St. Theresa’s Multi-Speciality Hospital

A more efficient and ecologically friendly method has been devised for the preparation of α-amino phosphonates by Kabachnik-Fields (K-F) reaction in a solvent-free environment using an ultrasonication technique catalyzed by nano ZnO. Primarily, an in silico ADMET and molecular docking analysis was carried out on each molecule prior to synthesis to get insight into drug-likeliness behavior and their capacity to inhibit α-amylase and α-glucosidase. The structure of the newly synthesized compounds was confirmed using spectroscopic analysis, and each one’s in vitro inhibitory action against α-amylase and α-glucosidase was evaluated. The compounds diethyl (4-(4-oxo-4H-chromen-2-yl)phenylamino)(4-hydroxy-3-nitrophenyl)methylphosphonate (7e) and diethyl (4-(4-oxo-4H-chromen-2-yl)phenylamino)(benzo[d][1,3]dioxol-6-yl)methylphosphonate (7h) exhibited the highest inhibitory activity against α-amylase in comparison to the reference substance acarbose. The compounds diethyl (4-(4-oxo-4H-chromen-2-yl)phenylamino)(4-fluorophenyl)methylphosphonate (7d), diethyl (4-(4-oxo-4H-chromen-2-yl)phenylamino)(3-(trifluoromethyl)phenyl)methylphosphonate (7 g) and diethyl (4-(4-oxo-4H-chromen-2-yl)phenylamino)(benzo[d][1,3]dioxol-6-yl)methylphosphonate (7h) have shown the highest inhibitory activity against α-glucosidase than the reference drug, Acarbose. The remaining compounds have shown equipotent to good inhibitory activity against both the tested enzymes.

First-line nurse managers play an integral role in ensuring team and organizational effectiveness and quality of care. They are facing increasing challenges arising from the need to lead a generation-diverse workforce. Further research that examines multi-generational perspectives on the competencies of first-line nurse managers is warranted. This paper aimed to elucidate multi-generational perspectives on the competencies required of first-line nurse managers based on their lived experiences and perceptions, as well as those of frontline nurses. A descriptive phenomenological approach was adopted. A total of 48 informants were invited to individual semi-structured interviews to share their perspectives on the competencies required of first-line nurse managers. Findings were analyzed using Van Kaam’s controlled explication method. Four themes that described four areas of competency were generated: (1) advocating for the interests of the staff, (2) allocating resources effectively, (3) building cohesive teams, and (4) embracing change and quality. The findings indicated that there were significant discrepancies among the different generations of informants in terms of their degree of commitment to work, preferred modes of team communication and collaboration, and perspectives on the role and function and preferred leadership styles of first-line nurse managers. This study fell short in examining the experiences of Generation Z nurses, and the findings are subject to further validation by larger samples. However, this study has implications for hospital administrators, nurse educators, and managers, encouraging them to rethink the notion of management competencies to develop effective strategies for leading a multi-generational workforce.

Breakfast is widely acknowledged to be the most important meal of the day. Children who habitually consume Breakfast are more likely to have favourable nutrient intakes including higher intake of dietary fibre, total carbohydrate and lower total fat and cholesterol. Main aim of the study was to evaluate the Effectiveness of Power Point Assisted Teaching regarding Breakfast Skipping among School Children. A Quasi Experimental one group pre-test post-test research design was considered appropriate for the study. 100 School Children were selected through random sampling technique. The data was collected by using Structured Knowledge Questionnaire. The major findings of the study revealed that pre-test mean Knowledge score (6.86), post-test mean Knowledge score (20.86) and the calculated ‘t’ value (60.37) was found to be significant at 0.05 levels. Hence it indicates that the Power Point Assisted Teaching was highly effective in improving Knowledge regarding Breakfast Skipping among School Children. The Chi-square test showed that there was significant association found with variables of Age, Educational status of Students, Occupational status of Father and Mother and Family income per month, rest of the variables were not significantly associated at 0.05 levels of significance. Hence research hypothesis (H2) was accepted. Education Programme using motivating interventions like Power Point Assisted Teaching for School Children was essential to sensitize them about the problems faced by Breakfast Skipping among School Children and the intervention that can be taken to render help to such Children.

Millions of students across the United States cannot benefit fully from a traditional educational program because they have a disability that impairs their ability to participate in a typical classroom environment. For these students, computer-based technologies can play an especially important role. Not only can computer technology facilitate a broader range of educational activities to meet a variety of needs for students with mild learning disorders, but adaptive technology now exists than can enable even those students with severe disabilities to become active learners in the classroom m alongside their peers who do not have disabilities. This article provides an overview of the role computer technology can play in promoting the education of children with special needs within the regular classroom. For example, use of computer technology for word processing, communication, research, and multimedia projects can help the three million students with specific learning and emotional disorders keep up with their nondisabled peers. Computer technology has also enhanced the development of sophisticated devices that can assist the two million students with more severe disabilities in overcoming a wide range of limitations that hinder classroom participation--from speech and hearing impairments to blindness and severe physical disabilities. However, many teachers are not adequately trained on how to use technology effectively in their classrooms, and the cost of the technology is a serious consideration for all schools. Thus, although computer technology has the potential to act as an equalizer by freeing many students from their disabilities, the barriers of inadequate training and cost must first be overcome before more wide- spread use can become a reality.

M-Commerce is one of the classifications of E-Commerce, where the general public or individuals, individuals and business entities can conduct transactions through over the internet that is payments and transferring the money etc. there are different types of mobile commerce applications. Mobile Commerce offers the services like mobile shopping, mobile banking, and mobile payment. In this we also discuss about the how mobile commerce works in day to day life. In this study I took the data from different sources like different websites, online news, advertisements, news papers, e-books and different manual books i.e., Journals etc. the main objective is to provide the various applications services available on the portable devices that is mobiles, laptops, tables etc. to overcome the drawbacks of the desktop computers. M-Commerce is mainly aimed at provide the required information and needs available at any time to the people in a convenient and easy way. But in this mobile commerce there is also drawbacks, it is not secured some times, lake of knowledge in rural area people, poor network connectivity, etc. it is suggested to increasing the mobile commerce services to develop the websites and mobile apps to reach the people throughout the world. And also creating the gateway to enter into the store and provide the store information and store guide.

Genital lesions in a female child cause a lot of apprehension in the parents. Hence, thorough knowledge and proper approach to the diagnosis is very important. The aim of this article is to present an overview of the pattern of diseases affecting genitalia in a female child, significance of these diseases, and an approach to the diagnosis of these diseases. Most of these vulval dermatoses present with one of the four clinical scenarios such as pruritus with/without lesions, pain with/without lesions, discharge with/without lesions, and asymptomatic lesions. The approach to the diagnosis has been discussed accordingly. Diseases such as genital warts and genital herpes which are not common in this age group always raise the suspicion of child sexual abuse. There are certain adult vulval dermatoses such as chronic vulvovaginal candidiasis, which are not seen in prepubertal group.