of the histone demethylase activity of KDM5 proteins for cancer cells has not been resolved so far. The currently available approaches suppress or remove the targeted proteins and thereby affect their putative functions as structural components and recruitment factors for other chromatin-associated proteins. Therefore, the development of specific enzymatic inhibitors for KDM5 will promote our understanding of the biological role of their catalytic activity and yield potential novel anticancer therapeutics.

Both Freud and Lacan have made love the object of scientific enquiry, which is in itself remarkable, since we usually turn this subject over to literary and philosophical treatment. This article discusses Freud and Lacan’s contributions to the psychology of love through dialogue with Marcel Proust’s seminal novel, Remembrance of Things Past, with special emphasis on the middle sections. The point of departure is love’s manifestation in the analytical situation. Freud has described transference love as both resistance and as an extreme variant of normal falling in love, to which Lacan adds the deceptive character of transference. From transference love the investigation continues to the contradictions Freud has described in Three Essays on the Theory of Sexuality as love’s affectionate and sensual currents. Lacan contributes the concept of desire, which must be distinguished from drive and love. The differentiation between desire, drive and love introduces the perspective necessary for a psychoanalytic reading of Proust’s opus. The main objective is a reading of the protagonists, Albertine and the Baron de Charlus, as representatives of the vicissitudes of love and drive, respectively.