Splošna Bolnišnica Slovenj Gradec

Izhodišča: Prehransko stanje posameznika uvrščamo med ključne dejavnike njegovega zdravja. Za učinkovito individualno in multidisciplinarno obravnavo stanj, povezanih s prehranskim stanjem posameznika, moramo dobro poznati terminologijo klinične prehrane. Ker je klinična prehrana kot medicinska stroka razvita tudi pri nas, v tujini pa so tovrstni terminološki dokumenti že na voljo, želimo tudi v Sloveniji na podlagi konsenza oblikovati enotno terminologijo. Metode: Prispevek je osnovan na podlagi eksplicitnega terminološkega dogovora. K sodelovanju smo povabili obsežno skupino relevantnih slovenskih strokovnjakov s kliničnih, predkliničnih in drugih področij, ki so povezana z dejavnostjo klinične prehrane v medicini, pri oblikovanju pa je sodeloval tudi terminolog s področja medicine. Kot izhodišče smo izbrali terminološke smernice Evropskega združenja za klinično prehrano in presnovo ter ob njih upoštevali najnovejša strokovna priporočila za posamezne pojme. Avtorji so bili v stiku prek osebnih srečanj in elektronske pošte. Pri končnem oblikovanju konsenza je sodelovalo 42 avtorjev iz 19 slovenskih ustanov. Rezultati: Predstavljamo temeljne pojme, terminološke definicije in pripadajoče slovenske termine s področja klinične prehrane. Opredelili smo osnovne motnje prehranjenosti – podhranjenost, prekomerno hranjenost, neravnovesje mikrohranil in sindrom ponovnega hranjenja. Poleg tega smo opredelili tudi s prehranjenostjo povezana stanja – sarkopenijo in krhkost. Osnovne pojme smo podprli s kliničnim kontekstom, v katerem nastopajo. Zaključki: Poenoteno razumevanje osnovnih patoloških stanj, ki jih obravnava klinična prehrana, je izhodišče za nadaljnji razvoj stroke, poleg tega pa je podlaga tudi za prehransko obravnavo in učinkovito prehransko oskrbo.

Резиме: На аутопутевима, као високо капацитивним саобраћајницама у стањима високих, односно вршних оптерећења, у принципу, јављају се уска грла на наплатним станицама и граничним прелазима.Проблем елиминације ударних таласа и енормних временских губитака који се повремено појављују на овим елементима аутопутског система мора бити заснован на детаљнијој анализи саобраћајних токова.У овом раду анализиране су промене просечног годишњег дневног саобраћаја (ПГДС) на постојећим аутопутским граничним прелазима Републике Србије у протеклих десет година.На основу детаљне анализе у раду су извучени закључци и трендови на основу којих су представљене пројекције вредности ПГДС-а на аутопутским граничним прелазима који ће бити изграђени у будућности.Основ за ову анализу су реални подаци

Objective: To evaluate an association between the mode of conception and preterm delivery in women after reproductive surgery, and to explore an effect of reproductive surgery on preterm delivery. Design: Prospective cohort study and historical case-control study. Setting: Division of Obstetrics and Gynecology, Ljubljana, Slovenia. Population or sample: A cohort of 761 infertile women after reproductive surgery. Methods: In infertile women, we evaluated the association between the mode of conception and preterm delivery using logistic regression adjusted for relevant co-variables. In a case-control study, we evaluated the effect of reproductive surgery on preterm delivery using propensity score method. We calculated the adjusted odds ratios with a 95% confidence interval with a two-way test. Main Outcome Measure: Preterm delivery. Results: Among 761 infertile women, 428 (56.2%) conceived spontaneously, and 333 (43.8%) conceived after IVF/ICSI. The incidence of twin pregnancies was significantly lower after spontaneous conception (2.6% vs. 14.1%; p <0.000). Adjusted logistic regression analysis in singleton pregnancies disclosed no significant association between the mode of conception and preterm delivery. Compared with fertile women, the incidences of preterm deliveries < 37, and < 32 gestational weeks were higher in infertile women (11.2% vs. 14.2%, and 1.7% vs. 2.6%, respectively). However, the differences did not reach a statistical significance (p=0.076 and p=0.218, respectively). Conclusion: In selected infertile women after reproductive surgery, a high rate of spontaneous conception, a low rate of multiple pregnancies, and no treatment-related adverse effect on preterm delivery should be the reasons to encourage spontaneous conception after reproductive surgery.

Turtles are common as pets and represent a known reservoir for salmonellosis. There are few epidemic outbreaks of salmonellosis linked to ingestion of undercooked turtle meat described in the literature. A few cases of pet turtle borne infection and infection due to aquarium water contamination have been described. We present cases of two female patients hospitalized due to acute gastroenterocolitis caused by Salmonella Chester and the epidemiological report of events related to the infection outbreak. The infection was transmitted from the water of a private aquarium with two pet turtles.

