Spiro Medical (Norway)

<p>This report has been produced within the EMPIR project entitled <em>Traceable Mechanical and Electrical Power Measurement for Efficiency Determination of Wind Turbines</em> or <em>19ENG08 WindEFCY.</em> More information about this collaborative research project can be found on the project’s website <a href="https://www.ptb.de/empir2020/windefcy/home/">https://www.ptb.de/empir2020/windefcy/home/</a>. This report aims to investigate the multitude of influencing variables and the changing boundary conditions for measurements to determine the efficiency of wind turbines. Moreover, through a systematic comparison of direct and indirect efficiency determination methods for rotating electrical machines, the challenges for designing an efficiency determination procedure for nacelles and their components on test benches is examined.</p>

Sistemas de Controle em Rede, ou Networked Control Systems (NCS), são amplamente utilizados na Indústria 4.0 e no controle de infraestruturas críticas. No entanto, ao mesmo tempo em que oferecem diversas vantagens, os NCSs são propensos a ataques cibernéticos. Este trabalho investiga novas classes de ameaças em NCSs (ataques de Identificação de Sistemas e ofensivas furtivas/baseadas em modelos) e propõe novas contramedidas para mitigá-las. Os resultados indicam que o estudo dos novos ataques apresentados neste trabalho e as contramedidas aqui propostas contribuem para a segurança cibernética dos NCSs.

<p>The production of selenium and selenomethionine certified reference material in yeast (<em>Saccharomyces cerevisiae</em>) and certification studies for its homogeneity, stability and characterization, have been accomplished before in our laboratory. Based on such results and experience of our laboratory in Metrology and according to literature, we discuss here the advantages and limitations of the calibration by “single point” as an alternative method to the classical calibration curve. The method traceability to the SI is checked in order to secure a robust determination. As the model analyte the mass fraction of the Se species selenomethionine is measured and compared in yeast samples. Results showed that a good agreement was obtained by both methods (the reference one of the calibration curve and “single point calibration”). This simple approach can be used for routine control of selenomethionine in commercial supplements of yeast samples, but the work carried out demonstrated its potential for the general routine quantitative analysis of the possible and important selenium species in other Se-enriched supplements commercialised in Latin America (i.e. mushrooms, garlic etc).</p>

Phosphate saline buffer (PBS) and glycine buffer (GB) were evaluated as elution buffers in an adsorption-elution method using a negatively charged membrane associated with quantitative polymerase chain reaction (qPCR) and seminested PCR for detection of Norovirus genogroup II (NoV GII) from lettuce. In this methodology, PP7 bacterio-phage was used as a virus sample for process control. The qPCR showed more sensitivity than semi-nested PCR for NoV GII detection. The recovery efficiency, using PBS and GB, ranged from 24.72 to 60.78% and 19.48 to 137.26% for NoV GII, and from 0.01 to 0.15% and 0.13 to 6.04% for PP7 bacteriophage, respectively. Elution with GB was more effi-cient for PP7 bacteriophage recovery (p = 0.03), but no difference was seen for NoV GII (p = 0.57). The GB performed better than PBS as an eluent solution and can be consid-ered a methodological improvement.

O trabalho aborda um estudo comparativo entre a técnica de Cromatografia a Líquido de Alta Eficiência e a técnica de Calorimetria Exploratória Diferencial, visando avaliar a aplicação desta para a determinação direta da pureza de fármacos candidatos a materiais de referência certificados.

We compared risk-adjusted mortality rates between Medicaid-eligible patients in the Medicare Advantage plans ("MA dual enrollees") and Medicaid-eligible patients in the Veterans Health Administration ("VHA dual enrollees"). We used the Death Master File to ascertain the vital status of 1912 MA and 2361 VHA dual enrollees. We used Cox regression models to estimate hazard ratios (HRs) with 95% confidence intervals (CIs). The 3-year mortality rates of VHA and MA dual enrollees were 15.8% and 19.0%, respectively. The adjusted HR of mortality in the MA dual enrollees was significantly higher than in the VHA dual enrollees (HR, 1.260 [95% CI, 1.044-1.520]). This was also the case for elderly patients and those from racial/ethnic minority groups. The VHA had better health outcomes than did MA plans. The VHA's performance is reassuring, given its emphasis on equal access to healthcare in an environment that is less dependent on patient financial considerations.