BackgroundTMPRSS2:ERG gene aberration may be a novel marker that improves risk stratification of prostate cancer before definitive cancer therapy, but studies have been inconclusive.MethodsThe study cohort consisted of 202 operable prostate cancer Slovenian patients who underwent laparoscopic radical prostatectomy. We retrospectively constructed tissue microarrays of their prostatic specimens for fluorescence in situ hybridization, with appropriate signals obtained in 148 patients for subsequent statistical analyses.ResultsThe following genetic aberrations were found: TMPRSS2:ERG fusion, TMPRSS2 split (a non-ERG translocation) and ERG split (an ERG translocation without involvement of TMPRSS2). TMPRSS2:ERG gene fusion happened in 63 patients (42 %), TMPRSS2 split in 12 patients and ERG split in 8 patients. Association was tested between TMPRSS2:ERG gene fusion and several clinicopathological variables, i.e., pT stage, extended lymph node dissection status, and Gleason score, correcting for multiple comparisons. Only the association with pT stage was significant at p = 0.05: Of 62 patients with pT3 stage, 34 (55 %) had TMPRSS2:ERG gene fusion. In pT3 stage patients, stronger (but not significant) association between eLND status and TMPRSS2:ERG gene fusion was detected. We detected TMPRSS2:ERG gene fusion in 64 % of the pT3 stage patients where we did not perform an extended lymph node dissection.ConclusionsOur results indicate that it is possible to predict pT3 stage at final histology from TMPRSS2:ERG gene fusion at initial core needle biopsy. FISH determination of TMPRSS2:ERG gene fusion may be particularly useful for patients scheduled to undergo a radical prostatectomy in order to improve oncological and functional results.

Various volume functions used for tree volume estimations were compared by the authors. Using section measurements (Newtonʼs method), they calculated the real tree volumes of 88 felled spruce trees on the Pokljuka plateau. The real tree volumes were used to form regional three-entry volume functions, (two-entry) volume tables, and tariff functions. The standard error of the average tree volume estimation is the lowest for three-entry volume functions (5.0%), then for volume tables (11.7%), and the highest for tariffs (15.1%). The reliability and applicability of the developed regional and other volume functions was verified on two one-hectare research plots. It was established that by applying the adapted German volume tables, the measured spruce volumes were too high. As the volumes measured in this manner are used when determining the adapted tariffs in Slovenia, this procedure results in a tariff class of at least 5% too high tree volumes.

It has been shown that pulsed wave tissue Doppler velocities of mitral annulus correlate well with left ventricular (LV) diastolic and systolic functions. It is not yet clear whether these velocities can be used to estimate left ventricular dysfunction in an unselected population of patients with clinical signs and symptoms of heart failure (HF). To determine whether LV mitral annulus velocities measured by tissue Doppler imaging (TDI) correlate with plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in patients with HF. Early diastolic (E(m)) and systolic (S(m)) TDI velocities of septal and lateral mitral annulus were measured in 50 patients with HF together with other conventional echocardiographic parameters, and compared with plasma NT-proBNP levels. Significant correlations were found between NT-proBNP level and E(m) velocity (r=-0.79), S(m) velocity (r=-0.43), early transmitral to E(m) velocity ratio (r=0.38), LV end diastolic diameter (r=0.29), LV ejection fraction (r=-0.44) and tricuspid regurgitant velocity (r=0.31). In multiple regression model (R(2)=0.733), the E(m) velocity was the most important predictor of NT-proBNP level. Early diastolic mitral annulus velocity measured by TDI correlates strongly with plasma NT-proBNP levels, and provides a simple, accurate and reproducible echocardiographic index of heart failure.

Background. The evaluation of neonatal outcome after delivery is being performed since 1953 by Apgar score. Since some parts of this scoring system subject to personal judgment of the evaluator, the researchers attempts are to introduce more objective method of determining neonatal outcome after delivery. Determining umbilical artery pH value is one of such attempts. Methods. We established umbilical artery blood pH value in 146 newborns after cuting umbilical cord following delivery. The same newborns were evaluated by Apgar score. By analysis of the variance both evaluating methods of neonatal outcome were compared regarding their ability to predict neonatal indisposition for duration of hospitalization. Neonatal morbidity and neonatal hospitalization duration were the criteria for neonatal indisposition. Results. Apgar score value following 5th minute after delivery is importantly linked with neonatal morbidity and neonatal hospitalization duration. Conclusion. Umbilical artery blood pH value can’t be used as a substitute to Apgar score. Apgar score after 5th minute is the sole predictor of neonatal outcome.<br /><br />